Tag: gelsolin

SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer’s disease and amyotrophic lateral sclerosis.

SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis.

A progressive lack of neurons with age underlies quite a lot of debilitating neurological issues, together with Alzheimer’s disease (AD) and amyotrophic lateral sclerosis (ALS), but few efficient therapies are at present accessible. The SIR2 gene promotes longevity in quite a lot of organisms and might underlie the well being advantages of caloric restriction, a weight-reduction plan that delays ageing and neurodegeneration in mammals. Here, we report {that a} human homologue of SIR2, SIRT1, is upregulated in mouse models for AD, ALS and in main neurons challenged with neurotoxic insults.

In cell-based models for AD/tauopathies and ALS, SIRT1 and resveratrol, a SIRT1-activating molecule, each promote neuronal survival. In the inducible p25 transgenic mouse, a mannequin of AD and tauopathies, resveratrol lowered neurodegeneration in the hippocampus, prevented studying impairment, and decreased the acetylation of the recognized SIRT1 substrates PGC-1alpha and p53. Furthermore, injection of SIRT1 lentivirus in the hippocampus of p25 transgenic mice conferred vital safety against neurodegeneration. Thus, SIRT1 constitutes a singular molecular hyperlink between ageing and human neurodegenerative issues and supplies a promising avenue for therapeutic intervention.

Telomere upkeep is assumed to play a task in signaling mobile senescence; nevertheless, a hyperlink with organismal ageing processes has not been established. The telomerase null mouse supplies a possibility to grasp the consequences related to vital telomere shortening on the organismal degree. We studied quite a lot of physiological processes in an ageing cohort of mTR-/- mice. Loss of telomere perform didn’t elicit a full spectrum of classical pathophysiological signs of ageing.

However, age-dependent telomere shortening and accompanying genetic instability have been related to shortened life span in addition to a lowered capability to reply to stresses comparable to wound therapeutic and hematopoietic ablation. In addition, we discovered an elevated incidence of spontaneous malignancies. These findings show a vital function for telomere size in the general health, reserve, and properly being of the ageing organism.

Direct inhibition of the longevity-promoting issue SKN-1 by insulin-like signaling in C. elegans.

 

Insulin/IGF-1-like signaling (IIS) is central to progress and metabolism and has a conserved function in ageing. In C. elegans, reductions in IIS improve stress resistance and longevity, results that require the IIS-inhibited FOXO protein DAF-16. The C. elegans transcription issue SKN-1 additionally defends against oxidative stress by mobilizing the conserved part 2 detoxing response. Here we present that IIS not solely opposes DAF-16 but additionally straight inhibits SKN-1 in parallel.

The IIS kinases AKT-1, -2, and SGK-1 phosphorylate SKN-1, and lowered IIS results in constitutive SKN-1 nuclear accumulation in the gut and SKN-1 goal gene activation. SKN-1 contributes to the elevated stress tolerance and longevity ensuing from lowered IIS and delays ageing when expressed transgenically. Furthermore, SKN-1 that’s constitutively lively will increase life span independently of DAF-16. Our findings point out that the transcription community regulated by SKN-1 promotes longevity and is a crucial direct goal of IIS.

Aberrant protein aggregation is a typical characteristic of late-onset neurodegenerative ailments, together with Alzheimer’s disease, which is related to the misassembly of the Abeta(1-42) peptide. Aggregation-mediated Abeta(1-42) toxicity was lowered in Caenorhabditis elegans when ageing was slowed by decreased insulin/insulin progress factor-1-like signaling (IIS).

The downstream transcription elements, warmth shock issue 1, and DAF-16 regulate opposing disaggregation and aggregation actions to advertise mobile survival in response to constitutive poisonous protein aggregation. Because the IIS pathway is central to the regulation of longevity and youthfulness in worms, flies, and mammals, these outcomes counsel a mechanistic hyperlink between the ageing course of and aggregation-mediated proteotoxicity.

SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis.

SIRT6 hyperlinks histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span.

Members of the sirtuin (SIRT) household of NAD-dependent deacetylases promote longevity in a number of organisms. Deficiency of mammalian SIRT6 results in shortened life span and an ageing-like phenotype in mice, however the underlying molecular mechanisms are unclear. Here we present that SIRT6 capabilities at chromatin to attenuate NF-kappaB signaling.

SIRT6 interacts with the NF-kappaB RELA subunit and deacetylates histone H3 lysine 9 (H3K9) at NF-kappaB goal gene promoters. In SIRT6-deficient cells, hyperacetylation of H3K9 at these goal promoters is related to elevated RELA promoter occupancy and enhanced NF-kappaB-dependent modulation of gene expression, apoptosis, and mobile senescence.

Computational genomics analyses revealed elevated exercise of NF-kappaB-driven gene expression packages in a number of Sirt6-deficient tissues in vivo. Moreover, haploinsufficiency of RelA rescues the early lethality and degenerative syndrome of Sirt6-deficient mice. We suggest that SIRT6 attenuates NF-kappaB signaling through H3K9 deacetylation at chromatin, and hyperactive NF-kappaB signaling might contribute to untimely and regular ageing.

The life span of C. elegans will be elevated through lowered perform of the mitochondria; nevertheless, the extent to which mitochondrial alteration in a single, distinct tissue might affect ageing in the entire organism stays unknown. We addressed this query by asking whether or not manipulations to ETC perform can modulate ageing in a cell-non-autonomous style.

Longevity Assurance Homolog 2 (LASS2) Antibody
20-abx177383
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  • 200 ug
  • 1 mg

Longevity Assurance Homolog 2 (LASS2) Antibody
abx234705-100ug 100 ug
EUR 661.2

Human Longevity Assurance Homolog 2 ELISA Kit
IHULASS2KT each
EUR 799
Description: Human Longevity Assurance Homolog 2 ELISA Kit

LAG1 Longevity Assurance Homolog 2 (LASS2) Antibody
abx019124-100ug 100 ug
EUR 410.4

Cat LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS071564-INQUIRE INQUIRE Ask for price

Rat LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS061441-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS061441-48StripWells 48-Strip-Wells
EUR 550

Rat LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS061441-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS061441-96StripWells 96-Strip-Wells
EUR 765

Longevity Assurance Homolog 6 (LASS6) Antibody
abx029719-400ul 400 ul
EUR 627.6

Duck LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS104513-INQUIRE INQUIRE Ask for price

Cavy LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS088865-INQUIRE INQUIRE Ask for price

Fish LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS094610-INQUIRE INQUIRE Ask for price

Goat LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS099334-INQUIRE INQUIRE Ask for price

Sheep LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS069851-10x96StripWells 10x96-Strip-Wells
EUR 6725

Sheep LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS069851-48StripWells 48-Strip-Wells
EUR 550

Sheep LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS069851-5x96StripWells 5x96-Strip-Wells
EUR 3420

Sheep LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS069851-96StripWells 96-Strip-Wells
EUR 765

Human LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS075268-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS075268-48StripWells 48-Strip-Wells
EUR 550

Human LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS075268-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS075268-96StripWells 96-Strip-Wells
EUR 765

Horse LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS078334-10x96StripWells 10x96-Strip-Wells
EUR 6725

Horse LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS078334-48StripWells 48-Strip-Wells
EUR 550

Horse LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS078334-5x96StripWells 5x96-Strip-Wells
EUR 3420

Horse LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS078334-96StripWells 96-Strip-Wells
EUR 765

Goose LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS078558-INQUIRE INQUIRE Ask for price

Camel LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS081926-10x96StripWells 10x96-Strip-Wells
EUR 6725

Camel LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS081926-48StripWells 48-Strip-Wells
EUR 550

Camel LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS081926-5x96StripWells 5x96-Strip-Wells
EUR 3420

Camel LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS081926-96StripWells 96-Strip-Wells
EUR 765

Mouse LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS059479-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS059479-48StripWells 48-Strip-Wells
EUR 550

Mouse LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS059479-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS059479-96StripWells 96-Strip-Wells
EUR 765

LASS5, CT (LAG1 Longevity Assurance Homolog 5)
MBS645096-005mg 0.05mg
EUR 745

LASS5, CT (LAG1 Longevity Assurance Homolog 5)
MBS645096-5x005mg 5x0.05mg
EUR 3195

Human Longevity Assurance Homolog 2 (CERS2) ELISA Kit
abx388232-96tests 96 tests
EUR 1093.2

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
DLR-LASS2-Hu 96T
EUR 505
Description: tissue homogenates, cell lysates or other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
DLR-LASS2-Hu-48T 48T
EUR 664.8
Description: A sandwich quantitative ELISA assay kit for detection of Human Longevity Assurance Homolog 2 (LASS2) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
DLR-LASS2-Hu-96T 96T
EUR 870
Description: A sandwich quantitative ELISA assay kit for detection of Human Longevity Assurance Homolog 2 (LASS2) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
DL-LASS2-Hu 96T
EUR 481
Description: tissue homogenates, cell lysates or other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKU05672-48T 48T
EUR 610.82

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKU05672-5x96T 5x96T
EUR 4144.85

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKU05672-96T 96T
EUR 872.6

Bovine LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS091805-10x96StripWells 10x96-Strip-Wells
EUR 6725

Bovine LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS091805-48StripWells 48-Strip-Wells
EUR 550

Bovine LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS091805-5x96StripWells 5x96-Strip-Wells
EUR 3420

Bovine LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS091805-96StripWells 96-Strip-Wells
EUR 765

Canine LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS065370-10x96StripWells 10x96-Strip-Wells
EUR 6725

Canine LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS065370-48StripWells 48-Strip-Wells
EUR 550

Canine LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS065370-5x96StripWells 5x96-Strip-Wells
EUR 3420

Canine LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS065370-96StripWells 96-Strip-Wells
EUR 765

Pigeon LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS060536-INQUIRE INQUIRE Ask for price

Rabbit LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS061006-INQUIRE INQUIRE Ask for price

Monkey LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS049372-10x96StripWells 10x96-Strip-Wells
EUR 6725

Monkey LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS049372-48StripWells 48-Strip-Wells
EUR 550

Monkey LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS049372-5x96StripWells 5x96-Strip-Wells
EUR 3420

Monkey LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS049372-96StripWells 96-Strip-Wells
EUR 765

Donkey LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS093961-INQUIRE INQUIRE Ask for price

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EK15188 96Т
EUR 768

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKN46783-48T 48T
EUR 416.29

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKN46783-5x96T 5x96T
EUR 2824.83

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKN46783-96T 96T
EUR 594.7

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS2000156-10x96StripWells 10x96-Strip-Wells
EUR 5770

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS2000156-24StripWells 24-Strip-Wells
EUR 380

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS2000156-48StripWells 48-Strip-Wells
EUR 585

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS2000156-5x96StripWells 5x96-Strip-Wells
EUR 3160

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS2000156-96StripWells 96-Strip-Wells
EUR 780

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS4500690-10x96Tests 10x96Tests
EUR 5670

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS4500690-48Tests 48Tests
EUR 490

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS4500690-5x96Tests 5x96Tests
EUR 2900

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS4500690-96Test 96Test
EUR 650

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS456293-10x96StripWells 10x96-Strip-Wells
EUR 5440

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS456293-48StripWells 48-Strip-Wells
EUR 475

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS456293-5x96StripWells 5x96-Strip-Wells
EUR 2785

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS456293-96StripWells 96-Strip-Wells
EUR 625

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS2707162-10x96StripWells 10x96-Strip-Wells
EUR 3430

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS2707162-24StripWells 24-Strip-Wells
EUR 260

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS2707162-48StripWells 48-Strip-Wells
EUR 350

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS2707162-5x96StripWells 5x96-Strip-Wells
EUR 1780

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
MBS2707162-96StripWells 96-Strip-Wells
EUR 450

Human LASS2 (Longevity Assurance Homolog 2) ELISA Kit
MBS8806191-10x96StripWells 10x96-Strip-Wells
EUR 3130

Human LASS2 (Longevity Assurance Homolog 2) ELISA Kit
MBS8806191-48StripWells 48-Strip-Wells
EUR 350

Human LASS2 (Longevity Assurance Homolog 2) ELISA Kit
MBS8806191-5x96StripWells 5x96-Strip-Wells
EUR 1710

Human LASS2 (Longevity Assurance Homolog 2) ELISA Kit
MBS8806191-96StripWells 96-Strip-Wells
EUR 445

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RDR-LASS2-Hu-48T 48T
EUR 544
Description: sandwich

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RDR-LASS2-Hu-48Tests 48 Tests
EUR 706.8

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RDR-LASS2-Hu-96T 96T
EUR 777
Description: sandwich

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RDR-LASS2-Hu-96Tests 96 Tests
EUR 984

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
SEP312Hu-10x96wellstestplate 10x96-wells test plate
EUR 6227.58
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
SEP312Hu-1x48wellstestplate 1x48-wells test plate
EUR 618.04
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
SEP312Hu-1x96wellstestplate 1x96-wells test plate
EUR 831.48
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
SEP312Hu-5x96wellstestplate 5x96-wells test plate
EUR 3381.66
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
4-SEP312Hu
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  • 1 plate of 96 wells
  • 5 plates of 96 wells
  • 10 plates of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Longevity Assurance Homolog 2 (LASS2) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RD-LASS2-Hu-48T 48T
EUR 518
Description: sandwich

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RD-LASS2-Hu-48Tests 48 Tests
EUR 675.6

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RD-LASS2-Hu-96T 96T
EUR 740
Description: sandwich

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RD-LASS2-Hu-96Tests 96 Tests
EUR 939.6

Porcine LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS106708-10x96StripWells 10x96-Strip-Wells
EUR 6725

Porcine LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS106708-48StripWells 48-Strip-Wells
EUR 550

Porcine LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS106708-5x96StripWells 5x96-Strip-Wells
EUR 3420

Porcine LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS106708-96StripWells 96-Strip-Wells
EUR 765

Chicken LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS067429-INQUIRE INQUIRE Ask for price

Hamster LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS072334-10x96StripWells 10x96-Strip-Wells
EUR 6725

Hamster LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS072334-48StripWells 48-Strip-Wells
EUR 550

Hamster LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS072334-5x96StripWells 5x96-Strip-Wells
EUR 3420

Hamster LAG1 Longevity Assurance Homolog 2 ELISA Kit
MBS072334-96StripWells 96-Strip-Wells
EUR 765

LASS1 (CerS1, LAG1, MGC90349, UOG1, LAG1 Longevity Assurance Homolog 1, Longevity Assurance Gene 1 Protein Homolog 1, Protein UOG-1)
MBS6005325-01mg 0.1(mg
EUR 630

LASS1 (CerS1, LAG1, MGC90349, UOG1, LAG1 Longevity Assurance Homolog 1, Longevity Assurance Gene 1 Protein Homolog 1, Protein UOG-1)
MBS6005325-5x01mg 5x0.1mg
EUR 2680

LASS1 (CerS1, LAG1, MGC90349, UOG1, LAG1 longevity assurance homolog 1, Longevity assurance gene 1 protein homolog 1, Protein UOG-1)
MBS621361-01mg 0.1mg
EUR 655

LASS1 (CerS1, LAG1, MGC90349, UOG1, LAG1 longevity assurance homolog 1, Longevity assurance gene 1 protein homolog 1, Protein UOG-1)
MBS621361-5x01mg 5x0.1mg
EUR 2800

LAG1 Longevity Assurance Homolog 4 (LASS4) Antibody
abx013801-100l 100 µl
EUR 43.75

LAG1 Longevity Assurance Homolog 4 (LASS4) Antibody
20-abx013801
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  • 10 ug
  • 100 ug
  • 200 ug
  • 300 µg

LAG1 Longevity Assurance Homolog 4 (LASS4) Antibody
20-abx008040
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  • 30 ul
  • 100 ul
  • 200 ul

LAG1 Longevity Assurance Homolog 3 (LASS3) Antibody
abx430427-200ul 200 ul
EUR 460.8

ELISA kit for Human LASS2 (Longevity Assurance Homolog 2)
ELK7214 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Longevity Assurance Homolog 2 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Cat LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS108523-INQUIRE INQUIRE Ask for price

Cat LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS068990-INQUIRE INQUIRE Ask for price

Cat LAG1 Longevity Assurance Homolog 3 ELISA Kit
MBS073954-INQUIRE INQUIRE Ask for price

Cat LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS055496-INQUIRE INQUIRE Ask for price

Rat LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS060489-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS060489-48StripWells 48-Strip-Wells
EUR 550

Rat LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS060489-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat LAG1 Longevity Assurance Homolog 4 ELISA Kit
MBS060489-96StripWells 96-Strip-Wells
EUR 765

Rat LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS052400-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS052400-48StripWells 48-Strip-Wells
EUR 550

Rat LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS052400-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS052400-96StripWells 96-Strip-Wells
EUR 765

Rat LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS053900-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS053900-48StripWells 48-Strip-Wells
EUR 550

Rat LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS053900-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat LAG1 Longevity Assurance Homolog 6 ELISA Kit
MBS053900-96StripWells 96-Strip-Wells
EUR 765

Cat LAG1 Longevity Assurance Homolog 1 ELISA Kit
MBS050986-INQUIRE INQUIRE Ask for price

Rat LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS057368-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS057368-48StripWells 48-Strip-Wells
EUR 550

Rat LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS057368-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat LAG1 Longevity Assurance Homolog 5 ELISA Kit
MBS057368-96StripWells 96-Strip-Wells
EUR 765

Rat LAG1 Longevity Assurance Homolog 3 ELISA Kit
MBS048358-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat LAG1 Longevity Assurance Homolog 3 ELISA Kit
MBS048358-48StripWells 48-Strip-Wells
EUR 550

Rat LAG1 Longevity Assurance Homolog 3 ELISA Kit
MBS048358-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat LAG1 Longevity Assurance Homolog 3 ELISA Kit
MBS048358-96StripWells 96-Strip-Wells
EUR 765

Human LAG1 longevity assurance homolog 2 (LASS2) ELISA Kit
AE35962HU-48T 48T
EUR 325
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 2 (LASS2) ELISA Kit
AE35962HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 2 (LASS2) ELISA Kit
AE35962HU-96T 96T
EUR 610
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 2 (LASS2) ELISA Kit
AE35962HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

We report that the alteration of mitochondrial perform in key tissues is crucial for establishing and sustaining a professionallongevity cue. We discover that regulators of mitochondrial stress responses are important and particular genetic necessities for the electron transport chain (ETC) longevity pathway. Strikingly, we discover that mitochondrial perturbation in one tissue is perceived and acted upon by the mitochondrial stress response pathway in a distal tissue.