Epigenetic enzymes: A role in aging and prospects for pharmacological targeting

Epigenetic enzymes: A role in aging and prospects for pharmacological targeting

The growth of interventions aimed toward bettering healthspan is among the precedence duties for the educational and public well being authorities. It can be the principle goal of a novel department in biogerontological analysis, geroscience. According to the geroscience idea, targeting aging is an efficient solution to fight age-related problems. Since aging is an exceptionally advanced course of, system-oriented built-in approaches appear most acceptable for such an interventional technique.

Given the excessive plasticity and adaptability of the epigenome, epigenome-targeted interventions seem extremely promising in geroscience analysis. Pharmaceuticals focused at mechanisms concerned in epigenetic management of gene exercise are actively developed and applied to stop and deal with varied aging-related circumstances resembling cardiometabolic, neurodegenerative, inflammatory problems, and most cancers.

In this overview, we describe the roles of epigenetic mechanisms in aging; characterize enzymes contributing to the regulation of epigenetic processes; significantly concentrate on epigenetic medication, resembling inhibitors of DNA methyltransferases and histone deacetylases which will doubtlessly have an effect on aging-associated illnesses and longevity; and focus on potential caveats related to the usage of epigenetic medication.

Four waves of knowledge from the Chinese Longitudinal Healthy Longevity Survey (CLHLS) have been collected and included 2440 Chinese aged people. The cognitive perform of aged people was measured utilizing the Mini Mental State Examination (MMSE). A nonnormal Growth Mixture mannequin (GMM) with 5 time-invariant covariates was used to determine the totally different trajectories of cognitive decline in aged people.

TA-65 doesn’t enhance telomere size throughout post-natal growth in home sparrow chicks (Passer domesticus)

 

Telomeres, protecting caps on the finish of chromosomes, are sometimes positively associated to lifespan and are regarded as an necessary mechanism of organismal aging. To higher perceive the informal relationships between telomere size and longevity, it’s important to have the ability to experimentally manipulate telomere dynamics (size and loss price).

Previous research recommend that publicity to TA-65, an extract from the Chinese root Astragalus membranaceus, prompts telomerase, lengthens telomeres, will increase the expansion of keratin-based buildings, and boosts the immune system in adults. However, telomere loss is anticipated to be biggest throughout adolescence however whether or not TA-65 has related results throughout this life stage is at the moment unknown.

Here, we experimentally uncovered free-living home sparrow (Passer domesticus) chicks to TA-65 throughout post-natal growth and examined the results on telomere size and loss, progress of keratin-based buildings, and a measure of mobile immunity. Contrary to expectation, the expansion of keratin-based buildings was decreased in TA-65 chicks and in the second yr of the examine, chicks uncovered to TA-65 skilled extra telomere loss than controls.

Epigenetic enzymes: A role in aging and prospects for pharmacological targeting

Beneficial and Detrimental Effects of Reactive Oxygen Species on Lifespan: A Comprehensive Review of Comparative and Experimental Studies

Aging is the best danger issue for a mess of illnesses together with heart problems, neurodegeneration and most cancers. Despite many years of analysis devoted to understanding aging, the mechanisms underlying the aging course of stay incompletely understood. The widely-accepted free radical idea of aging (FRTA) proposes that the buildup of oxidative injury attributable to reactive oxygen species (ROS) is among the major causes of aging.

To outline the connection between ROS and aging, there have been two major approaches: comparative research that measure outcomes associated to ROS throughout species with totally different lifespans, and experimental research that modulate ROS ranges inside a single species utilizing both a genetic or pharmacologic strategy. Comparative research have proven that ranges of ROS and oxidative injury are inversely correlated with lifespan. While these research in basic help the FRTA, any such experiment can solely exhibit correlation, not causation.

Experimental research involving the manipulation of ROS ranges in mannequin organisms have typically proven that interventions that enhance ROS are inclined to lower lifespan, whereas interventions that lower ROS have a tendency to extend lifespan. However, there are additionally a number of examples in which the other is noticed: rising ROS ranges outcomes in prolonged longevity, and lowering ROS ranges outcomes in shortened lifespan. While these research contradict the predictions of the FRTA, these experiments have been carried out in a really restricted variety of species, all of which have a comparatively quick lifespan.

Overall, the info recommend that the connection between ROS and lifespan is advanced, and that ROS can have each useful or detrimental results on longevity relying on the species and circumstances. Accordingly, the connection between ROS and aging is tough to generalize throughout the tree of life. Vitamin D deficiency is frequent amongst older adults, however its affiliation with bodily perform just isn’t totally understood. The purpose of this examine was to analyze the associations between serum 25-hydroxyvitamin D and incapacity in actions of day by day dwelling (ADL), mobility, and goal bodily functioning amongst Chinese older adults.

AAV-1 Helper Free Packaging System
VPK-401 1 kit
EUR 972
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-2 Helper Free Packaging System
VPK-402 1 kit
EUR 972
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-3 Helper Free Packaging System
VPK-403 1 kit
EUR 972
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-4 Helper Free Packaging System
VPK-404 1 kit
EUR 972
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-6 Helper Free Packaging System
VPK-406 1 kit
EUR 972
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-DJ/8 Helper Free Packaging System
VPK-400-DJ-8 1 kit
EUR 972
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-5 Helper Free Expression System
VPK-410-SER5 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-5 Helper Free Promoterless Expression System
VPK-411-SER5 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-5 Helper Free Bicistronic Expression System (Puro)
VPK-415-SER5 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-5 Helper Free Bicistronic Expression System (Neo)
VPK-416-SER5 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-5 Helper Free Bicistronic Expression System (Hygro)
VPK-417-SER5 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-5 Helper Free Bicistronic Expression System (GFP)
VPK-418-SER5 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-5 Helper Free Bicistronic Expression System (Blasticidin)
VPK-419-SER5 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-DJ Helper Free Expression System
VPK-410-DJ 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2.
AAV-1 Helper Free Expression System
VPK-410-SER1 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-2 Helper Free Expression System
VPK-410-SER2 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-3 Helper Free Expression System
VPK-410-SER3 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-4 Helper Free Expression System
VPK-410-SER4 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-6 Helper Free Expression System
VPK-410-SER6 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-DJ/8 Helper Free Expression System
VPK-410-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.
AAV-DJ Helper Free Promoterless Expression System
VPK-411-DJ 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2.
AAV-1 Helper Free Promoterless Expression System
VPK-411-SER1 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-2 Helper Free Promoterless Expression System
VPK-411-SER2 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-3 Helper Free Promoterless Expression System
VPK-411-SER3 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-4 Helper Free Promoterless Expression System
VPK-411-SER4 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-6 Helper Free Promoterless Expression System
VPK-411-SER6 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-DJ/8 Helper Free Promoterless Expression System
VPK-411-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.
AAV-DJ Helper Free Bicistronic Expression System (Puro)
VPK-415-DJ 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2.
AAV-1 Helper Free Bicistronic Expression System (Puro)
VPK-415-SER1 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-2 Helper Free Bicistronic Expression System (Puro)
VPK-415-SER2 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-3 Helper Free Bicistronic Expression System (Puro)
VPK-415-SER3 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-4 Helper Free Bicistronic Expression System (Puro)
VPK-415-SER4 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-6 Helper Free Bicistronic Expression System (Puro)
VPK-415-SER6 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-DJ Helper Free Bicistronic Expression System (Neo)
VPK-416-DJ 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2.
AAV-1 Helper Free Bicistronic Expression System (Neo)
VPK-416-SER1 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-2 Helper Free Bicistronic Expression System (Neo)
VPK-416-SER2 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-3 Helper Free Bicistronic Expression System (Neo)
VPK-416-SER3 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-4 Helper Free Bicistronic Expression System (Neo)
VPK-416-SER4 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-6 Helper Free Bicistronic Expression System (Neo)
VPK-416-SER6 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-DJ Helper Free Bicistronic Expression System (Hygro)
VPK-417-DJ 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2.
AAV-1 Helper Free Bicistronic Expression System (Hygro)
VPK-417-SER1 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-2 Helper Free Bicistronic Expression System (Hygro)
VPK-417-SER2 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-3 Helper Free Bicistronic Expression System (Hygro)
VPK-417-SER3 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-4 Helper Free Bicistronic Expression System (Hygro)
VPK-417-SER4 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-6 Helper Free Bicistronic Expression System (Hygro)
VPK-417-SER6 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-DJ Helper Free Bicistronic Expression System (GFP)
VPK-418-DJ 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2.
AAV-1 Helper Free Bicistronic Expression System (GFP)
VPK-418-SER1 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-2 Helper Free Bicistronic Expression System (GFP)
VPK-418-SER2 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-3 Helper Free Bicistronic Expression System (GFP)
VPK-418-SER3 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-4 Helper Free Bicistronic Expression System (GFP)
VPK-418-SER4 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-6 Helper Free Bicistronic Expression System (GFP)
VPK-418-SER6 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-DJ Helper Free Bicistronic Expression System (Blasticidin)
VPK-419-DJ 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2.
AAV-1 Helper Free Bicistronic Expression System (Blasticidin)
VPK-419-SER1 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-2 Helper Free Bicistronic Expression System (Blasticidin)
VPK-419-SER2 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-3 Helper Free Bicistronic Expression System (Blasticidin)
VPK-419-SER3 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-4 Helper Free Bicistronic Expression System (Blasticidin)
VPK-419-SER4 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-6 Helper Free Bicistronic Expression System (Blasticidin)
VPK-419-SER6 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
scAAV-5 Helper Free Expression System
VPK-430-SER5 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
AAV-DJ/8 Helper Free Bicistronic Expression System (Puro)
VPK-415-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.
AAV-DJ/8 Helper Free Bicistronic Expression System (Neo)
VPK-416-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.
AAV-DJ/8 Helper Free Bicistronic Expression System (Hygro)
VPK-417-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.
AAV-DJ/8 Helper Free Bicistronic Expression System (GFP)
VPK-418-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.
AAV-DJ/8 Helper Free Bicistronic Expression System (Blasticidin)
VPK-419-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.
scAAV-DJ Helper Free Expression System
VPK-430-DJ 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2.
scAAV-1 Helper Free Expression System
VPK-430-SER1 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
scAAV-2 Helper Free Expression System
VPK-430-SER2 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
scAAV-3 Helper Free Expression System
VPK-430-SER3 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
scAAV-4 Helper Free Expression System
VPK-430-SER4 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
scAAV-6 Helper Free Expression System
VPK-430-SER6 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).
scAAV-DJ/8 Helper Free Expression System
VPK-430-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.
ViraSafe Lentiviral Packaging System, Ecotropic
VPK-205 1 kit
EUR 891
Description: Our ViraSafe Lentiviral Packaging Systems contain three packaging plasmids for co-transfection with your own third generation lentiviral expression construct. If you need an expression vector as well as the packaging plasmids, consider our ViraSafe Lentiviral Expression Complete Systems. Our Ecotropic Packaging System assembles lentiviruses with an ecotropic envelope protein which will readily infect only mouse and rat cells via receptor-mediated binding, providing an additional level of safety. However, ecotropic viruses are not as stable upon freezing and will not survive ultracentrifugation procedure
ViraSafe Lentiviral Packaging System, Pantropic
VPK-206 1 kit
EUR 891
Description: Our ViraSafe Lentiviral Packaging Systems contain three packaging plasmids for co-transfection with your own third generation lentiviral expression construct. If you need an expression vector as well as the packaging plasmids, consider our ViraSafe Lentiviral Expression Complete Systems. The Pantropic Packaging System assembles VSVG-pseudotyped lentiviruses which can easily infect virtually any cells regardless of their species of origin.
ViraDuctin AAV Transduction Kit (10 Transductions)
AAV-200 10 transductions
EUR 421
Description: The process by which adeno-associated virus (AAV) infects host cells includes viral binding and entry, intracellular trafficking, nuclear transport, and viral second strand DNA synthesis. The second strand DNA synthesis has been shown to be the rate limiting step, which leads to inefficient transduction by AAV vectors. ViraDuctin AAV Transduction Kit is a proprietary, multi-reagent formulation designed to increase the efficiency of transduction by AAV vectors. Reagent preparation takes only 10 minutes prior to host cell infection.
ViraDuctin AAV Transduction Kit (50 Transductions)
AAV-201 50 transductions
EUR 972
Description: The process by which adeno-associated virus (AAV) infects host cells includes viral binding and entry, intracellular trafficking, nuclear transport, and viral second strand DNA synthesis. The second strand DNA synthesis has been shown to be the rate limiting step, which leads to inefficient transduction by AAV vectors. ViraDuctin AAV Transduction Kit is a proprietary, multi-reagent formulation designed to increase the efficiency of transduction by AAV vectors. Reagent preparation takes only 10 minutes prior to host cell infection.
Human Free PSA (f-PSA) ELISA Kit
PRB-5049-FREE-5 5 x 96 assays
EUR 2283
Human Free PSA (f-PSA) ELISA Kit
PRB-5049-FREE 96 assays
EUR 572
pPACKF1 FIV Lentivector Packaging Kit (50 reactions)
LV100A-5 50 transfections
EUR 2341
  • Category: Lentiviral Technology
ViraBind AAV Purification Mega Kit
VPK-141-5 10 preps
EUR 2312
Description: Purification of adeno-associated virus (AAV) using ultracentrifugation is tedious and time-consuming, and yields can be low. Our ViraBind AAV Purification Kits use a single-step proprietary purification matrix, followed by further purification and concentration with a centrifugal concentrator. The result is a higher viral yield with exceptional purity in a fraction of the time.
Lentivirus Packaging Kit
P904 NULL
EUR 0
Retrovirus Packaging Kit
P905 NULL
EUR 0
Carubicin (Free base)
B1853-5
EUR 457
FIPI (free base)
B2372-5
EUR 196
A23187, free acid
B6646-5 5 mg
EUR 141
Description: A23187, free acid is a Ca2+ ionophore [1]. Ca2+ ionophore acts as a Ca2+ ionophore, allowing Ca2+ to cross cell membranes. A23187, free acid is a Ca2+ ionophore.
Ionomycin free acid
B6947-5 5 mg
EUR 254
Description: Ionomycin is a selective and potent calcium ionophore, which acts as a motile Ca2+ carrier.by direct stimulation of store-regulated cation entry across biological membranes, ionomycin can effectively enhance Ca2+ influx.
MCC950 (Free base)
B1031-5
EUR 457
Apatinib (Free base)
B1613-5
EUR 142
THZ1 (Free base)
9664-5
EUR 294
Adrenorphin, Free Acid
A1017-5 5 mg
EUR 102
Description: Adrenorphin, also sometimes referred to as metorphamide, is an endogenous, C-terminally amidated, opioid octapeptide that is produced from proteolytic cleavage of proenkephalin A and is widely distributed throughout the mammalian brain(1).
LY2835219 free base
A3575-5 5 mg
EUR 142
Description: LY2835219 is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity.
R406 (free base)
A5880-5 5 mg
EUR 166
Description: R406 is a potent SYK inhibitorSpleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase mainly expressed in hematopoietic cells. It transmits signals from a variety of cell surface receptors including CD74, Fc receptor and integrins.
Rucaparib (free base)
A8893-5 5 mg
EUR 137
Description: Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway.
Adrenorphin, Free Acid
5-00628 4 x 5mg Ask for price
TRH, Free Acid
5-02022 4 x 5mg Ask for price
TRH (free acid)
5-02023 4 x 5mg Ask for price
Ionomycin (free acid)
1565-5
EUR 463
Ruxolitinib, Free base
2139-5
EUR 207
Linsitinib, Free base
2294-5
EUR 185
Tipifarnib, Free base
2296-5
EUR 414
Vatalanib, Free Base
2026-5
EUR 126
Pemafibrate, Free Acid
B2670-5 5mg
EUR 166
PLX5622 (free base)
B2965-5 5 mg
EUR 227
TET 830 modified/T – helper epitope from tetanus toxoid
5-02004 4 x 1mg Ask for price
BMS-345541 (Free base)
B1907-5
EUR 414
UNC-926, free base
B2158-5
EUR 196
MK-591, Free acid
B2520-5
EUR 349
SB-334867 free base
B3423-5 5 mg
EUR 128
Description: SB-334867 free base is a selective antagonist of orexin-1 receptor [1].Orexin-A and orexin-B are two peptides isolated from rat hypothalamus. They are involved in some physiological functions such as the control of feeding, energy metabolism and regulation of the sleep-wake cycle.
BMS-345541(free base)
B4655-5 5 mg
EUR 171
Description: BMS-345541(free base) is a selective inhibitor of IKK-1 and IKK-2 with IC50 value of 4?M and 0.3?M, respectively [1].IKK is also known as nuclear factor kappa-B kinase subunit inhibitor and involves in cytokine-activated intracellular signaling pathways.
SGI-1776 free base
A4192-5 5 mg
EUR 154
Description: SGI-1776 free base, N-((1-methylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-amine, is a potent ATP-competitive inhibitor of the serine/threonine family of Pim kinase, an enzyme regulating cell survival.
AM-095 free base
A3167-5 5 mg
EUR 166
Description: AM095 is a novel, potent and orally bioavailable antagonist of lysophosphatidic acid type 1 receptor (LPA1) with IC50 values of 0.73 and 0.98 ?M for mouse or recombinant human LPA1, respectively [1].
[Arg8]-Vasopressin (free acid)
5-00046 4 x 5mg Ask for price
[Lys8]-Vasotocin (free acid)
5-00239 4 x 5mg Ask for price
alfa-MSH, Free Acid
5-00407 4 x 5mg Ask for price
Allatostatin I (free acid)
5-00638 4 x 5mg Ask for price
Cecropin B, Free Acid
5-00956 4 x 1mg Ask for price
Conantokin G (free acid)
5-00990 4 x 5mg Ask for price
GRF (free acid) (human)
5-01255 4 x 1mg Ask for price
Substance P, Free Acid
5-01971 4 x 5mg Ask for price
Urocortin (rat) (free acid)
5-02054 4 x 1mg Ask for price
RGB-286638,  free base
2886-5
EUR 229
EZSolution? Ionomycin free acid
2309-5
EUR 446
StemRegenin 1, Free base
2642-5
EUR 332
GSK-J1 (Free acid)
2761-5
EUR 262
GSK-J4 (Free base)
2762-5
EUR 262
Gastrofensin AN 5 free base
HY-100296 5mg
EUR 2120
LHRH (1-5) (free acid)
H-6212.0005 5.0mg
EUR 151
Description: Sum Formula: C34H38N8O9; CAS# [52434-75-0] net
LHRH (1-5) (free acid)
H-6212.0025 25.0mg
EUR 515
Description: Sum Formula: C34H38N8O9; CAS# [52434-75-0] net
AAV (Intact) Antibody
abx021503-005mg 0.05 mg
EUR 1156
  • Shipped within 5-10 working days.
AAV Replicase antibody
10R-A101a 100 ug
EUR 682
Description: Mouse monoclonal AAV Replicase antibody
AAV antibody (intact)
10R-A110a 50 ug
EUR 589
Description: Mouse monoclonal AAV antibody (intact)
AAV VP1 antibody
10R-A112a 50 ug
EUR 677
Description: Mouse monoclonal AAV VP1 antibody
AAV antibody (intact)
10R-2416 5 mL
EUR 386
Description: Mouse monoclonal AAV intact particle antibody
AAV VP1 antibody
10R-2417 5 mL
EUR 386
Description: Mouse monoclonal AAV VP1 antibody
AAV ELISA Kit
55R-PROPRATV 96 tests
EUR 1111
Description: ELISA kit for detection of AAV in the research laboratory
Bone Dissociation System 5 (Osteoblasts), Rat
4-20215 ea Ask for price
rAAV2-retro helper
PVT15945 2 ug
EUR 325
Luteinizing Hormone-Releasing Hormone, free acid, human; LH-RH, free acid, human
5-01479 4 x 5mg Ask for price
Cholecystokinin Octapeptide free acid (desulfated)
5-00974 4 x 5mg Ask for price
Neuropeptide Y (free acid) (human)
5-01615 4 x 1mg Ask for price
BAY 58-2667 (Free base)
2452-5
EUR 1132
Gryphon Packaging Cell Selection Medium
ABP-TC-PHSM050 50 ml Ask for price
    • Product line: Gryphon Retrovirus
    • Brand: Packaging System
Description: PRODUCT LINE DISCONTINUED. Please contact us.

We used cross-sectional information of 2225 older adults (≥65 years) who participated in the 2011/2012 major survey of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) and the 2012 biomarker sub-study. Serum ranges of 25-hydroxyvitamin D have been measured by enzyme immunoassay. Outcomes included ADL incapacity, mobility incapacity, and incapacity in three goal bodily examinations (standing-up from a chair, picking-up a e-book from the ground, and turning-around 360°).