TA-65 doesn’t enhance telomere size throughout post-natal growth in home sparrow chicks (Passer domesticus)

 

Telomeres, protecting caps on the finish of chromosomes, are sometimes positively associated to lifespan and are regarded as an necessary mechanism of organismal aging. To higher perceive the informal relationships between telomere size and longevity, it’s important to have the ability to experimentally manipulate telomere dynamics (size and loss price).

Previous research recommend that publicity to TA-65, an extract from the Chinese root Astragalus membranaceus, prompts telomerase, lengthens telomeres, will increase the expansion of keratin-based buildings, and boosts the immune system in adults. However, telomere loss is anticipated to be biggest throughout adolescence however whether or not TA-65 has related results throughout this life stage is at the moment unknown.

Here, we experimentally uncovered free-living home sparrow (Passer domesticus) chicks to TA-65 throughout post-natal growth and examined the results on telomere size and loss, progress of keratin-based buildings, and a measure of mobile immunity. Contrary to expectation, the expansion of keratin-based buildings was decreased in TA-65 chicks and in the second yr of the examine, chicks uncovered to TA-65 skilled extra telomere loss than controls.

Beneficial and Detrimental Effects of Reactive Oxygen Species on Lifespan: A Comprehensive Review of Comparative and Experimental Studies

Aging is the best danger issue for a mess of illnesses together with heart problems, neurodegeneration and most cancers. Despite many years of analysis devoted to understanding aging, the mechanisms underlying the aging course of stay incompletely understood. The widely-accepted free radical idea of aging (FRTA) proposes that the buildup of oxidative injury attributable to reactive oxygen species (ROS) is among the major causes of aging.

To outline the connection between ROS and aging, there have been two major approaches: comparative research that measure outcomes associated to ROS throughout species with totally different lifespans, and experimental research that modulate ROS ranges inside a single species utilizing both a genetic or pharmacologic strategy. Comparative research have proven that ranges of ROS and oxidative injury are inversely correlated with lifespan. While these research in basic help the FRTA, any such experiment can solely exhibit correlation, not causation.

Experimental research involving the manipulation of ROS ranges in mannequin organisms have typically proven that interventions that enhance ROS are inclined to lower lifespan, whereas interventions that lower ROS have a tendency to extend lifespan. However, there are additionally a number of examples in which the other is noticed: rising ROS ranges outcomes in prolonged longevity, and lowering ROS ranges outcomes in shortened lifespan. While these research contradict the predictions of the FRTA, these experiments have been carried out in a really restricted variety of species, all of which have a comparatively quick lifespan.

Overall, the info recommend that the connection between ROS and lifespan is advanced, and that ROS can have each useful or detrimental results on longevity relying on the species and circumstances. Accordingly, the connection between ROS and aging is tough to generalize throughout the tree of life. Vitamin D deficiency is frequent amongst older adults, however its affiliation with bodily perform just isn’t totally understood. The purpose of this examine was to analyze the associations between serum 25-hydroxyvitamin D and incapacity in actions of day by day dwelling (ADL), mobility, and goal bodily functioning amongst Chinese older adults.

AAV-4 Helper Free Packaging System
VPK-404	Cell Biolabs	1 kit	EUR 815

AAV-6 Helper Free Packaging System
VPK-406	Cell Biolabs	1 kit	EUR 815

AAV-DJ Helper Free Packaging System
VPK-400-DJ	Cell Biolabs	1 kit	EUR 815

AAV-DJ/8 Helper Free Packaging System
VPK-400-DJ-8	Cell Biolabs	1 kit	EUR 815

AAV-5 Helper Free Expression System
VPK-410-SER5	Cell Biolabs	1 kit	EUR 1055

AAV-5 Helper Free Promoterless Expression System
VPK-411-SER5	Cell Biolabs	1 kit	EUR 1055

AAV-1 Helper Free Expression System
VPK-410-SER1	Cell Biolabs	1 kit	EUR 1055

AAV-2 Helper Free Expression System
VPK-410-SER2	Cell Biolabs	1 kit	EUR 1055

AAV-3 Helper Free Expression System
VPK-410-SER3	Cell Biolabs	1 kit	EUR 1055

AAV-4 Helper Free Expression System
VPK-410-SER4	Cell Biolabs	1 kit	EUR 1055

AAV-6 Helper Free Expression System
VPK-410-SER6	Cell Biolabs	1 kit	EUR 1055

AAV-DJ Helper Free Expression System
VPK-410-DJ	Cell Biolabs	1 kit	EUR 1055

AAV-5 Helper Free Bicistronic Expression System (Neo)
VPK-416-SER5	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-5 Helper Free Bicistronic Expression System (GFP)
VPK-418-SER5	Cell Biolabs	1 kit	EUR 1055

AAV-5 Helper Free Bicistronic Expression System (Puro)
VPK-415-SER5	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-5 Helper Free Bicistronic Expression System (Hygro)
VPK-417-SER5	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-5 Helper Free Bicistronic Expression System (Blasticidin)
VPK-419-SER5	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-DJ/8 Helper Free Expression System
VPK-410-DJ-8	Cell Biolabs	1 kit	EUR 1055

AAV-1 Helper Free Promoterless Expression System
VPK-411-SER1	Cell Biolabs	1 kit	EUR 1055

AAV-2 Helper Free Promoterless Expression System
VPK-411-SER2	Cell Biolabs	1 kit	EUR 1055

AAV-3 Helper Free Promoterless Expression System
VPK-411-SER3	Cell Biolabs	1 kit	EUR 1055

AAV-4 Helper Free Promoterless Expression System
VPK-411-SER4	Cell Biolabs	1 kit	EUR 1055

AAV-6 Helper Free Promoterless Expression System
VPK-411-SER6	Cell Biolabs	1 kit	EUR 1055

AAV-1 Helper Free Bicistronic Expression System (Neo)
VPK-416-SER1	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-2 Helper Free Bicistronic Expression System (Neo)
VPK-416-SER2	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-3 Helper Free Bicistronic Expression System (Neo)
VPK-416-SER3	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-4 Helper Free Bicistronic Expression System (Neo)
VPK-416-SER4	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-6 Helper Free Bicistronic Expression System (Neo)
VPK-416-SER6	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-1 Helper Free Bicistronic Expression System (GFP)
VPK-418-SER1	Cell Biolabs	1 kit	EUR 1055

AAV-2 Helper Free Bicistronic Expression System (GFP)
VPK-418-SER2	Cell Biolabs	1 kit	EUR 1055

AAV-3 Helper Free Bicistronic Expression System (GFP)
VPK-418-SER3	Cell Biolabs	1 kit	EUR 1055

AAV-4 Helper Free Bicistronic Expression System (GFP)
VPK-418-SER4	Cell Biolabs	1 kit	EUR 1055

AAV-6 Helper Free Bicistronic Expression System (GFP)
VPK-418-SER6	Cell Biolabs	1 kit	EUR 1055

AAV-DJ Helper Free Promoterless Expression System
VPK-411-DJ	Cell Biolabs	1 kit	EUR 1055

AAV-1 Helper Free Bicistronic Expression System (Puro)
VPK-415-SER1	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-2 Helper Free Bicistronic Expression System (Puro)
VPK-415-SER2	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-3 Helper Free Bicistronic Expression System (Puro)
VPK-415-SER3	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-4 Helper Free Bicistronic Expression System (Puro)
VPK-415-SER4	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-6 Helper Free Bicistronic Expression System (Puro)
VPK-415-SER6	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-1 Helper Free Bicistronic Expression System (Hygro)
VPK-417-SER1	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-2 Helper Free Bicistronic Expression System (Hygro)
VPK-417-SER2	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-3 Helper Free Bicistronic Expression System (Hygro)
VPK-417-SER3	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-4 Helper Free Bicistronic Expression System (Hygro)
VPK-417-SER4	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-6 Helper Free Bicistronic Expression System (Hygro)
VPK-417-SER6	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-1 Helper Free Bicistronic Expression System (Blasticidin)
VPK-419-SER1	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-2 Helper Free Bicistronic Expression System (Blasticidin)
VPK-419-SER2	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-3 Helper Free Bicistronic Expression System (Blasticidin)
VPK-419-SER3	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-4 Helper Free Bicistronic Expression System (Blasticidin)
VPK-419-SER4	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-6 Helper Free Bicistronic Expression System (Blasticidin)
VPK-419-SER6	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-DJ/8 Helper Free Promoterless Expression System
VPK-411-DJ-8	Cell Biolabs	1 kit	EUR 1055

AAV-DJ Helper Free Bicistronic Expression System (Neo)
VPK-416-DJ	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2.

AAV-DJ Helper Free Bicistronic Expression System (GFP)
VPK-418-DJ	Cell Biolabs	1 kit	EUR 1055

AAV-DJ Helper Free Bicistronic Expression System (Puro)
VPK-415-DJ	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2.

AAV-DJ Helper Free Bicistronic Expression System (Hygro)
VPK-417-DJ	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2.

2nd Generation Packaging System Mix
LV003	ABM	200 μl	EUR 275

3rd Generation Packaging System Mix
LV053	ABM	200 μl	EUR 325

AAV-DJ Helper Free Bicistronic Expression System (Blasticidin)
VPK-419-DJ	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2.

AAV-DJ/8 Helper Free Bicistronic Expression System (Neo)
VPK-416-DJ-8	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

AAV-DJ/8 Helper Free Bicistronic Expression System (GFP)
VPK-418-DJ-8	Cell Biolabs	1 kit	EUR 1055

AAV-DJ/8 Helper Free Bicistronic Expression System (Puro)
VPK-415-DJ-8	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

AAV-DJ/8 Helper Free Bicistronic Expression System (Hygro)
VPK-417-DJ-8	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

AAV-DJ/8 Helper Free Bicistronic Expression System (Blasticidin)
VPK-419-DJ-8	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

ViraSafe Lentiviral Packaging System, Ecotropic
VPK-205	Cell Biolabs	1 kit	EUR 1069.2
Description: Our ViraSafe Lentiviral Packaging Systems contain three packaging plasmids for co-transfection with your own third generation lentiviral expression construct. If you need an expression vector as well as the packaging plasmids, consider our ViraSafe Lentiviral Expression Complete Systems. Our Ecotropic Packaging System assembles lentiviruses with an ecotropic envelope protein which will readily infect only mouse and rat cells via receptor-mediated binding, providing an additional level of safety. However, ecotropic viruses are not as stable upon freezing and will not survive ultracentrifugation procedure

ViraSafe™ Lentiviral Packaging System, Pantropic
VPK-206	Cell Biolabs	1 kit	EUR 745

scAAV-5 Helper Free Expression System
VPK-430-SER5	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV Packaging Mix (Serotype 5)
AAV1005	ABM	100 µg	EUR 395

scAAV-1 Helper Free Expression System
VPK-430-SER1	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

scAAV-2 Helper Free Expression System
VPK-430-SER2	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

scAAV-3 Helper Free Expression System
VPK-430-SER3	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

scAAV-4 Helper Free Expression System
VPK-430-SER4	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

scAAV-6 Helper Free Expression System
VPK-430-SER6	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

scAAV-DJ Helper Free Expression System
VPK-430-DJ	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2.

AAV Packaging Mix (Serotype 1)
AAV1001	ABM	100 µg	EUR 395

AAV Packaging Mix (Serotype 2)
AAV1002	ABM	100 µg	EUR 395

AAV Packaging Mix (Serotype 3)
AAV1003	ABM	100 µg	EUR 395

AAV Packaging Mix (Serotype 4)
AAV1004	ABM	100 µg	EUR 395

AAV Packaging Mix (Serotype 6)
AAV1006	ABM	100 µg	EUR 395

scAAV-DJ/8 Helper Free Expression System
VPK-430-DJ-8	Cell Biolabs	1 kit	EUR 1486.8
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

pPACK-BALD Envelope-Free Lentivector Packaging Mix
LV550A-1	SBI	10 rxn	EUR 529

Lentivirus packaging plasmids
HT-pack	GenTarget	600ng/ul x 100ul	EUR 556.5
Description: Lentiviral packaging plasmid mixture (60 ug)

pPACK-BALD Envelope-Free Lentivector Packaging Mix (XL)
LV555A-1	SBI	25 rxn	EUR 1167

Fura 2-AM Special Packaging
16439-61	NACALAI TESQUE	1SET	EUR 140

T4 DNA ligase (NEW Packaging sizes)
402-015	GeneOn	6000 WEISS UNITS	EUR 450

pPACKF1 FIV Lentivector Packaging Kit
LV100A-1	SBI	10 transfections	EUR 554

pPACKH1 HIV Lentivector Packaging Kit
LV500A-1	SBI	10 transfections	EUR 529

SuperLenti™ Lentiviral Packaging Mix
VP100	ALSTEM	200ul	EUR 344.4

SuperRetro™ Retroviral Packaging Mix
VP200	ALSTEM	100ul	EUR 344.4

Gryphon Packaging Cell Selection Medium
ABP-TC-PHSM050	Allele Biotech	50 ml	Ask for price
Description: PRODUCT LINE DISCONTINUED. Please contact us.

Lentivirus Packaging Kit (P904=P902+P904P)
P904	101Bio	10 rxn	EUR 579

Retrovirus Packaging Kit (P905=P903+P905P)
P905	101Bio	10 rxn	EUR 579

pPACKH1-XL HIV Lentivector Packaging Kit
LV510A-1	SBI	25 transfections	EUR 1167

pPACKF1 FIV Lentivector Packaging Kit (50 reactions)
LV100A-5	SBI	50 transfections	EUR 2240

Platinum-E Retroviral Packaging Cell Line, Ecotropic
RV-101	Cell Biolabs	1 vial	EUR 770

Platinum-GP Retroviral Packaging Cell Line, Pantropic
RV-103	Cell Biolabs	1 vial	EUR 770

Platinum-A Retroviral Packaging Cell Line, Amphotropic
RV-102	Cell Biolabs	1 vial	EUR 770

Kinesis Membrane Filter empty packaging for samples; 13mm - EACH
FIL1013	Scientific Laboratory Supplies	EACH	EUR 6.75

Kinesis Membrane Filter empty packaging for samples; 25mm - EACH
FIL1015	Scientific Laboratory Supplies	EACH	EUR 6.75

Kinesis Membrane Filter empty packaging for samples; 47mm - EACH
FIL1016	Scientific Laboratory Supplies	EACH	EUR 6.75

SARS-CoV-2 S Protein Pseudotype Lentiviral Packaging Mix
LV700	ABM	200 µl	EUR 375

Lentivirus titer fast detection Strip (special for virus packaging)
E28F06202-10	EnoGene	10 strips	EUR 171.43

pPACK-SPIKE SARS-CoV-2 “S” Pseudotype Lentivector Packaging Mix
CVD19-500A-1	SBI	10 rxn	EUR 677

pPACK-SPIKE SARS-CoV-2 “S” Pseudotype Lentivector Packaging Mix
CVD19-510A-1	SBI	25 rxn	EUR 1349

pPACK-ID: Integrase-defective lentiviral packaging mix (15 reactions)
LV520A-ID	SBI	15 reactions	EUR 633

pPACK-ID: Integrase-defective lentiviral packaging mix (30 reactions)
LV525A-ID	SBI	30 reactions	EUR 1058

Gryphon Ecotropic Packaging Cell Line for Retrovirus (1 x 106 cells, Frozen)
ABP-RVC-10002	Allele Biotech	1 vial	Ask for price
Description: PRODUCT LINE DISCONTINUED. Please contact us.

Gryphon Amphotropic Packaging Cell Line for Retrovirus (1 x 106 cells, Frozen)
ABP-RVC-10001	Allele Biotech	1 vial	Ask for price
Description: PRODUCT LINE DISCONTINUED. Please contact us.

Gryphon Ecotropic Packaging Cell Line for Retrovirus (1 x 106 cells, Culture)
ABP-RVC-10002C	Allele Biotech	1 flask	Ask for price
Description: PRODUCT LINE DISCONTINUED. Please contact us.

Gryphon Amphotropic Packaging Cell Line for Retrovirus (1 x 106 cells, Culture)
ABP-RVC-10001C	Allele Biotech	1 flask	Ask for price
Description: PRODUCT LINE DISCONTINUED. Please contact us.

CMV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV100PA-KIT	SBI	1 Kit	EUR 1037

CMV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV105PA-KIT	SBI	1 Kit	EUR 1037

MSCV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV120PA-KIT	SBI	1 Kit	EUR 1037

MSCV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV125PA-KIT	SBI	1 Kit	EUR 1037

pPACK-SPIKE D614G, SARS-CoV-2 “S” Pseudotype – D614G Mutant – Lentivector Packaging Mix
CVD19-530A-1	SBI	10 rxn	EUR 677

pPACK-SPIKE N501Y SARS-CoV-2 “S” Pseudotype – N501Y Mutant – Lentivector Packaging Mix
CVD19-560A-1	SBI	10 rxn	EUR 677

pPACK-SPIKE B.1.525, SARS-CoV-2 "S" Pseudotype - B.1.525 Variant - Lentivector Packaging Mix
CVD19-620A-1	SBI	10 rxn	EUR 677

pPACK-SPIKE D614G, SARS-CoV-2 “S” Pseudotype – D614G Mutant – Lentivector Packaging Mix (XL)
CVD19-540A-1	SBI	25 rxn	EUR 1349

pPACK-SPIKE N501Y SARS-CoV-2 “S” Pseudotype – N501Y Mutant – Lentivector Packaging Mix (XL)
CVD19-570A-1	SBI	25 rxn	EUR 1349

pPACK-SPIKE B.1.525, SARS-CoV-2 "S" Pseudotype - B.1.525 Variant - Lentivector Packaging Mix (XL)
CVD19-625A-1	SBI	25 rxn	EUR 1349

pPACK-SPIKE B.1.429, SARS-CoV-2 "S" Pseudotype - B.1.429 (CAL.20C) Variant - Lentivector Packaging Mix
CVD19-610A-1	SBI	10 rxn	EUR 677

pPACK-SPIKE B.1.429, SARS-CoV-2 "S" Pseudotype - B.1.429 (CAL.20C) Variant - Lentivector Packaging Mix (XL)
CVD19-615A-1	SBI	25 rxn	EUR 1349

pPACK-SPIKE Beta (B.1.351), SARS-CoV-2 "S" Pseudotype - Beta (B.1.351) Variant - Lentivector Packaging Mix
CVD19-640A-1	SBI	10 rxn	EUR 677

pPACK-SPIKE Beta (B.1.351), SARS-CoV-2 "S" Pseudotype - Beta (B.1.351) Variant - Lentivector Packaging Mix (XL)
CVD19-645A-1	SBI	25 rxn	EUR 1349

pPACK-SPIKE Alpha (B.1.1.7), SARS-CoV-2 "S" Pseudotype - Alpha (B.1.1.7) Variant - Lentivector Packaging Mix
CVD19-590A-1	SBI	10 rxn	EUR 677

pPACK-SPIKE Gamma (P.1), SARS-CoV-2 "S" Pseudotype - Gamma (P.1) Variant - Lentivector Packaging Mix
CVD19-630A-1	SBI	10 rxn	EUR 677

pPACK-SPIKE Delta (B.1.617.2), SARS-CoV-2 "S" Pseudotype - Delta (B.1.617.2) Variant - Lentivector Packaging Mix
CVD19-650A-1	SBI	10 rxn	EUR 677

Cas9 Nickase: CMV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV205PA-KIT	SBI	1 Kit	EUR 1037

pPACK-SPIKE Alpha (B.1.1.7), SARS-CoV-2 "S" Pseudotype - Alpha (B.1.1.7) Variant - Lentivector Packaging Mix (XL)
CVD19-595A-1	SBI	25 rxn	EUR 1349

pPACK-SPIKE Gamma (P.1), SARS-CoV-2 "S" Pseudotype - Gamma (P.1) Variant - Lentivector Packaging Mix (XL)
CVD19-635A-1	SBI	25 rxn	EUR 1349

pPACK-SPIKE Delta (B.1.617.2), SARS-CoV-2 "S" Pseudotype - Delta (B.1.617.2) Variant - Lentivector Packaging Mix (XL)
CVD19-655A-1	SBI	25 rxn	EUR 1349

Cas9 Nickase: CMV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV200PA-KIT	SBI	1 Kit	EUR 1037

Cas9 Nickase: MSCV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV220PA-KIT	SBI	1 Kit	EUR 1037

Cas9 Nickase: MSCV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV225PA-KIT	SBI	1 Kit	EUR 1037

pPACK-SPIKE Omicron (B.1.1.529), SARS-CoV-2 "S" Pseudotype - Omicron (B.1.1.529) Variant - Lentivector Packaging Mix
CVD19-660A-1	SBI	10 rxn	EUR 698

pPACK-SPIKE Omicron (B.1.1.529), SARS-CoV-2 "S" Pseudotype - Omicron (B.1.1.529) Variant - Lentivector Packaging Mix
CVD19-665A-1	SBI	25 rxn	EUR 1380

Myc-DDK-tagged ORF clone of viral ORF for DNA packaging protein UL33 [Human herpesvirus 5], codon optimized for human cell expression, YP_081510
VC101241	Origene Technologies GmbH	10 µg	Ask for price

Myc-DDK-tagged ORF clone of viral ORF for DNA packaging protein UL32 [Human herpesvirus 5], codon optimized for human cell expression, YP_081511
VC101242	Origene Technologies GmbH	10 µg	Ask for price

Myc-DDK-tagged ORF clone of viral ORF for DNA packaging terminase subunit 2 [Human herpesvirus 5], codon optimized for human cell expression, YP_
VC101246	Origene Technologies GmbH	10 µg	Ask for price

Myc-DDK-tagged ORF clone of viral ORF for DNA packaging terminase subunit 1 [Human herpesvirus 5], codon optimized for human cell expression, YP_
VC101269	Origene Technologies GmbH	10 µg	Ask for price

pPACK-SPIKE B.1.351 RBD Mutations, SARS-CoV-2 "S" Pseudotype - B.1.351 (S. African) Variant - RBD Mutations - Lentivector Packaging Mix
CVD19-580A-1	SBI	10 rxn	EUR 677

pPACK-SPIKE B.1.351 RBD Mutations, SARS-CoV-2 "S" Pseudotype - B.1.351 (S. African) Variant - RBD Mutations - Lentivector Packaging Mix (XL)
CVD19-585A-1	SBI	25 rxn	EUR 1349

We used cross-sectional information of 2225 older adults (≥65 years) who participated in the 2011/2012 major survey of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) and the 2012 biomarker sub-study. Serum ranges of 25-hydroxyvitamin D have been measured by enzyme immunoassay. Outcomes included ADL incapacity, mobility incapacity, and incapacity in three goal bodily examinations (standing-up from a chair, picking-up a e-book from the ground, and turning-around 360°).