Month: March 2021

Sirtuins in mammals: insights into their bioalogical function.

Sirtuins in mammals: insights into their bioalogical function.

Sirtuins are a conserved household of proteins discovered in all domains of life. The first identified sirtuin, Sir2 (silent data regulator 2) of Saccharomyces cerevisiae, from which the household derives its title, regulates ribosomal DNA recombination, gene silencing, DNA restore, chromosomal stability and longevity. Sir2 homologues additionally modulate lifespan in worms and flies, and should underlie the useful results of caloric restriction, the one routine that slows growing older and extends lifespan of most lessons of organism, together with mammals.

Sirtuins have gained appreciable consideration for their influence on mammalian physiology, since they could present novel targets for treating illnesses related to growing older and maybe lengthen human lifespan. In this assessment we describe our present understanding of the biological operate of the seven mammalian sirtuins, SIRT1-7, and we will even focus on their potential as mediators of caloric restriction and as pharmacological targets to delay and deal with human age-related illnesses.

The Drosophila melanogaster gene insulin-like receptor (InR) is homologous to mammalian insulin receptors in addition to to Caenorhabditis elegans daf-2, a sign transducer regulating worm dauer formation and grownup longevity. We describe a heteroallelic, hypomorphic genotype of mutant InR, which yields dwarf females with as much as an 85% extension of grownup longevity and dwarf males with decreased late age-specific mortality.

Treatment of the long-lived InR dwarfs with a juvenile hormone analog restores life expectancy towards that of wild-type controls. We conclude that juvenile hormone deficiency, which ends up from InR sign pathway mutation, is ample to increase life-span, and that in flies, insulin-like ligands nonautonomously mediate growing older by retardation of progress or activation of particular endocrine tissue.

FOXO transcription components on the interface between longevity and tumor suppression.

 

A variety of human illnesses, together with most cancers, has a hanging age-dependent onset. However, the molecular mechanisms that join growing older and most cancers are simply starting to be unraveled. FOXO transcription components are promising candidates to function molecular hyperlinks between longevity and tumor suppression. These components are main substrates of the protein kinase Akt.

In the presence of insulin and progress components, FOXO proteins are relocalized from the nucleus to the cytoplasm and degraded through the ubiquitin-proteasome pathway. In the absence of progress components, FOXO proteins translocate to the nucleus and upregulate a sequence of goal genes, thereby selling cell cycle arrest, stress resistance, or apoptosis.

Stress stimuli additionally set off the relocalization of FOXO components into the nucleus, thus permitting an adaptive response to emphasize stimuli. Consistent with the notion that stress resistance is very coupled with lifespan extension, activation of FOXO transcription components in worms and flies will increase longevity. Emerging proof additionally means that FOXO components play a tumor suppressor position in a wide range of cancers. Thus, FOXO proteins translate environmental stimuli into modifications in gene expression applications which will coordinate organismal longevity and tumor suppression.

Mutations in genes affecting endocrine signaling, stress responses, metabolism, and telomeres can all enhance the life spans of mannequin organisms. These mutations have revealed evolutionarily conserved pathways for growing older, a few of which seem to increase life span in response to sensory cues, caloric restriction, or stress. Many mutations affecting longevity pathways delay age-related illness, and the molecular evaluation of those pathways is resulting in a mechanistic understanding of how these two processes–growing older and illness susceptibility–are linked.

Sirtuins in mammals: insights into their bioalogical function.

Inflammgrowing older and anti-inflammgrowing older: a systemic perspective on growing older and longevity emerged from research in people.

 

A big a part of the growing older phenotype, together with immunosenescence, is defined by an imbalance between inflammatory and anti-inflammatory networks, which ends up in the low grade persistent pro-inflammatory standing we proposed to name inflammgrowing older. Within this angle, wholesome growing older and longevity are possible the outcome not solely of a decrease propensity to mount inflammatory responses but additionally of environment friendly anti-inflammatory networks, which in regular growing older fail to completely neutralize the inflammatory processes consequent to the lifelong antigenic burden and publicity to damgrowing older brokers.

Such a world imbalance could be a main driving pressure for frailty and widespread age-related pathologies, and needs to be addressed and studied inside an evolutionary-based programs biology perspective. Evidence in favor of this conceptualization largely derives from research in people. We thus suggest that inflammgrowing older could be flanked by anti-inflammgrowing older as main determinants not solely of immunosenescence however ultimately of world growing older and longevity.

The FoxO household of Forkhead transcription components performs an vital position in longevity and tumor suppression by upregulating goal genes concerned in stress resistance, metabolism, cell cycle arrest and apoptosis. FoxO transcription components translate a wide range of environmental stimuli, together with insulin, progress components, vitamins and oxidative stress, into particular gene-expression applications.

These environmental stimuli management FoxO exercise primarily by regulating their subcellular localization, but additionally by affecting their protein ranges, DNA-binding properties and transcriptional exercise. The exact regulation of FoxO transcription components is enacted by an intricate mixture of post-translational modifications (PTMs), together with phosphorylation, acetylation and ubiquitination, and binding protein companions.

Human LAG1 longevity assurance homolog 6 (LASS6) ELISA Kit
AE35956HU-48T 48T
EUR 325
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 6 (LASS6) ELISA Kit
AE35956HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 6 (LASS6) ELISA Kit
AE35956HU-96T 96T
EUR 610
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 6 (LASS6) ELISA Kit
AE35956HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 6 (LASS6) ELISA Kit
EK10150 96Т
EUR 799

Human LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS075268-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS075268-48StripWells 48-Strip-Wells
EUR 550

Human LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS075268-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS075268-96StripWells 96-Strip-Wells
EUR 765

Human LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS077807-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS077807-48StripWells 48-Strip-Wells
EUR 550

Human LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS077807-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS077807-96StripWells 96-Strip-Wells
EUR 765

Human LAG1 Longevity Assurance Homolog 3 ELISA Kit
MBS047385-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human LAG1 Longevity Assurance Homolog 3 ELISA Kit
MBS047385-48StripWells 48-Strip-Wells
EUR 550

Human LAG1 Longevity Assurance Homolog 3 ELISA Kit
MBS047385-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human LAG1 Longevity Assurance Homolog 3 ELISA Kit
MBS047385-96StripWells 96-Strip-Wells
EUR 765

Human LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS101362-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS101362-48StripWells 48-Strip-Wells
EUR 550

Human LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS101362-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS101362-96StripWells 96-Strip-Wells
EUR 765

Human LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS091574-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS091574-48StripWells 48-Strip-Wells
EUR 550

Human LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS091574-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS091574-96StripWells 96-Strip-Wells
EUR 765

Cat LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS068990-INQUIRE INQUIRE Ask for price

Rat LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS053900-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS053900-48StripWells 48-Strip-Wells
EUR 550

Rat LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS053900-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS053900-96StripWells 96-Strip-Wells
EUR 765

Cavy LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS074625-INQUIRE INQUIRE Ask for price

Goat LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS055336-INQUIRE INQUIRE Ask for price

Duck LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS047759-INQUIRE INQUIRE Ask for price

Fish LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS100595-INQUIRE INQUIRE Ask for price

Goose LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS077119-INQUIRE INQUIRE Ask for price

Horse LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS064598-10x96StripWells 10x96-Strip-Wells
EUR 6725

Horse LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS064598-48StripWells 48-Strip-Wells
EUR 550

Horse LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS064598-5x96StripWells 5x96-Strip-Wells
EUR 3420

Horse LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS064598-96StripWells 96-Strip-Wells
EUR 765

Sheep LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS059537-10x96StripWells 10x96-Strip-Wells
EUR 6725

Sheep LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS059537-48StripWells 48-Strip-Wells
EUR 550

Sheep LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS059537-5x96StripWells 5x96-Strip-Wells
EUR 3420

Sheep LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS059537-96StripWells 96-Strip-Wells
EUR 765

Camel LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS058489-10x96StripWells 10x96-Strip-Wells
EUR 6725

Camel LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS058489-48StripWells 48-Strip-Wells
EUR 550

Camel LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS058489-5x96StripWells 5x96-Strip-Wells
EUR 3420

Camel LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS058489-96StripWells 96-Strip-Wells
EUR 765

Mouse LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS054524-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS054524-48StripWells 48-Strip-Wells
EUR 550

Mouse LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS054524-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS054524-96StripWells 96-Strip-Wells
EUR 765

Monkey LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS102469-10x96StripWells 10x96-Strip-Wells
EUR 6725

Monkey LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS102469-48StripWells 48-Strip-Wells
EUR 550

Monkey LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS102469-5x96StripWells 5x96-Strip-Wells
EUR 3420

Monkey LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS102469-96StripWells 96-Strip-Wells
EUR 765

Bovine LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS056547-10x96StripWells 10x96-Strip-Wells
EUR 6725

Bovine LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS056547-48StripWells 48-Strip-Wells
EUR 550

Bovine LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS056547-5x96StripWells 5x96-Strip-Wells
EUR 3420

Bovine LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS056547-96StripWells 96-Strip-Wells
EUR 765

Rabbit LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS053775-INQUIRE INQUIRE Ask for price

Donkey LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS101702-INQUIRE INQUIRE Ask for price

Pigeon LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS093989-INQUIRE INQUIRE Ask for price

Canine LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS095735-10x96StripWells 10x96-Strip-Wells
EUR 6725

Canine LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS095735-48StripWells 48-Strip-Wells
EUR 550

Canine LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS095735-5x96StripWells 5x96-Strip-Wells
EUR 3420

Canine LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS095735-96StripWells 96-Strip-Wells
EUR 765

Chicken LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS106622-INQUIRE INQUIRE Ask for price

Hamster LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS078263-10x96StripWells 10x96-Strip-Wells
EUR 6725

Hamster LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS078263-48StripWells 48-Strip-Wells
EUR 550

Hamster LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS078263-5x96StripWells 5x96-Strip-Wells
EUR 3420

Hamster LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS078263-96StripWells 96-Strip-Wells
EUR 765

Porcine LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS084258-10x96StripWells 10x96-Strip-Wells
EUR 6725

Porcine LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS084258-48StripWells 48-Strip-Wells
EUR 550

Porcine LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS084258-5x96StripWells 5x96-Strip-Wells
EUR 3420

Porcine LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS084258-96StripWells 96-Strip-Wells
EUR 765

ELISA kit for Human LAG1 longevity assurance homolog 6 (LASS6)
KTE61852-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 6 (LASS6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human LAG1 longevity assurance homolog 6 (LASS6)
KTE61852-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 6 (LASS6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human LAG1 longevity assurance homolog 6 (LASS6)
KTE61852-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 6 (LASS6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E01A0057-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E01A0057-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human LAG1 longevity assurance homolog 4 (LASS4) ELISA Kit
AE35958HU-48T 48T
EUR 325
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 4 (LASS4) ELISA Kit
AE35958HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 4 (LASS4) ELISA Kit
AE35958HU-96T 96T
EUR 610
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 4 (LASS4) ELISA Kit
AE35958HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 2 (LASS2) ELISA Kit
AE35962HU-48T 48T
EUR 325
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 2 (LASS2) ELISA Kit
AE35962HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 2 (LASS2) ELISA Kit
AE35962HU-96T 96T
EUR 610
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 2 (LASS2) ELISA Kit
AE35962HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 1 (LASS1) ELISA Kit
AE35965HU-48T 48T
EUR 325
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 1 (LASS1) ELISA Kit
AE35965HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 1 (LASS1) ELISA Kit
AE35965HU-96T 96T
EUR 610
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 1 (LASS1) ELISA Kit
AE35965HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 2 (LASS2) ELISA Kit
EK10151 96Т
EUR 799

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA Kit
EIA06676h each
EUR 430

Human LAG1 longevity assurance homolog 4 (LASS4) ELISA Kit
MBS2803629-10x96StripWells 10x96-Strip-Wells
EUR 6255

Human LAG1 longevity assurance homolog 4 (LASS4) ELISA Kit
MBS2803629-48StripWells 48-Strip-Wells
EUR 445

Human LAG1 longevity assurance homolog 4 (LASS4) ELISA Kit
MBS2803629-5x96StripWells 5x96-Strip-Wells
EUR 3290

Human LAG1 longevity assurance homolog 4 (LASS4) ELISA Kit
MBS2803629-96StripWells 96-Strip-Wells
EUR 730

Human LAG1 longevity assurance homolog 1 (LASS1) ELISA Kit
MBS2803630-10x96StripWells 10x96-Strip-Wells
EUR 6255

Human LAG1 longevity assurance homolog 1 (LASS1) ELISA Kit
MBS2803630-48StripWells 48-Strip-Wells
EUR 445

Human LAG1 longevity assurance homolog 1 (LASS1) ELISA Kit
MBS2803630-5x96StripWells 5x96-Strip-Wells
EUR 3290

Human LAG1 longevity assurance homolog 1 (LASS1) ELISA Kit
MBS2803630-96StripWells 96-Strip-Wells
EUR 730

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA Kit
MBS269956-10x96StripWells 10x96-Strip-Wells
EUR 3040

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA Kit
MBS269956-48StripWells 48-Strip-Wells
EUR 285

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA Kit
MBS269956-5x96StripWells 5x96-Strip-Wells
EUR 1670

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA Kit
MBS269956-96StripWells 96-Strip-Wells
EUR 405

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA Kit
NSL1442Hu 96 wells
EUR 468
Description: Sandwich ELISA

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA Kit
MBS7227056-10x96StripWells 10x96-Strip-Wells
EUR 5685

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA Kit
MBS7227056-48StripWells 48-Strip-Wells
EUR 485

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA Kit
MBS7227056-5x96StripWells 5x96-Strip-Wells
EUR 3020

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA Kit
MBS7227056-96StripWells 96-Strip-Wells
EUR 690

Human LAG1 longevity assurance homolog 1 (LASS1) ELISA Kit
RK10479 96T
EUR 322.37

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A0054 96T
EUR 700
Description: ELISA

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A0057-48wellsplate 48 wells plate
EUR 280

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A0057-96wellsplate 96 wells plate
EUR 405

Cat LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS108523-INQUIRE INQUIRE Ask for price

Cat LAG1 Longevity Assurance Homolog 3 ELISA Kit
MBS073954-INQUIRE INQUIRE Ask for price

Cat LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS071564-INQUIRE INQUIRE Ask for price

Cat LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS055496-INQUIRE INQUIRE Ask for price

Rat LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS061441-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS061441-48StripWells 48-Strip-Wells
EUR 550

Rat LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS061441-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS061441-96StripWells 96-Strip-Wells
EUR 765

Rat LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS060489-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS060489-48StripWells 48-Strip-Wells
EUR 550

Rat LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS060489-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS060489-96StripWells 96-Strip-Wells
EUR 765

Rat LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS052400-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS052400-48StripWells 48-Strip-Wells
EUR 550

Rat LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS052400-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS052400-96StripWells 96-Strip-Wells
EUR 765

Cat LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS050986-INQUIRE INQUIRE Ask for price

Rat LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS057368-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS057368-48StripWells 48-Strip-Wells
EUR 550

Rat LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS057368-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS057368-96StripWells 96-Strip-Wells
EUR 765

Rat LAG1 Longevity Assurance Homolog 3 ELISA Kit
MBS048358-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat LAG1 Longevity Assurance Homolog 3 ELISA Kit
MBS048358-48StripWells 48-Strip-Wells
EUR 550

Rat LAG1 Longevity Assurance Homolog 3 ELISA Kit
MBS048358-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat LAG1 Longevity Assurance Homolog 3 ELISA Kit
MBS048358-96StripWells 96-Strip-Wells
EUR 765

Plant LAG1 Longevity Assurance Homolog 6 (LASS6) ELISA Kit
MBS9379273-INQUIRE INQUIRE Ask for price

Fish LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS085893-INQUIRE INQUIRE Ask for price

Duck LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS104513-INQUIRE INQUIRE Ask for price

Cavy LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS071049-INQUIRE INQUIRE Ask for price

Cavy LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS066331-INQUIRE INQUIRE Ask for price

Goat LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS073315-INQUIRE INQUIRE Ask for price

Cavy LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS076246-INQUIRE INQUIRE Ask for price

Duck LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS059925-INQUIRE INQUIRE Ask for price

Duck LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS058160-INQUIRE INQUIRE Ask for price

An intriguing chance is that FoxO PTMs could act as a ‘molecular FoxO code’ learn by selective protein companions to quickly regulate gene-expression applications. The efficient management of FoxO exercise in response to environmental stimuli is prone to be important to stop growing older and age-dependent illnesses, together with most cancers, neurodegenerative illnesses and diabetes.

Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors.

Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors.

Cells from organisms with renewable tissues can completely withdraw from the cell cycle in response to various stress, together with dysfunctional telomeres, DNA harm, sturdy mitogenic alerts, and disrupted chromatin. This response, termed mobile senescence, is managed by the p53 and RB tumor suppressor proteins and constitutes a potent anticancer mechanism.

Nonetheless, senescent cells purchase phenotypic modifications which will contribute to ageing and sure age-related ailments, together with late-life most cancers. Thus, the senescence response could also be antagonistically pleiotropic, selling early-life survival by curbing the event of most cancers however ultimately limiting longevity as dysfunctional senescent cells accumulate.

Numerous research reveal hyperlinks between persistent stress and indices of poor well being, together with danger components for heart problems and poorer immune operate. Nevertheless, the precise mechanisms of how stress will get “underneath the pores and skin” stay elusive. We investigated the speculation that stress impacts well being by modulating the speed of mobile ageing.

Here we offer proof that psychological stress–both perceived stress and chronicity of stress–is considerably related to larger oxidative stress, decrease telomerase exercise, and shorter telomere size, that are recognized determinants of cell senescence and longevity, in peripheral blood mononuclear cells from wholesome premenopausal girls. Women with the very best ranges of perceived stress have telomeres shorter on common by the equal of no less than one decade of further ageing in comparison with low stress girls. These findings have implications for understanding how, on the mobile degree, stress might promote earlier onset of age-related ailments.

The Caenorhabditis elegans transcription issue HSF-1, which regulates the heat-shock response, additionally influences ageing. Reducing hsf-1 exercise accelerates tissue ageing and shortens life-span, and we present that hsf-1 overexpression extends lifespan. We discover that HSF-1, just like the transcription issue DAF-16, is required for daf-2-insulin/IGF-1 receptor mutations to increase life-span.

Our findings counsel it is because HSF-1 and DAF-16 collectively activate expression of particular genes, together with genes encoding small heat-shock proteins, which in flip promote longevity. The small heat-shock proteins additionally delay the onset of polyglutamine-expansion protein aggregation, suggesting that these proteins couple the conventional ageing course of to such a age-related illness.

The SIR2/3/four advanced and SIR2 alone promote longevity in Saccharomyces cerevisiae by two completely different mechanisms.

 

The SIR genes are determinants of life span in yeast mom cells. Here we present that life span regulation by the Sir proteins is unbiased of their position in nonhomologous finish becoming a member of. The quick life span of a sir3 or sir4 mutant is as a result of simultaneous expression of a and alpha mating-type data, which not directly causes a rise in rDNA recombination and possible will increase the manufacturing of extrachromosomal rDNA circles.
The quick life span of a sir2 mutant additionally reveals a direct failure to repress recombination generated by the Fob1p-mediated replication block within the rDNA. Sir2p is a limiting element in selling yeast longevity, and rising the gene dosage extends the life span in wild-type cells. A attainable position of the conserved SIR2 in mammalian ageing is mentioned.
Calorie restriction extends life-span in all kinds of organisms. Although it has been steered that calorie restriction may match by lowering the degrees of reactive oxygen species produced throughout respiration, the mechanism by which this routine slows ageing is unsure. Here, we mimicked calorie restriction in yeast by physiological or genetic means and confirmed a considerable extension in life-span. This extension was not noticed in strains mutant for SIR2 (which encodes the silencing protein Sir2p) or NPT1 (a gene in a pathway within the synthesis of NAD, the oxidized type of nicotinamide adenine dinucleotide). These findings counsel that the elevated longevity induced by calorie restriction requires the activation of Sir2p by NAD.
The Drosophila melanogaster gene chico encodes an insulin receptor substrate that features in an insulin/insulin-like development issue (IGF) signaling pathway. In the nematode Caenorhabditis elegans, insulin/IGF signaling regulates grownup longevity. We discovered that mutation of chico extends fruit fly median life-span by as much as 48% in homozygotes and 36% in heterozygotes. Extension of life-span was not a results of impaired oogenesis in chico females, nor was it persistently correlated with elevated stress resistance. The dwarf phenotype of chico homozygotes was additionally pointless for extension of life-span. The position of insulin/IGF signaling in regulating animal ageing is due to this fact evolutionarily conserved.
Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors.

Autophagy and ageing.

 

To decide the position of reactive oxygen species in mammalian longevity, we generated transgenic mice that overexpress human catalase localized to the peroxisome, the nucleus, or mitochondria (MCAT). Median and most life spans had been maximally elevated (averages of 5 months and 5.5 months, respectively) in MCAT animals. Cardiac pathology and cataract improvement had been delayed, oxidative harm was diminished, H2O2 manufacturing and H2O2-induced aconitase inactivation had been attenuated, and the event of mitochondrial deletions was diminished. These outcomes help the free radical concept of ageing and reinforce the significance of mitochondria as a supply of those radicals.

Genetic inhibition of autophagy induces degenerative modifications in mammalian tissues that resemble these related to ageing, and regular and pathological ageing are sometimes related to a diminished autophagic potential. Pharmacological or genetic manipulations that improve life span in mannequin organisms typically stimulate autophagy, and its inhibition compromises the longevity-promoting results of caloric restriction, Sirtuin 1 activation, inhibition of insulin/insulin development issue signaling, or the administration of rapamycin, resveratrol, or spermidine.

Rat LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS061441-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS061441-48StripWells 48-Strip-Wells
EUR 550

Rat LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS061441-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS061441-96StripWells 96-Strip-Wells
EUR 765

Duck LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS104513-INQUIRE INQUIRE Ask for price

Cavy LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS088865-INQUIRE INQUIRE Ask for price

Fish LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS094610-INQUIRE INQUIRE Ask for price

Goat LAG1 Longevity Assurance Homolog 2 ELISA Kit
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Sheep LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS069851-10x96StripWells 10x96-Strip-Wells
EUR 6725

Sheep LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS069851-48StripWells 48-Strip-Wells
EUR 550

Sheep LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS069851-5x96StripWells 5x96-Strip-Wells
EUR 3420

Sheep LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS069851-96StripWells 96-Strip-Wells
EUR 765

Human LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS075268-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS075268-48StripWells 48-Strip-Wells
EUR 550

Human LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS075268-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS075268-96StripWells 96-Strip-Wells
EUR 765

Horse LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS078334-10x96StripWells 10x96-Strip-Wells
EUR 6725

Horse LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS078334-48StripWells 48-Strip-Wells
EUR 550

Horse LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS078334-5x96StripWells 5x96-Strip-Wells
EUR 3420

Horse LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS078334-96StripWells 96-Strip-Wells
EUR 765

Goose LAG1 Longevity Assurance Homolog 2 ELISA Kit
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Camel LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS081926-10x96StripWells 10x96-Strip-Wells
EUR 6725

Camel LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS081926-48StripWells 48-Strip-Wells
EUR 550

Camel LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS081926-5x96StripWells 5x96-Strip-Wells
EUR 3420

Camel LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS081926-96StripWells 96-Strip-Wells
EUR 765

Mouse LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS059479-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS059479-48StripWells 48-Strip-Wells
EUR 550

Mouse LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS059479-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS059479-96StripWells 96-Strip-Wells
EUR 765

Bovine LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS091805-10x96StripWells 10x96-Strip-Wells
EUR 6725

Bovine LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS091805-48StripWells 48-Strip-Wells
EUR 550

Bovine LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS091805-5x96StripWells 5x96-Strip-Wells
EUR 3420

Bovine LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS091805-96StripWells 96-Strip-Wells
EUR 765

Canine LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS065370-10x96StripWells 10x96-Strip-Wells
EUR 6725

Canine LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS065370-48StripWells 48-Strip-Wells
EUR 550

Canine LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS065370-5x96StripWells 5x96-Strip-Wells
EUR 3420

Canine LAG1 Longevity Assurance Homolog 2 ELISA Kit
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Pigeon LAG1 Longevity Assurance Homolog 2 ELISA Kit
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Rabbit LAG1 Longevity Assurance Homolog 2 ELISA Kit
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Monkey LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS049372-10x96StripWells 10x96-Strip-Wells
EUR 6725

Monkey LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS049372-48StripWells 48-Strip-Wells
EUR 550

Monkey LAG1 Longevity Assurance Homolog 2 ELISA Kit
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EUR 3420

Monkey LAG1 Longevity Assurance Homolog 2 ELISA Kit
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Donkey LAG1 Longevity Assurance Homolog 2 ELISA Kit
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Human LASS2 (Longevity Assurance Homolog 2) ELISA Kit
MBS8806191-10x96StripWells 10x96-Strip-Wells
EUR 3130

Human LASS2 (Longevity Assurance Homolog 2) ELISA Kit
MBS8806191-48StripWells 48-Strip-Wells
EUR 350

Human LASS2 (Longevity Assurance Homolog 2) ELISA Kit
MBS8806191-5x96StripWells 5x96-Strip-Wells
EUR 1710

Human LASS2 (Longevity Assurance Homolog 2) ELISA Kit
MBS8806191-96StripWells 96-Strip-Wells
EUR 445

Porcine LAG1 Longevity Assurance Homolog 2 ELISA Kit
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EUR 6725

Porcine LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS106708-48StripWells 48-Strip-Wells
EUR 550

Porcine LAG1 Longevity Assurance Homolog 2 ELISA Kit
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EUR 3420

Porcine LAG1 Longevity Assurance Homolog 2 ELISA Kit
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Chicken LAG1 Longevity Assurance Homolog 2 ELISA Kit
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Hamster LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS072334-10x96StripWells 10x96-Strip-Wells
EUR 6725

Hamster LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS072334-48StripWells 48-Strip-Wells
EUR 550

Hamster LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS072334-5x96StripWells 5x96-Strip-Wells
EUR 3420

Hamster LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS072334-96StripWells 96-Strip-Wells
EUR 765

Human Longevity Assurance Homolog 2 (CERS2) ELISA Kit
abx388232-96tests 96 tests
EUR 1093.2

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
DLR-LASS2-Hu 96T
EUR 505
Description: tissue homogenates, cell lysates or other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
DLR-LASS2-Hu-48T 48T
EUR 664.8
Description: A sandwich quantitative ELISA assay kit for detection of Human Longevity Assurance Homolog 2 (LASS2) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
DLR-LASS2-Hu-96T 96T
EUR 870
Description: A sandwich quantitative ELISA assay kit for detection of Human Longevity Assurance Homolog 2 (LASS2) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
DL-LASS2-Hu 96T
EUR 481
Description: tissue homogenates, cell lysates or other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKU05672-48T 48T
EUR 610.82

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKU05672-5x96T 5x96T
EUR 4144.85

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKU05672-96T 96T
EUR 872.6

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EK15188 96Т
EUR 768

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKN46783-48T 48T
EUR 416.29

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKN46783-5x96T 5x96T
EUR 2824.83

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKN46783-96T 96T
EUR 594.7

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS2000156-10x96StripWells 10x96-Strip-Wells
EUR 5770

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS2000156-24StripWells 24-Strip-Wells
EUR 380

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS2000156-48StripWells 48-Strip-Wells
EUR 585

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS2000156-5x96StripWells 5x96-Strip-Wells
EUR 3160

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS2000156-96StripWells 96-Strip-Wells
EUR 780

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS4500690-10x96Tests 10x96Tests
EUR 5670

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS4500690-48Tests 48Tests
EUR 490

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS4500690-5x96Tests 5x96Tests
EUR 2900

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS4500690-96Test 96Test
EUR 650

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS456293-10x96StripWells 10x96-Strip-Wells
EUR 5440

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS456293-48StripWells 48-Strip-Wells
EUR 475

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS456293-5x96StripWells 5x96-Strip-Wells
EUR 2785

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS456293-96StripWells 96-Strip-Wells
EUR 625

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS2707162-10x96StripWells 10x96-Strip-Wells
EUR 3430

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS2707162-24StripWells 24-Strip-Wells
EUR 260

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS2707162-48StripWells 48-Strip-Wells
EUR 350

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS2707162-5x96StripWells 5x96-Strip-Wells
EUR 1780

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS2707162-96StripWells 96-Strip-Wells
EUR 450

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RDR-LASS2-Hu-48T 48T
EUR 544
Description: sandwich

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RDR-LASS2-Hu-48Tests 48 Tests
EUR 706.8

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RDR-LASS2-Hu-96T 96T
EUR 777
Description: sandwich

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RDR-LASS2-Hu-96Tests 96 Tests
EUR 984

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
SEP312Hu-10x96wellstestplate 10x96-wells test plate
EUR 6227.58
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
SEP312Hu-1x48wellstestplate 1x48-wells test plate
EUR 618.04
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
SEP312Hu-1x96wellstestplate 1x96-wells test plate
EUR 831.48
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
SEP312Hu-5x96wellstestplate 5x96-wells test plate
EUR 3381.66
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
4-SEP312Hu
  • Ask for price
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  • Ask for price
  • 1 plate of 96 wells
  • 5 plates of 96 wells
  • 10 plates of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Longevity Assurance Homolog 2 (LASS2) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RD-LASS2-Hu-48T 48T
EUR 518
Description: sandwich

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RD-LASS2-Hu-48Tests 48 Tests
EUR 675.6

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RD-LASS2-Hu-96T 96T
EUR 740
Description: sandwich

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RD-LASS2-Hu-96Tests 96 Tests
EUR 939.6

LASS2 (Longevity Assurance Homolog 2)
MBS396467-005mg 0.05mg
EUR 250

LASS2 (Longevity Assurance Homolog 2)
MBS396467-5x005mg 5x0.05mg
EUR 975

Cat LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS108523-INQUIRE INQUIRE Ask for price

Cat LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS068990-INQUIRE INQUIRE Ask for price

Cat LAG1 Longevity Assurance Homolog 3 ELISA Kit
MBS073954-INQUIRE INQUIRE Ask for price

Cat LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS055496-INQUIRE INQUIRE Ask for price

Rat LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS060489-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS060489-48StripWells 48-Strip-Wells
EUR 550

Rat LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS060489-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS060489-96StripWells 96-Strip-Wells
EUR 765

Rat LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS052400-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS052400-48StripWells 48-Strip-Wells
EUR 550

Rat LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS052400-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS052400-96StripWells 96-Strip-Wells
EUR 765

Rat LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS053900-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS053900-48StripWells 48-Strip-Wells
EUR 550

Rat LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS053900-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS053900-96StripWells 96-Strip-Wells
EUR 765

Cat LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS050986-INQUIRE INQUIRE Ask for price

Rat LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS057368-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS057368-48StripWells 48-Strip-Wells
EUR 550

Rat LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS057368-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS057368-96StripWells 96-Strip-Wells
EUR 765

Rat LAG1 Longevity Assurance Homolog 3 ELISA Kit
MBS048358-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat LAG1 Longevity Assurance Homolog 3 ELISA Kit
MBS048358-48StripWells 48-Strip-Wells
EUR 550

Rat LAG1 Longevity Assurance Homolog 3 ELISA Kit
MBS048358-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat LAG1 Longevity Assurance Homolog 3 ELISA Kit
MBS048358-96StripWells 96-Strip-Wells
EUR 765

Fish LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS085893-INQUIRE INQUIRE Ask for price

Cavy LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS071049-INQUIRE INQUIRE Ask for price

Cavy LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS074625-INQUIRE INQUIRE Ask for price

Cavy LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS066331-INQUIRE INQUIRE Ask for price

Goat LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS073315-INQUIRE INQUIRE Ask for price

Cavy LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS076246-INQUIRE INQUIRE Ask for price

Goat LAG1 Longevity Assurance Homolog 6 ELISA Kit
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Duck LAG1 Longevity Assurance Homolog 5 ELISA Kit
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Duck LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS058160-INQUIRE INQUIRE Ask for price

Here, we talk about the possible trigger and impact relationship between perturbed autophagy and ageing, in addition to attainable molecular mechanisms which will mediate the anti-ageing results of autophagy.