HMI-S201

We estimated the prevalence and correlates of mild cognitive impairment (MCI) among middle-aged and older diverse Hispanics/Latinos.Middle-aged and older diverse Hispanics/Latinos enrolled (n = 6377; 50-86 years) in this multisite prospective cohort study were evaluated for MCI using the National Institute on Aging-Alzheimer’s Association diagnostic criteria.

HMI ORF Vector (Human) (pORF)

ORF021007 1.0 ug DNA Ask for price

HMI sgRNA CRISPR Lentivector set (Human)

K0974301 3 x 1.0 ug
EUR 406.8

HMI 3'UTR GFP Stable Cell Line

TU060007 1.0 ml
EUR 2799.6

HMI Protein Vector (Human) (pPM-C-HA)

PV084027 500 ng Ask for price

HMI Protein Vector (Human) (pPB-C-His)

PV084025 500 ng Ask for price

HMI Protein Vector (Human) (pPB-N-His)

PV084026 500 ng Ask for price

HMI Protein Vector (Human) (pPM-C-His)

PV084028 500 ng Ask for price

HMI 3'UTR Luciferase Stable Cell Line

TU010007 1.0 ml
EUR 2799.6

HMI sgRNA CRISPR Lentivector (Human) (Target 1)

K0974302 1.0 ug DNA
EUR 184.8

HMI sgRNA CRISPR Lentivector (Human) (Target 2)

K0974303 1.0 ug DNA
EUR 184.8

HMI sgRNA CRISPR Lentivector (Human) (Target 3)

K0974304 1.0 ug DNA
EUR 184.8

HMI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV728375 1.0 ug DNA Ask for price

HMI Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC)

LV728379 1.0 ug DNA Ask for price

HMI Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV728380 1.0 ug DNA Ask for price

HMI sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K0974305 3 x 1.0 ug
EUR 451.2

HMI sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K0974306 1.0 ug DNA
EUR 200.4

HMI sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

K0974307 1.0 ug DNA
EUR 200.4

HMI sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

K0974308 1.0 ug DNA
EUR 200.4

HMI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA)

LV728376 1.0 ug DNA Ask for price

HMI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV728377 1.0 ug DNA Ask for price

HMI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

LV728378 1.0 ug DNA Ask for price

Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast) HMI1 Polyclonal Antibody

MBS7189694-INQUIRE INQUIRE Ask for price

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (AP)

MBS6132326-01mL 0.1(mL
EUR 875

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (AP)

MBS6132326-5x01mL 5x0.1mL
EUR 3800

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) APC

MBS6137629-01mL 0.1(mL
EUR 875

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) APC

MBS6137629-5x01mL 5x0.1mL
EUR 3800

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (AP)

MBS6385478-01mL 0.1mL
EUR 920

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (AP)

MBS6385478-5x01mL 5x0.1mL
EUR 3990

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) APC

MBS6385479-01mL 0.1mL
EUR 920

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) APC

MBS6385479-5x01mL 5x0.1mL
EUR 3990

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (HRP)

MBS6385482-01mL 0.1mL
EUR 920

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (HRP)

MBS6385482-5x01mL 5x0.1mL
EUR 3990

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (PE)

MBS6385488-01mL 0.1mL
EUR 920

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (PE)

MBS6385488-5x01mL 5x0.1mL
EUR 3990

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (PE)

MBS6158841-01mL 0.1(mL
EUR 875

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (PE)

MBS6158841-5x01mL 5x0.1mL
EUR 3800

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (HRP)

MBS6153538-01mL 0.1(mL
EUR 875

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (HRP)

MBS6153538-5x01mL 5x0.1mL
EUR 3800

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (FITC)

MBS6148235-01mL 0.1(mL
EUR 875

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (FITC)

MBS6148235-5x01mL 5x0.1mL
EUR 3800

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (FITC)

MBS6385481-01mL 0.1mL
EUR 920

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (FITC)

MBS6385481-5x01mL 5x0.1mL
EUR 3990

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (Biotin)

MBS6142932-01mL 0.1(mL
EUR 875

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (Biotin)

MBS6142932-5x01mL 5x0.1mL
EUR 3800

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (Biotin)

MBS6385480-01mL 0.1mL
EUR 920

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (Biotin)

MBS6385480-5x01mL 5x0.1mL
EUR 3990

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (MaxLight 550)

MBS6212539-01mL 0.1(mL
EUR 875

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (MaxLight 550)

MBS6212539-5x01mL 5x0.1mL
EUR 3800

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (MaxLight 405)

MBS6191189-01mL 0.1(mL
EUR 875

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (MaxLight 405)

MBS6191189-5x01mL 5x0.1mL
EUR 3800

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (MaxLight 750)

MBS6233889-01mL 0.1(mL
EUR 875

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (MaxLight 750)

MBS6233889-5x01mL 5x0.1mL
EUR 3800

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (MaxLight 490)

MBS6201864-01mL 0.1(mL
EUR 875

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (MaxLight 490)

MBS6201864-5x01mL 5x0.1mL
EUR 3800

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (MaxLight 405)

MBS6385483-01mL 0.1mL
EUR 920

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (MaxLight 405)

MBS6385483-5x01mL 5x0.1mL
EUR 3990

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (MaxLight 490)

MBS6385484-01mL 0.1mL
EUR 920

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (MaxLight 490)

MBS6385484-5x01mL 5x0.1mL
EUR 3990

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (MaxLight 550)

MBS6385485-01mL 0.1mL
EUR 920

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (MaxLight 550)

MBS6385485-5x01mL 5x0.1mL
EUR 3990

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (MaxLight 650)

MBS6385486-01mL 0.1mL
EUR 920

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (MaxLight 650)

MBS6385486-5x01mL 5x0.1mL
EUR 3990

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (MaxLight 750)

MBS6385487-01mL 0.1mL
EUR 920

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (MaxLight 750)

MBS6385487-5x01mL 5x0.1mL
EUR 3990

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (MaxLight 650)

MBS6223214-01mL 0.1(mL
EUR 875

MIS12 (Protein MIS12 Homolog, 2510025F08Rik, hMis12, hMIS12, KNTC2AP, MGC2488, MTW1) (MaxLight 650)

MBS6223214-5x01mL 5x0.1mL
EUR 3800

HMI1 Antibody

CSB-PA612273XA01SVG-02mg 0.2mg Ask for price
Description: Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) HMI1 protein

HMI1 Antibody

CSB-PA612273XA01SVG-10mg 10mg Ask for price
Description: Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) HMI1 protein

Recombinant Saccharomyces cerevisiae ATP-dependent DNA helicase HMI1, mitochondrial (HMI1) , partial

MBS1281218-INQUIRE INQUIRE Ask for price

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (AP)

MBS6426749-01mL 0.1mL
EUR 950

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (AP)

MBS6426749-5x01mL 5x0.1mL
EUR 4120

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (PE)

MBS6426759-01mL 0.1mL
EUR 950

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (PE)

MBS6426759-5x01mL 5x0.1mL
EUR 4120

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (APC)

MBS6426750-01mL 0.1mL
EUR 950

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (APC)

MBS6426750-5x01mL 5x0.1mL
EUR 4120

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (HRP)

MBS6426753-01mL 0.1mL
EUR 950

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (HRP)

MBS6426753-5x01mL 5x0.1mL
EUR 4120

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (FITC)

MBS6426752-01mL 0.1mL
EUR 950

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (FITC)

MBS6426752-5x01mL 5x0.1mL
EUR 4120

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (Biotin)

MBS6426751-01mL 0.1mL
EUR 950

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (Biotin)

MBS6426751-5x01mL 5x0.1mL
EUR 4120

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (MaxLight 405)

MBS6426754-01mL 0.1mL
EUR 950

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (MaxLight 405)

MBS6426754-5x01mL 5x0.1mL
EUR 4120

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (MaxLight 490)

MBS6426755-01mL 0.1mL
EUR 950

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (MaxLight 490)

MBS6426755-5x01mL 5x0.1mL
EUR 4120

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (MaxLight 550)

MBS6426756-01mL 0.1mL
EUR 950

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (MaxLight 550)

MBS6426756-5x01mL 5x0.1mL
EUR 4120

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (MaxLight 650)

MBS6426757-01mL 0.1mL
EUR 950

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (MaxLight 650)

MBS6426757-5x01mL 5x0.1mL
EUR 4120

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (MaxLight 750)

MBS6426758-01mL 0.1mL
EUR 950

MINK1 (Misshapen-like Kinase 1, B55, ZC3, MINK, YSK2, hMINK, MAP4K6, hMINKbeta) (MaxLight 750)

MBS6426758-5x01mL 5x0.1mL
EUR 4120

AQP4 (Aquaporin 4, MIWC, HMIWC2) (AP)

MBS6406982-01mL 0.1mL
EUR 950

AQP4 (Aquaporin 4, MIWC, HMIWC2) (AP)

MBS6406982-5x01mL 5x0.1mL
EUR 4120

AQP4 (Aquaporin 4, MIWC, HMIWC2) (PE)

MBS6406992-01mL 0.1mL
EUR 950

AQP4 (Aquaporin 4, MIWC, HMIWC2) (PE)

MBS6406992-5x01mL 5x0.1mL
EUR 4120

HM13-IT1 ORF Vector (Human) (pORF)

ORF020821 1.0 ug DNA Ask for price

S18-000003

555361 25.0mg
EUR 350

S18-000003

HY-119366 10 mg
EUR 1461.06
Description: S18-000003 is a potent, selective and orally active inhibitor of retinoic acid receptor-related orphan receptor-gamma-t (RORγt), with an IC50 of 10 μM). S18-000003 can be used for the research of psoriasis with low risk of thymic aberrations[1][2].

S18-000003

MBS3843562-10mg 10mg
EUR 810

S18-000003

MBS3843562-50mg 50mg
EUR 2370

S18-000003

MBS3843562-5mg 5mg
EUR 465

S18-000003

MBS3843562-5x50mg 5x50mg
EUR 10655

S18-000003

MBS5764698-10mg 10mg
EUR 405

S18-000003

MBS5764698-1mg 1mg
EUR 195

S18-000003

MBS5764698-25mg 25mg
EUR 730

S18-000003

MBS5764698-50mg 50mg
EUR 1125

S18-000003

MBS5764698-5mg 5mg
EUR 285

S18-000003

T16832-10mg 10mg Ask for price
Description: S18-000003

S18-000003

T16832-1g 1g Ask for price
Description: S18-000003

S18-000003

T16832-1mg 1mg Ask for price
Description: S18-000003

S18-000003

T16832-50mg 50mg Ask for price
Description: S18-000003

S18-000003

T16832-5mg 5mg Ask for price
Description: S18-000003

AQP4 (Aquaporin 4, MIWC, HMIWC2) (APC)

MBS6406983-01mL 0.1mL
EUR 950

AQP4 (Aquaporin 4, MIWC, HMIWC2) (APC)

MBS6406983-5x01mL 5x0.1mL
EUR 4120

AQP4 (Aquaporin 4, MIWC, HMIWC2) (HRP)

MBS6406986-01mL 0.1mL
EUR 950

AQP4 (Aquaporin 4, MIWC, HMIWC2) (HRP)

MBS6406986-5x01mL 5x0.1mL
EUR 4120

Gynkotek 320 340S 160 170S Lamp - EACH

LMP2016 EACH
EUR 591.3

Mixture of S077210 (150mL of 1mg/mL S077210 in a 0.9% (Sodium Chloride) NaCl solution)

TRC-CMIX016-150ML 150 mL Ask for price

S100 beta (S100 Calcium Binding Protein B, S100B, NEF, S100, S100beta) (AP)

MBS6436528-01mL 0.1mL
EUR 950

S100 beta (S100 Calcium Binding Protein B, S100B, NEF, S100, S100beta) (AP)

MBS6436528-5x01mL 5x0.1mL
EUR 4120

S100 beta (S100 Calcium Binding Protein B, S100B, NEF, S100, S100beta) (PE)

MBS6436538-01mL 0.1mL
EUR 950

S100 beta (S100 Calcium Binding Protein B, S100B, NEF, S100, S100beta) (PE)

MBS6436538-5x01mL 5x0.1mL
EUR 4120

AQP4 (Aquaporin 4, MIWC, HMIWC2) (FITC)

MBS6406985-01mL 0.1mL
EUR 950

AQP4 (Aquaporin 4, MIWC, HMIWC2) (FITC)

MBS6406985-5x01mL 5x0.1mL
EUR 4120

S100 beta (S100 Calcium Binding Protein B, S100B, NEF, S100, S100beta) (APC)

MBS6436529-01mL 0.1mL
EUR 950

S100 beta (S100 Calcium Binding Protein B, S100B, NEF, S100, S100beta) (APC)

MBS6436529-5x01mL 5x0.1mL
EUR 4120

S100 beta (S100 Calcium Binding Protein B, S100B, NEF, S100, S100beta) (HRP)

MBS6436532-01mL 0.1mL
EUR 950

S100 beta (S100 Calcium Binding Protein B, S100B, NEF, S100, S100beta) (HRP)

MBS6436532-5x01mL 5x0.1mL
EUR 4120

S100 beta (S100 Calcium Binding Protein B, S100B, NEF, S100, S100beta) (FITC)

MBS6436531-01mL 0.1mL
EUR 950

S100 beta (S100 Calcium Binding Protein B, S100B, NEF, S100, S100beta) (FITC)

MBS6436531-5x01mL 5x0.1mL
EUR 4120

S07-2010

HY-150644 10 mg
EUR 573.6
Description: S07-2010 is a potent pan-AKR1C (aldo-keto reductase family 1 member C) inhibitor, with IC50 values of 0.19, 0.36, 0.47, and 0.73 μM for AKR1C3, AKR1C4, AKR1C1 and AKR1C2, respectively. S07-2010 induces apoptosis in A549/DDP cells. S07-2010 strengthens the cytotoxicity of chemotherapeutic agents in drug-resistant cells. S07-2010 significantly inhibits the proliferation of drug-resistant cells[1].

S07-2009

HY-150646 Get quote Ask for price
Description: S07-2009 is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 0.20 μM[1].

S07-2008

HY-150648 Get quote Ask for price
Description: S07-2008 is a selective aldo-keto reductase family 1 member C3 (AKR1C3) inhibitor with an IC50 of 0.16 μM. S07-2008 shows anticancer activities[1].

S07-2001

HY-150650 Get quote Ask for price
Description: S07-2001 is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 2.08 μM. S07-2001 enhances the activity of Doxorubicin against cancer cells. S07-2001 has potential as a chemotherapeutic potentiator for cancer agent resistance[1].

S19-1035

HY-152189 10 mg
EUR 367.97
Description: S19-1035 is a highly potent and specific aldo-keto reductase 1C3 (AKR1C3) inhibitor. S19-1035 inhibits AKR1C3 with an IC50 value of 3.04 nM. S19-1035 can be used for the research of tumor[1].

S07-1066

HY-155035 1 mg
EUR 914.52
Description: S07-1066 is an aldo-keto reductase 1C3 (AKR1C3) inhibitor, synergizing doxorubicin (DOX) cytotoxicity. S07-1066 selectively blocks AKR1C3-mediated reduction of DOX, and reverses the DOX resistance in overexpressing AKR1C3 cells[1].

S217879

HY-156065 Get quote Ask for price
Description: S217879 is a highly potent and selective NRF2 activator. S217879 disrupts the KEAP1-NRF2 interaction leading to robust NRF2 pathway activation. S217879 can be used for non-alcoholic steatohepatitis (NASH) research[1].

S116836

HY-123450 10 mg
EUR 3246.8
Description: S116836, a potent, orally active BCR-ABL tyrosine kinase inhibitor, blocks both wild-type as well as T315I Bcr-Abl. S116836 arrests the cells in the G0/G1 phase of cell cycle, induces apoptosis, increases ROS production, and decreases GSH production in BaF3/WT and BaF3/T315I cells. S116836 also inhibits SRC, LYN, HCK, LCK and BLK, and receptor tyrosine kinases such as FLT3, TIE2, KIT, PDGFR-β. Antitumor activies[1][2][3]. S116836 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

S-777469

HY-145153 10 mg
EUR 2110.42
Description: S-777469 is a selective and orally available cannabinoid type 2 receptor (CB2) agonist with a Ki of 36 nM. S-777469 significantly suppresses compound 48/80-induced scratching behavior in mice in a dose-dependent manner. S-777469 produces its antipruritic effects by inhibiting itch signal transmission through CB2 agonism[1][2].

S-23906-1

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EUR 915

S-23906-1

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S116836

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S116836

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EUR 2075

S116836

MBS5774496-5x25mg 5x25mg
EUR 9185

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T34474-50mg 50mg Ask for price
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T34474-5mg 5mg Ask for price
Description: S-23906-1

The overall MCI prevalence was 9.8%, which varied between Hispanic/Latino groups. Older age, high cardiovascular disease (CVD) risk, and elevated depressive symptoms were significant correlates of MCI prevalence. Apolipoprotein E4 (APOE) and APOE2 were not significantly associated with MCI.MCI prevalence varied among Hispanic/Latino backgrounds, but not as widely as reported in the previous studies.

CVD risk and depressive symptoms were associated with increased MCI, whereas APOE4 was not, suggesting alternative etiologies for MCI among diverse Hispanics/Latinos. Our findings suggest that mitigating CVD risk factors may offer important pathways to understanding and reducing MCI and possibly dementia among diverse Hispanics/Latinos.