Human longevity is a fancy phenotype with a major familial part, but little is recognized about its genetic antecedents. Increasing proof from animal fashions means that the insulin/IGF-1 signaling (IIS) pathway is an necessary, evolutionarily conserved organic pathway that influences growing old and longevity. However, so far human knowledge have been scarce. Studies have been hampered by small pattern sizes, lack of exact phenotyping, and inhabitants stratification, amongst different challenges.
Therefore, to extra exactly assess potential genetic contributions to human longevity from genes linked to IIS signaling, we selected a big, homogeneous, long-lived inhabitants of males well-characterized for growing old phenotypes, and we carried out a nested-case management research of 5 candidate longevity genes. Genetic variation inside the FOXO3A gene was strongly associated with human longevity. The OR for homozygous minor vs. homozygous main alleles between the instances and controls was 2.75 (P = 0.00009; adjusted P = 0.00135).
Long-lived males additionally introduced a number of extra phenotypes linked to wholesome growing old, together with decrease prevalence of most cancers and heart problems, higher self-reported well being, and excessive bodily and cognitive perform, regardless of considerably older ages than controls. Several of those growing old phenotypes had been associated with FOXO3A genotype. Long-lived males additionally exhibited a number of organic markers indicative of larger insulin sensitivity and this was associated with homozygosity for the FOXO3A GG genotype. Further exploration of the FOXO3A gene, human longevity and different growing old phenotypes is warranted in different populations.
Oxidative stress influences cell survival and homeostasis, however the mechanisms underlying the organic results of oxidative stress stay to be elucidated. Here, we reveal that the protein kinase MST1 mediates oxidative-stress-induced cell dying in main mammalian neurons by straight activating the FOXO transcription elements. MST1 phosphorylates FOXO proteins at a conserved website inside the forkhead area that disrupts their interplay with 14-3-Three proteins, promotes FOXO nuclear translocation, and thereby induces cell dying in neurons.
We additionally prolong the MST-FOXO signaling hyperlink to nematodes. Knockdown of the C. elegans MST1 ortholog CST-1 shortens life span and accelerates tissue growing old, whereas overexpression of cst-1 promotes life span and delays growing old. The cst-1-induced life-span extension happens in a daf-16-dependent method. The identification of the FOXO transcription elements as main and evolutionarily conserved targets of MST1 means that MST kinases play necessary roles in various organic processes together with mobile responses to oxidative stress and longevity.
Astrocytes as Perspective Targets of Exercise- and Caloric Restriction-Mimetics
Enhanced psychological and bodily exercise can have constructive results on the perform of growing old mind, each within the experimental animals and human sufferers, though mobile mechanisms underlying these results are presently unclear. There is a rising proof that pre-clinical stage of many neurodegenerative illnesses includes modifications in interactions between astrocytes and neurons. Conversely, astrocytes are strategically positioned to mediate the constructive affect of bodily exercise and food regimen on neuronal perform.
Thus, improvement of therapeutic brokers which might enhance the astroglia-neuron communications in ageing mind is of essential significance. Recent advances in research of mobile mechanisms of mind longevity counsel that astrocyte-neuron communications have a significant function within the useful results of caloric restriction, bodily train and their pharmacological mimetics on synaptic homeostasis and cognitive perform.
In explicit, our current knowledge point out that noradrenaline uptake inhibitor atomoxetine can improve astrocytic Ca2+-signaling and astroglia-driven modulation of synaptic plasticity. Similar results had been exhibited by caloric restriction-mimetics metformin and resveratrol. The emerged knowledge additionally counsel that astrocytes may very well be concerned within the modulatory motion of caloric restriction and its mimetics on neuronal autophagy. Still, the effectivity of astrocyte-targeting compounds in stopping age-related cognitive decline is but to be absolutely explored, specifically within the animal fashions of neurodegenerative illnesses and autophagy impairment.
Accelerated Aging and Age-Related Diseases (CVD and Neurological) Due to Air Pollution and Traffic Noise Exposure
The World Health Organization estimates that solely roughly 25% of range in longevity is defined by genetic elements, whereas the opposite 75% is largely decided by interactions with the bodily and social environments. Indeed, growing old is a multifactorial course of that is influenced by a spread of environmental, sociodemographic, and biopsychosocial elements, all of which could act in live performance to find out the method of growing old.
The international common life expectancy elevated basically over the previous century, towards an growing old inhabitants, correlating with the event and onset of age-related illnesses, primarily from cardiovascular and neurological nature. Therefore, the identification of determinants of wholesome and unhealthy growing old is a significant aim to decrease the burden and socioeconomic prices of age-related illnesses.
 ELISA kit) Mouse LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E03A0057-48 |
B-Gene |
1 plate of 48 wells |
EUR 520 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
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Description: A competitive ELISA for quantitative measurement of Mouse LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E03A0057-96 |
B-Gene |
1 plate of 96 wells |
EUR 685 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
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Description: A competitive ELISA for quantitative measurement of Mouse LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 ELISA kit) Rabbit LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E04A0057-192T |
B-Gene |
192 tests |
EUR 1270 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
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Description: A competitive ELISA for quantitative measurement of Rabbit LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E04A0057-48 |
B-Gene |
1 plate of 48 wells |
EUR 520 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
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Description: A competitive ELISA for quantitative measurement of Rabbit LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E04A0057-96 |
B-Gene |
1 plate of 96 wells |
EUR 685 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
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Description: A competitive ELISA for quantitative measurement of Rabbit LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 ELISA kit) Rat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E02A0057-192T |
B-Gene |
192 tests |
EUR 1270 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
|
Description: A competitive ELISA for quantitative measurement of Rat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E02A0057-48 |
B-Gene |
1 plate of 48 wells |
EUR 520 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
|
Description: A competitive ELISA for quantitative measurement of Rat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E02A0057-96 |
B-Gene |
1 plate of 96 wells |
EUR 685 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
|
Description: A competitive ELISA for quantitative measurement of Rat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 ELISA kit) Goat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E06A0057-192T |
B-Gene |
192 tests |
EUR 1270 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
|
Description: A competitive ELISA for quantitative measurement of Goat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E06A0057-48 |
B-Gene |
1 plate of 48 wells |
EUR 520 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
|
Description: A competitive ELISA for quantitative measurement of Goat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E06A0057-96 |
B-Gene |
1 plate of 96 wells |
EUR 685 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
|
Description: A competitive ELISA for quantitative measurement of Goat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 ELISA kit) Human LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E01A0057-192T |
B-Gene |
192 tests |
EUR 1270 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
|
Description: A competitive ELISA for quantitative measurement of Human LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E01A0057-96 |
B-Gene |
1 plate of 96 wells |
EUR 685 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
|
Description: A competitive ELISA for quantitative measurement of Human LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 ELISA kit) Monkey LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E09A0057-192T |
B-Gene |
192 tests |
EUR 1270 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
|
Description: A competitive ELISA for quantitative measurement of Monkey LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E09A0057-48 |
B-Gene |
1 plate of 48 wells |
EUR 520 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
|
Description: A competitive ELISA for quantitative measurement of Monkey LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E09A0057-96 |
B-Gene |
1 plate of 96 wells |
EUR 685 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
|
Description: A competitive ELISA for quantitative measurement of Monkey LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 ELISA kit) Pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E07A0057-192T |
B-Gene |
192 tests |
EUR 1270 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
|
Description: A competitive ELISA for quantitative measurement of Porcine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E07A0057-48 |
B-Gene |
1 plate of 48 wells |
EUR 520 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
|
Description: A competitive ELISA for quantitative measurement of Porcine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E07A0057-96 |
B-Gene |
1 plate of 96 wells |
EUR 685 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
|
Description: A competitive ELISA for quantitative measurement of Porcine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 ELISA kit) Dog LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E08A0057-192T |
B-Gene |
192 tests |
EUR 1270 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
|
Description: A competitive ELISA for quantitative measurement of Canine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E08A0057-48 |
B-Gene |
1 plate of 48 wells |
EUR 520 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
|
Description: A competitive ELISA for quantitative measurement of Canine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E08A0057-96 |
B-Gene |
1 plate of 96 wells |
EUR 685 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
|
Description: A competitive ELISA for quantitative measurement of Canine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Antibody) LAG1 Longevity Assurance Homolog 4 (LASS4) Antibody |
|
20-abx008040 |
Abbexa |
-
EUR 300.00
-
EUR 439.00
-
EUR 189.00
|
|
- Shipped within 5-10 working days.
|
 Antibody) LAG1 Longevity Assurance Homolog 2 (LASS2) Antibody |
|
abx019124-100ug |
Abbexa |
100 ug |
EUR 342 |
- Shipped within 5-10 working days.
|
LAG1 Longevity Assurance Homolog 4 (LASS4) Antibody |
|
20-abx013801 |
Abbexa |
-
EUR 314.00
-
EUR 98.00
-
EUR 398.00
-
EUR 495.00
|
-
100 ug
-
10 ug
-
200 ug
-
300 µg
|
- Shipped within 5-10 working days.
|
 ELISA kit) Guinea pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E05A0057-192T |
B-Gene |
192 tests |
EUR 1270 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
|
Description: A competitive ELISA for quantitative measurement of Guinea pig LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Guinea pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E05A0057-48 |
B-Gene |
1 plate of 48 wells |
EUR 520 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
|
Description: A competitive ELISA for quantitative measurement of Guinea pig LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Guinea pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit |
|
E05A0057-96 |
B-Gene |
1 plate of 96 wells |
EUR 685 |
- Kit contents: 1. MICROTITER PLATE * 1
2. ENZYME CONJUGATE*1 vial
3. STANDARD A*1 vial
4. STANDARD B*1 vial
5. STANDARD C*1 vial
6. STANDARD D*1 vial
7. STANDARD E*1 vial
8. STANDARD F*1 vial
9. SUBSTRATE A*1 vial
10. SUBSTRATE B*1 vial
11. STOP SOLUT
- Show more
|
|
Description: A competitive ELISA for quantitative measurement of Guinea pig LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
) ELISA kit for Human LAG1 longevity assurance homolog 6 (LASS6) |
|
KTE61852-48T |
Abbkine |
48T |
EUR 332 |
- Longevity assurance genes (LAGs) represent a subgroup of the homeobox gene family.Like other LAG family members, the LASS6 protein contained a homeodomain and LAG1 domain. In phylogenetic analyses, it displayed highest homology to LASS5. The correspo
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Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 6 (LASS6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human LAG1 longevity assurance homolog 6 (LASS6) |
|
KTE61852-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2115 |
- Longevity assurance genes (LAGs) represent a subgroup of the homeobox gene family.Like other LAG family members, the LASS6 protein contained a homeodomain and LAG1 domain. In phylogenetic analyses, it displayed highest homology to LASS5. The correspo
- Show more
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Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 6 (LASS6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human LAG1 longevity assurance homolog 6 (LASS6) |
|
KTE61852-96T |
Abbkine |
96T |
EUR 539 |
- Longevity assurance genes (LAGs) represent a subgroup of the homeobox gene family.Like other LAG family members, the LASS6 protein contained a homeodomain and LAG1 domain. In phylogenetic analyses, it displayed highest homology to LASS5. The correspo
- Show more
|
|
Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 6 (LASS6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
) ELISA kit for Human LAG1 longevity assurance homolog 2 (LASS2) |
|
KTE61853-48T |
Abbkine |
48T |
EUR 332 |
- LASS2 has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively splic
- Show more
|
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Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 2 (LASS2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human LAG1 longevity assurance homolog 2 (LASS2) |
|
KTE61853-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2115 |
- LASS2 has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively splic
- Show more
|
|
Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 2 (LASS2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human LAG1 longevity assurance homolog 2 (LASS2) |
|
KTE61853-96T |
Abbkine |
96T |
EUR 539 |
- LASS2 has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively splic
- Show more
|
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Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 2 (LASS2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
 Antibody) Longevity Assurance Homolog 2 (LASS2) Antibody |
|
20-abx177383 |
Abbexa |
|
|
|
|
Longevity Assurance Homolog 2 (LASS2) Antibody |
|
20-abx173382 |
Abbexa |
|
|
|
|
 Antibody) Longevity Assurance Homolog 6 (LASS6) Antibody |
|
abx029719-400ul |
Abbexa |
400 ul |
EUR 523 |
- Shipped within 5-10 working days.
|
Longevity Assurance Homolog 6 (LASS6) Antibody |
|
abx029719-80l |
Abbexa |
80 µl |
EUR 286 |
- Shipped within 5-10 working days.
|
Longevity Assurance Homolog 2 (LASS2) Antibody |
|
abx234705-100ug |
Abbexa |
100 ug |
EUR 551 |
- Shipped within 5-12 working days.
|
 ELISA Kit) Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit |
|
DLR-LASS2-Hu-48T |
DL Develop |
48T |
EUR 554 |
- Should the Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
|
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Longevity Assurance Homolog 2 (LASS2) in samples from tissue homogenates, cell lysates or other biological fluids. |
Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit |
|
DLR-LASS2-Hu-96T |
DL Develop |
96T |
EUR 725 |
- Should the Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
|
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Longevity Assurance Homolog 2 (LASS2) in samples from tissue homogenates, cell lysates or other biological fluids. |
Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit |
|
20-abx152171 |
Abbexa |
-
EUR 7378.00
-
EUR 3933.00
-
EUR 911.00
|
-
10 × 96 tests
-
5 × 96 tests
-
96 tests
|
- Shipped within 5-7 working days.
|
 ELISA Kit) Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit |
|
20-abx258682 |
Abbexa |
-
EUR 7378.00
-
EUR 3933.00
-
EUR 911.00
|
-
10 × 96 tests
-
5 × 96 tests
-
96 tests
|
- Shipped within 5-7 working days.
|
 ELISA Kit) Human Longevity Assurance Homolog 2 (CERS2) ELISA Kit |
|
abx388232-96tests |
Abbexa |
96 tests |
EUR 911 |
- Shipped within 5-12 working days.
|
Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit |
|
RDR-LASS2-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 589 |
Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit |
|
RDR-LASS2-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 820 |
Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit |
|
RD-LASS2-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 563 |
Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit |
|
RD-LASS2-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 783 |
Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit |
|
SEP312Hu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 5189.65 |
- The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Longevity Assurance Homolog 2 (LASS2) were tested on 3 different plates, 8 replicates in each plate
- CV(%) = SD/meanX100
- Intra-Assay: CV<10%
- Inter-Assay
- Show more
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids. |
Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit |
|
SEP312Hu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 515.03 |
- The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Longevity Assurance Homolog 2 (LASS2) were tested on 3 different plates, 8 replicates in each plate
- CV(%) = SD/meanX100
- Intra-Assay: CV<10%
- Inter-Assay
- Show more
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids. |
Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit |
|
SEP312Hu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 692.9 |
- The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Longevity Assurance Homolog 2 (LASS2) were tested on 3 different plates, 8 replicates in each plate
- CV(%) = SD/meanX100
- Intra-Assay: CV<10%
- Inter-Assay
- Show more
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids. |
Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit |
|
SEP312Hu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 2818.05 |
- The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Longevity Assurance Homolog 2 (LASS2) were tested on 3 different plates, 8 replicates in each plate
- CV(%) = SD/meanX100
- Intra-Assay: CV<10%
- Inter-Assay
- Show more
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids. |
Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit |
|
4-SEP312Hu |
Cloud-Clone |
-
EUR 5240.00
-
EUR 2769.00
-
EUR 693.00
|
-
10 plates of 96 wells
-
5 plates of 96 wells
-
1 plate of 96 wells
|
- Known also as Longevity Assurance Homolog 2 elisa. Alternative names of the recognized antigen: SP260
- L3
- TMSG1
- CerS2
- Longevity Assurance(LAG1)Homolog 2
- Ceramide Synthase 2
- LAG1 Longevity Assurance Homolog 2
- Tumor Metastasis Suppressor Gene 1 P
- Show more
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Longevity Assurance Homolog 2 (LASS2) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit |
|
SER156Hu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 5189.65 |
- The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Longevity Assurance Homolog 6 (LASS6) were tested on 3 different plates, 8 replicates in each plate
- CV(%) = SD/meanX100
- Intra-Assay: CV<10%
- Inter-Assay
- Show more
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 6 (LASS6) in Tissue homogenates, cell lysates and other biological fluids. |
Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit |
|
SER156Hu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 515.03 |
- The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Longevity Assurance Homolog 6 (LASS6) were tested on 3 different plates, 8 replicates in each plate
- CV(%) = SD/meanX100
- Intra-Assay: CV<10%
- Inter-Assay
- Show more
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 6 (LASS6) in Tissue homogenates, cell lysates and other biological fluids. |
Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit |
|
SER156Hu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 692.9 |
- The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Longevity Assurance Homolog 6 (LASS6) were tested on 3 different plates, 8 replicates in each plate
- CV(%) = SD/meanX100
- Intra-Assay: CV<10%
- Inter-Assay
- Show more
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 6 (LASS6) in Tissue homogenates, cell lysates and other biological fluids. |
Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit |
|
SER156Hu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 2818.05 |
- The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Longevity Assurance Homolog 6 (LASS6) were tested on 3 different plates, 8 replicates in each plate
- CV(%) = SD/meanX100
- Intra-Assay: CV<10%
- Inter-Assay
- Show more
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 6 (LASS6) in Tissue homogenates, cell lysates and other biological fluids. |
Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit |
|
4-SER156Hu |
Cloud-Clone |
-
EUR 5240.00
-
EUR 2769.00
-
EUR 693.00
|
-
10 plates of 96 wells
-
5 plates of 96 wells
-
1 plate of 96 wells
|
- Known also as Longevity Assurance Homolog 6 elisa. Alternative names of the recognized antigen: CerS6
- Ceramide Synthase 6
- LAG1 longevity assurance homolog 6
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Longevity Assurance Homolog 6 (LASS6) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
) ELISA kit for Human LASS2 (Longevity Assurance Homolog 2) |
|
ELK7214 |
ELK Biotech |
1 plate of 96 wells |
EUR 432 |
- The microtiter plate provided in this kit has been pre-coated with an antibody specific to Longevity Assurance Homolog 2 (LASS2). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific
- Show more
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Description: A sandwich ELISA kit for detection of Longevity Assurance Homolog 2 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
) ELISA kit for Human LASS6 (Longevity Assurance Homolog 6) |
|
ELK7613 |
ELK Biotech |
1 plate of 96 wells |
EUR 432 |
- The microtiter plate provided in this kit has been pre-coated with an antibody specific to Longevity Assurance Homolog 6 (LASS6). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific
- Show more
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Description: A sandwich ELISA kit for detection of Longevity Assurance Homolog 6 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
 CLIA Kit) Human Longevity Assurance Homolog 2 (LASS2) CLIA Kit |
|
20-abx496121 |
Abbexa |
-
EUR 8569.00
-
EUR 4560.00
-
EUR 1052.00
|
-
10 × 96 tests
-
5 × 96 tests
-
96 tests
|
|
|
 CLIA Kit) Human Longevity Assurance Homolog 6 (LASS6) CLIA Kit |
|
20-abx496220 |
Abbexa |
-
EUR 8569.00
-
EUR 4560.00
-
EUR 1052.00
|
-
10 × 96 tests
-
5 × 96 tests
-
96 tests
|
|
|
 Protein) Human Longevity Assurance Homolog 2 (LASS2) Protein |
|
20-abx654210 |
Abbexa |
-
EUR 578.00
-
EUR 258.00
-
EUR 1720.00
-
EUR 690.00
-
EUR 425.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
- Shipped within 5-15 working days.
|
 Antibody) Longevity Assurance Gene 1 Protein Homolog 1 (LASS1) Antibody |
|
abx432242-200ul |
Abbexa |
200 ul |
EUR 384 |
- Shipped within 1-3 working days.
|
 Porcine Protein canopy homolog 3, CNPY3 ELISA KIT |
|
ELI-10589p |
Lifescience Market |
96 Tests |
EUR 928 |
 Porcine Lambda- crystallin homolog, CRYL1 ELISA KIT |
|
ELI-10463p |
Lifescience Market |
96 Tests |
EUR 928 |
 Porcine Protein maelstrom homolog, MAEL ELISA KIT |
|
ELI-43029p |
Lifescience Market |
96 Tests |
EUR 928 |
 ELISA Kit) Porcine Slit2(Slit Homolog 2) ELISA Kit |
|
EP0151 |
FN Test |
96T |
EUR 567.6 |
- Detection range: 0.313-20 ng/ml
- Alias: Slit2(Slit Homolog 2)/SLIT2/SLIL3/slit(Drosophila) homolog 2/slit homolog 2(Drosophila)/slit homolog 2 protein/Slit-2SLIL3
|
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Pig;Sensitivity: 0.188 ng/ml |
 Porcine Teashirt homolog 2, TSHZ2 ELISA KIT |
|
ELI-40365p |
Lifescience Market |
96 Tests |
EUR 928 |
 Porcine Protein Muted homolog, MUTED ELISA KIT |
|
ELI-36857p |
Lifescience Market |
96 Tests |
EUR 928 |
 Slit2 ELISA Kit| Porcine Slit Homolog 2 ELISA Kit |
|
EF016691 |
Lifescience Market |
96 Tests |
EUR 689 |
 Custom Antibody titration by ELISA up to 2 rabbits and 1 bleed |
|
ELISA-1 |
Alpha Diagnostics |
1 |
EUR 202 |
 Porcine Enhancer of rudimentary homolog, ERH ELISA KIT |
|
ELI-09715p |
Lifescience Market |
96 Tests |
EUR 928 |
 Porcine Wilms tumor protein homolog, WT1 ELISA KIT |
|
ELI-17852p |
Lifescience Market |
96 Tests |
EUR 928 |
 Porcine Mothors Against Decapentaplegic Homolog 1 ELISA Kit |
|
EPS0012 |
Abclonal |
96Tests |
EUR 521 |
 Porcine Protein slowmo homolog 2, SLMO2 ELISA KIT |
|
ELI-41005p |
Lifescience Market |
96 Tests |
EUR 928 |
 Porcine Protein delta homolog 2, DLK2 ELISA KIT |
|
ELI-47133p |
Lifescience Market |
96 Tests |
EUR 928 |
 Porcine Mothers against decapentaplegic homolog 3, SMAD3 ELISA K |
|
ELI-07004p |
Lifescience Market |
96 Tests |
EUR 928 |
 Porcine ICAM-3 ELISA Kit |
|
EPI0336 |
Abclonal |
96Tests |
EUR 521 |
 Porcine IL-3 ELISA Kit |
|
EPI0390 |
Abclonal |
96Tests |
EUR 521 |
 Porcine LFA-3 ELISA Kit |
|
EPL0233 |
Abclonal |
96Tests |
EUR 521 |
 Porcine MMP-3 ELISA Kit |
|
EPM0023 |
Abclonal |
96Tests |
EUR 521 |
 Porcine MCP-3 ELISA Kit |
|
EPM0257 |
Abclonal |
96Tests |
EUR 521 |
 Porcine NT-3 ELISA Kit |
|
EPN0025 |
Abclonal |
96Tests |
EUR 521 |
 Porcine PI-3 ELISA Kit |
|
EPP0751 |
Abclonal |
96Tests |
EUR 521 |
 Porcine TIMP-3 ELISA Kit |
|
EPT0525 |
Abclonal |
96Tests |
EUR 521 |
 Porcine VEGFR 3 ELISA Kit |
|
EPV0018 |
Abclonal |
96Tests |
EUR 521 |
 Porcine AQP-3 ELISA Kit |
|
EPA0473 |
Abclonal |
96Tests |
EUR 521 |
 Porcine 3-NT ELISA Kit |
|
EPA0677 |
Abclonal |
96Tests |
EUR 521 |
 Porcine Caspase-3 ELISA Kit |
|
EPC0556 |
Abclonal |
96Tests |
EUR 521 |
 Porcine CA15-3 ELISA Kit |
|
EPC0677 |
Abclonal |
96Tests |
EUR 521 |
 Porcine CCSA-3 ELISA Kit |
|
EPC0717 |
Abclonal |
96Tests |
EUR 521 |
 Porcine CED-3 ELISA Kit |
|
EPC0735 |
Abclonal |
96Tests |
EUR 521 |
 Porcine ENOS-3 ELISA Kit |
|
EPE0165 |
Abclonal |
96Tests |
EUR 521 |
 Porcine GSK-3 ELISA Kit |
|
EPG0031 |
Abclonal |
96Tests |
EUR 521 |
 Porcine Pachytene checkpoint protein 2 homolog, TRIP13 ELISA KIT |
|
ELI-21517p |
Lifescience Market |
96 Tests |
EUR 928 |
The function of environmental elements (comparable to air air pollution and noise publicity) as essential determinants of the growing old course of are being more and more acknowledged. Here, we critically assessment current findings in regards to the pathomechanisms underlying the growing old course of and their correlates in cardiovascular and neurological illness, centered on oxidative stress and irritation, in addition to the affect of outstanding environmental pollution, particularly air air pollution and visitors noise publicity.
