Sirtuins in mammals: insights into their bioalogical function.

Sirtuins in mammals: insights into their bioalogical function.

Sirtuins are a conserved household of proteins discovered in all domains of life. The first identified sirtuin, Sir2 (silent data regulator 2) of Saccharomyces cerevisiae, from which the household derives its title, regulates ribosomal DNA recombination, gene silencing, DNA restore, chromosomal stability and longevity. Sir2 homologues additionally modulate lifespan in worms and flies, and should underlie the useful results of caloric restriction, the one routine that slows growing older and extends lifespan of most lessons of organism, together with mammals.

Sirtuins have gained appreciable consideration for their influence on mammalian physiology, since they could present novel targets for treating illnesses related to growing older and maybe lengthen human lifespan. In this assessment we describe our present understanding of the biological operate of the seven mammalian sirtuins, SIRT1-7, and we will even focus on their potential as mediators of caloric restriction and as pharmacological targets to delay and deal with human age-related illnesses.

The Drosophila melanogaster gene insulin-like receptor (InR) is homologous to mammalian insulin receptors in addition to to Caenorhabditis elegans daf-2, a sign transducer regulating worm dauer formation and grownup longevity. We describe a heteroallelic, hypomorphic genotype of mutant InR, which yields dwarf females with as much as an 85% extension of grownup longevity and dwarf males with decreased late age-specific mortality.

Treatment of the long-lived InR dwarfs with a juvenile hormone analog restores life expectancy towards that of wild-type controls. We conclude that juvenile hormone deficiency, which ends up from InR sign pathway mutation, is ample to increase life-span, and that in flies, insulin-like ligands nonautonomously mediate growing older by retardation of progress or activation of particular endocrine tissue.

FOXO transcription components on the interface between longevity and tumor suppression.

 

A variety of human illnesses, together with most cancers, has a hanging age-dependent onset. However, the molecular mechanisms that join growing older and most cancers are simply starting to be unraveled. FOXO transcription components are promising candidates to function molecular hyperlinks between longevity and tumor suppression. These components are main substrates of the protein kinase Akt.

In the presence of insulin and progress components, FOXO proteins are relocalized from the nucleus to the cytoplasm and degraded through the ubiquitin-proteasome pathway. In the absence of progress components, FOXO proteins translocate to the nucleus and upregulate a sequence of goal genes, thereby selling cell cycle arrest, stress resistance, or apoptosis.

Stress stimuli additionally set off the relocalization of FOXO components into the nucleus, thus permitting an adaptive response to emphasize stimuli. Consistent with the notion that stress resistance is very coupled with lifespan extension, activation of FOXO transcription components in worms and flies will increase longevity. Emerging proof additionally means that FOXO components play a tumor suppressor position in a wide range of cancers. Thus, FOXO proteins translate environmental stimuli into modifications in gene expression applications which will coordinate organismal longevity and tumor suppression.

Mutations in genes affecting endocrine signaling, stress responses, metabolism, and telomeres can all enhance the life spans of mannequin organisms. These mutations have revealed evolutionarily conserved pathways for growing older, a few of which seem to increase life span in response to sensory cues, caloric restriction, or stress. Many mutations affecting longevity pathways delay age-related illness, and the molecular evaluation of those pathways is resulting in a mechanistic understanding of how these two processes–growing older and illness susceptibility–are linked.

Sirtuins in mammals: insights into their bioalogical function.

Inflammgrowing older and anti-inflammgrowing older: a systemic perspective on growing older and longevity emerged from research in people.

 

A big a part of the growing older phenotype, together with immunosenescence, is defined by an imbalance between inflammatory and anti-inflammatory networks, which ends up in the low grade persistent pro-inflammatory standing we proposed to name inflammgrowing older. Within this angle, wholesome growing older and longevity are possible the outcome not solely of a decrease propensity to mount inflammatory responses but additionally of environment friendly anti-inflammatory networks, which in regular growing older fail to completely neutralize the inflammatory processes consequent to the lifelong antigenic burden and publicity to damgrowing older brokers.

Such a world imbalance could be a main driving pressure for frailty and widespread age-related pathologies, and needs to be addressed and studied inside an evolutionary-based programs biology perspective. Evidence in favor of this conceptualization largely derives from research in people. We thus suggest that inflammgrowing older could be flanked by anti-inflammgrowing older as main determinants not solely of immunosenescence however ultimately of world growing older and longevity.

The FoxO household of Forkhead transcription components performs an vital position in longevity and tumor suppression by upregulating goal genes concerned in stress resistance, metabolism, cell cycle arrest and apoptosis. FoxO transcription components translate a wide range of environmental stimuli, together with insulin, progress components, vitamins and oxidative stress, into particular gene-expression applications.

These environmental stimuli management FoxO exercise primarily by regulating their subcellular localization, but additionally by affecting their protein ranges, DNA-binding properties and transcriptional exercise. The exact regulation of FoxO transcription components is enacted by an intricate mixture of post-translational modifications (PTMs), together with phosphorylation, acetylation and ubiquitination, and binding protein companions.

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E01A0057-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Human LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E03A0057-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Mouse LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E03A0057-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Mouse LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E03A0057-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E02A0057-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E02A0057-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E02A0057-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E07A0057-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Porcine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E07A0057-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Porcine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E07A0057-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Porcine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E06A0057-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Goat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E06A0057-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Goat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E06A0057-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Goat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E04A0057-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rabbit LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E04A0057-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rabbit LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E04A0057-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rabbit LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E08A0057-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Canine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E08A0057-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Canine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E08A0057-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Canine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E09A0057-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Monkey LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E09A0057-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Monkey LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E09A0057-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Monkey LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

ELISA kit for Human LAG1 longevity assurance homolog 2 (LASS2)

KTE61853-48T 48T
EUR 332
Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 2 (LASS2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human LAG1 longevity assurance homolog 2 (LASS2)

KTE61853-5platesof96wells 5 plates of 96 wells
EUR 2115
Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 2 (LASS2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human LAG1 longevity assurance homolog 2 (LASS2)

KTE61853-96T 96T
EUR 539
Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 2 (LASS2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Guinea pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E05A0057-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Guinea pig LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E05A0057-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Guinea pig LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit

E05A0057-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Guinea pig LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit

SER156Hu-10x96wellstestplate 10x96-wells test plate
EUR 5189.65
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 6 (LASS6) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit

SER156Hu-1x48wellstestplate 1x48-wells test plate
EUR 515.03
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 6 (LASS6) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit

SER156Hu-1x96wellstestplate 1x96-wells test plate
EUR 692.9
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 6 (LASS6) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit

SER156Hu-5x96wellstestplate 5x96-wells test plate
EUR 2818.05
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 6 (LASS6) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit

4-SER156Hu
  • EUR 5240.00
  • EUR 2769.00
  • EUR 693.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Longevity Assurance Homolog 6 (LASS6) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit

20-abx258682
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Longevity Assurance Homolog 6 (LASS6) Antibody

abx029719-400ul 400 ul
EUR 523

Longevity Assurance Homolog 6 (LASS6) Antibody

abx029719-80l 80 µl
EUR 286

Human Longevity Assurance Homolog 6 (LASS6) CLIA Kit

20-abx496220
  • EUR 8569.00
  • EUR 4560.00
  • EUR 1052.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

ELISA kit for Human LASS6 (Longevity Assurance Homolog 6)

ELK7613 1 plate of 96 wells
EUR 432
Description: A sandwich ELISA kit for detection of Longevity Assurance Homolog 6 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit

SEP312Hu-5x96wellstestplate 5x96-wells test plate
EUR 2818.05
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit

4-SEP312Hu
  • EUR 5240.00
  • EUR 2769.00
  • EUR 693.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Longevity Assurance Homolog 2 (LASS2) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit

SEP312Hu-10x96wellstestplate 10x96-wells test plate
EUR 5189.65
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit

SEP312Hu-1x48wellstestplate 1x48-wells test plate
EUR 515.03
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit

SEP312Hu-1x96wellstestplate 1x96-wells test plate
EUR 692.9
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit

RD-LASS2-Hu-48Tests 48 Tests
EUR 563

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit

RD-LASS2-Hu-96Tests 96 Tests
EUR 783

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit

DLR-LASS2-Hu-48T 48T
EUR 554
Description: A sandwich quantitative ELISA assay kit for detection of Human Longevity Assurance Homolog 2 (LASS2) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit

DLR-LASS2-Hu-96T 96T
EUR 725
Description: A sandwich quantitative ELISA assay kit for detection of Human Longevity Assurance Homolog 2 (LASS2) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit

20-abx152171
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Longevity Assurance Homolog 2 (CERS2) ELISA Kit

abx388232-96tests 96 tests
EUR 911

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit

RDR-LASS2-Hu-48Tests 48 Tests
EUR 589

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit

RDR-LASS2-Hu-96Tests 96 Tests
EUR 820

Longevity Assurance Homolog 2 (LASS2) Antibody

abx234705-100ug 100 ug
EUR 551

Longevity Assurance Homolog 2 (LASS2) Antibody

20-abx177383
  • EUR 1316.00
  • EUR 620.00
  • 1 mg
  • 200 ug

Longevity Assurance Homolog 2 (LASS2) Antibody

20-abx173382
  • EUR 926.00
  • EUR 467.00
  • 1 mg
  • 200 ug

Human Longevity Assurance Homolog 2 (LASS2) Protein

20-abx654210
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Longevity Assurance Homolog 2 (LASS2) CLIA Kit

20-abx496121
  • EUR 8569.00
  • EUR 4560.00
  • EUR 1052.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

ELISA kit for Human LASS2 (Longevity Assurance Homolog 2)

ELK7214 1 plate of 96 wells
EUR 432
Description: A sandwich ELISA kit for detection of Longevity Assurance Homolog 2 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Longevity Assurance Gene 1 Protein Homolog 1 (LASS1) Antibody

abx432242-200ul 200 ul
EUR 384

Individual Reaction Mix 6

G065-6 200 reactions
EUR 167

Mouse IL-6 Recombinant Protein

R00102-6 5ug/vial
EUR 259
Description: Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. Mouse IL-6 Recombinant Protein is purified interleukin-6 produced in yeast.

Tissue Culture Plate, 6 Well

TCP20-6 1 UNIT
EUR 53.48

Random Nanofibers 6 Well Plate

3D00006-6 700 nm-PCLs
EUR 93

Aligned Nanofibers 6 Well Plate

3D00012-6 700 nm-PCLs
EUR 97

pLenti-CLDN1 shRNA-6 Plasmid

PVTBAV04867-6 2 ug
EUR 356

Human Frizzled Homolog 6 (FZD6) ELISA Kit

SEE576Hu-10x96wellstestplate 10x96-wells test plate
EUR 4731.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Frizzled Homolog 6 (FZD6) in Tissue homogenates and other biological fluids.

Human Frizzled Homolog 6 (FZD6) ELISA Kit

SEE576Hu-1x48wellstestplate 1x48-wells test plate
EUR 477.3
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Frizzled Homolog 6 (FZD6) in Tissue homogenates and other biological fluids.

Human Frizzled Homolog 6 (FZD6) ELISA Kit

SEE576Hu-1x96wellstestplate 1x96-wells test plate
EUR 639
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Frizzled Homolog 6 (FZD6) in Tissue homogenates and other biological fluids.

Human Frizzled Homolog 6 (FZD6) ELISA Kit

SEE576Hu-5x96wellstestplate 5x96-wells test plate
EUR 2575.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Frizzled Homolog 6 (FZD6) in Tissue homogenates and other biological fluids.

Human Frizzled Homolog 6 (FZD6) ELISA Kit

4-SEE576Hu
  • EUR 4782.00
  • EUR 2526.00
  • EUR 640.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Frizzled Homolog 6 (FZD6) in samples from Tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Human Frizzled Homolog 6 (FZD6) ELISA Kit

RD-FZD6-Hu-48Tests 48 Tests
EUR 521

Human Frizzled Homolog 6 (FZD6) ELISA Kit

RD-FZD6-Hu-96Tests 96 Tests
EUR 723

Human B7H6/ B7 homolog 6 ELISA Kit

E2885Hu 1 Kit
EUR 605

Human Frizzled Homolog 6 (FZD6) ELISA Kit

DLR-FZD6-Hu-48T 48T
EUR 517
Description: A sandwich quantitative ELISA assay kit for detection of Human Frizzled Homolog 6 (FZD6) in samples from tissue homogenates or other biological fluids.

Human Frizzled Homolog 6 (FZD6) ELISA Kit

DLR-FZD6-Hu-96T 96T
EUR 673
Description: A sandwich quantitative ELISA assay kit for detection of Human Frizzled Homolog 6 (FZD6) in samples from tissue homogenates or other biological fluids.

Human Frizzled Homolog 6 (FZD6)ELISA Kit

201-12-2368 96 tests
EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Frizzled Homolog 6 (FZD6) ELISA Kit

20-abx151587
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Chromobox Homolog 6 (CBX6) ELISA Kit

20-abx386319
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Frizzled Homolog 6 (FZD6) ELISA Kit

RDR-FZD6-Hu-48Tests 48 Tests
EUR 544

Human Frizzled Homolog 6 (FZD6) ELISA Kit

RDR-FZD6-Hu-96Tests 96 Tests
EUR 756

Human Frizzled Homolog 6(FZD6)ELISA Kit

QY-E02701 96T
EUR 394

Human B7H6(B7 homolog 6) ELISA Kit

EH2307 96T
EUR 567.6
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human B7 homolog 6, B7H6 ELISA KIT

ELI-07534h 96 Tests
EUR 824

Custom Antibody titration by ELISA up to 2 rabbits and 1 bleed

ELISA-1 1
EUR 202

ExoStd? Lyophilized Exosome Standard (30 µg, Human Plasma, 6 vials)

M1040-6
EUR 1300

ExoStd? Lyophilized Exosome Standard (100 µg, Human Plasma, 6 vials)

M1041-6
EUR 1572

ExoStd? Lyophilized Exosome Standard (30 µg, Human Serum, 6 vials)

M1042-6
EUR 1300

ExoStd? Lyophilized Exosome Standard (100 µg, Human Serum, 6 vials)

M1043-6
EUR 1572

ExoStd? Lyophilized Exosome Standard (30 µg, Human Urine, 6 vials)

M1044-6
EUR 1289

ExoStd? Lyophilized Exosome Standard (100 µg, Human Urine, 6 vials)

M1045-6
EUR 1572

ExoStd? Lyophilized Exosome Standard (30 µg, Human Saliva, 6 vials)

M1046-6
EUR 1306

ExoStd? Lyophilized Exosome Standard (100 µg, Human Saliva, 6 vials)

M1047-6
EUR 1621

Aligned Nanofibers 6 Well Plate Inserts

3D00016-6 700 nm-PCLs
EUR 98

An intriguing chance is that FoxO PTMs could act as a ‘molecular FoxO code’ learn by selective protein companions to quickly regulate gene-expression applications. The efficient management of FoxO exercise in response to environmental stimuli is prone to be important to stop growing older and age-dependent illnesses, together with most cancers, neurodegenerative illnesses and diabetes.