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FOXO3A genotype is strongly associated with human longevity.

FOXO3A genotype is strongly associated with human longevity.

Human longevity is a fancy phenotype with a major familial part, but little is recognized about its genetic antecedents. Increasing proof from animal fashions means that the insulin/IGF-1 signaling (IIS) pathway is an necessary, evolutionarily conserved organic pathway that influences growing old and longevity. However, so far human knowledge have been scarce. Studies have been hampered by small pattern sizes, lack of exact phenotyping, and inhabitants stratification, amongst different challenges.

Therefore, to extra exactly assess potential genetic contributions to human longevity from genes linked to IIS signaling, we selected a big, homogeneous, long-lived inhabitants of males well-characterized for growing old phenotypes, and we carried out a nested-case management research of 5 candidate longevity genes. Genetic variation inside the FOXO3A gene was strongly associated with human longevity. The OR for homozygous minor vs. homozygous main alleles between the instances and controls was 2.75 (P = 0.00009; adjusted P = 0.00135).

Long-lived males additionally introduced a number of extra phenotypes linked to wholesome growing old, together with decrease prevalence of most cancers and heart problems, higher self-reported well being, and excessive bodily and cognitive perform, regardless of considerably older ages than controls. Several of those growing old phenotypes had been associated with FOXO3A genotype. Long-lived males additionally exhibited a number of organic markers indicative of larger insulin sensitivity and this was associated with homozygosity for the FOXO3A GG genotype. Further exploration of the FOXO3A gene, human longevity and different growing old phenotypes is warranted in different populations.

Oxidative stress influences cell survival and homeostasis, however the mechanisms underlying the organic results of oxidative stress stay to be elucidated. Here, we reveal that the protein kinase MST1 mediates oxidative-stress-induced cell dying in main mammalian neurons by straight activating the FOXO transcription elements. MST1 phosphorylates FOXO proteins at a conserved website inside the forkhead area that disrupts their interplay with 14-3-Three proteins, promotes FOXO nuclear translocation, and thereby induces cell dying in neurons.

We additionally prolong the MST-FOXO signaling hyperlink to nematodes. Knockdown of the C. elegans MST1 ortholog CST-1 shortens life span and accelerates tissue growing old, whereas overexpression of cst-1 promotes life span and delays growing old. The cst-1-induced life-span extension happens in a daf-16-dependent method. The identification of the FOXO transcription elements as main and evolutionarily conserved targets of MST1 means that MST kinases play necessary roles in various organic processes together with mobile responses to oxidative stress and longevity.

Astrocytes as Perspective Targets of Exercise- and Caloric Restriction-Mimetics

 

Enhanced psychological and bodily exercise can have constructive results on the perform of growing old mind, each within the experimental animals and human sufferers, though mobile mechanisms underlying these results are presently unclear. There is a rising proof that pre-clinical stage of many neurodegenerative illnesses includes modifications in interactions between astrocytes and neurons. Conversely, astrocytes are strategically positioned to mediate the constructive affect of bodily exercise and food regimen on neuronal perform.

Thus, improvement of therapeutic brokers which might enhance the astroglia-neuron communications in ageing mind is of essential significance. Recent advances in research of mobile mechanisms of mind longevity counsel that astrocyte-neuron communications have a significant function within the useful results of caloric restriction, bodily train and their pharmacological mimetics on synaptic homeostasis and cognitive perform.

In explicit, our current knowledge point out that noradrenaline uptake inhibitor atomoxetine can improve astrocytic Ca2+-signaling and astroglia-driven modulation of synaptic plasticity. Similar results had been exhibited by caloric restriction-mimetics metformin and resveratrol. The emerged knowledge additionally counsel that astrocytes may very well be concerned within the modulatory motion of caloric restriction and its mimetics on neuronal autophagy. Still, the effectivity of astrocyte-targeting compounds in stopping age-related cognitive decline is but to be absolutely explored, specifically within the animal fashions of neurodegenerative illnesses and autophagy impairment.

FOXO3A genotype is strongly associated with human longevity.

Accelerated Aging and Age-Related Diseases (CVD and Neurological) Due to Air Pollution and Traffic Noise Exposure

 

The World Health Organization estimates that solely roughly 25% of range in longevity is defined by genetic elements, whereas the opposite 75% is largely decided by interactions with the bodily and social environments. Indeed, growing old is a multifactorial course of that is influenced by a spread of environmental, sociodemographic, and biopsychosocial elements, all of which could act in live performance to find out the method of growing old.

The international common life expectancy elevated basically over the previous century, towards an growing old inhabitants, correlating with the event and onset of age-related illnesses, primarily from cardiovascular and neurological nature. Therefore, the identification of determinants of wholesome and unhealthy growing old is a significant aim to decrease the burden and socioeconomic prices of age-related illnesses.

Pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E07A0057-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E07A0057-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E07A0057-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E08A0057-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E08A0057-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E08A0057-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E06A0057-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E06A0057-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E06A0057-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A8819 96T
EUR 700
Description: ELISA

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E01A0057-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E01A0057-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E03A0057-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E03A0057-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E03A0057-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA Kit
NSL1442Hu 96 wells
EUR 468

Goat LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A43740 96T
EUR 700
Description: ELISA

Rabbit LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E04A0057-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E04A0057-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E04A0057-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E09A0057-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E09A0057-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E09A0057-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Bovine LAG1 longevity assurance homolog 3(LASS3) ELISA Kit
NSL1118Bo 96 T
EUR 528

Canine LAG1 longevity assurance homolog 3(LASS3) ELISA Kit
NSL1145Ca 1240 wells
EUR 528

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A0054 96T
EUR 700
Description: ELISA

Sheep LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A96033 96T
EUR 700
Description: ELISA

Mouse LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A17561 96T
EUR 700
Description: ELISA

Canine LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A61175 96T
EUR 700
Description: ELISA

Rabbit LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A26308 96T
EUR 700
Description: ELISA

Bovine LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A78604 96T
EUR 700
Description: ELISA

Monkey LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A69887 96T
EUR 700
Description: ELISA

Chicken LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A87330 96T
EUR 700
Description: ELISA

Human LAG1 longevity assurance homolog 6 (LASS6) ELISA Kit
EK10150 96Т
EUR 799

Human LAG1 longevity assurance homolog 2 (LASS2) ELISA Kit
EK10151 96Т
EUR 799

Human LAG1 longevity assurance homolog 6 (LASS6) ELISA Kit
AE35956HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 6 (LASS6) ELISA Kit
AE35956HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 4 (LASS4) ELISA Kit
AE35958HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 4 (LASS4) ELISA Kit
AE35958HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 2 (LASS2) ELISA Kit
AE35962HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 2 (LASS2) ELISA Kit
AE35962HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 1 (LASS1) ELISA Kit
AE35965HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 1 (LASS1) ELISA Kit
AE35965HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

Mouse LAG1 longevity assurance homolog 1 (LASS1) ELISA Kit
RK12828 96T
EUR 280

Human LAG1 longevity assurance homolog 1 (LASS1) ELISA Kit
RK10479 96T
EUR 280

Guinea pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E05A0057-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E05A0057-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E05A0057-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

LAG1 Longevity Assurance Homolog 3 (LASS3) Antibody
abx430427-200ul 200 ul
EUR 460.8

Guinea Pig LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A35022 96T
EUR 700
Description: ELISA

ELISA kit for Human LAG1 longevity assurance homolog 6 (LASS6)
KTE61852-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 6 (LASS6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human LAG1 longevity assurance homolog 6 (LASS6)
KTE61852-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 6 (LASS6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human LAG1 longevity assurance homolog 6 (LASS6)
KTE61852-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 6 (LASS6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human LAG1 longevity assurance homolog 2 (LASS2)
KTE61853-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 2 (LASS2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human LAG1 longevity assurance homolog 2 (LASS2)
KTE61853-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 2 (LASS2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human LAG1 longevity assurance homolog 2 (LASS2)
KTE61853-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 2 (LASS2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

LAG1 Longevity Assurance Homolog 4 (LASS4) Antibody
20-abx008040
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  • 100 ul
  • 200 ul
  • 30 ul

LAG1 Longevity Assurance Homolog 4 (LASS4) Antibody
20-abx013801
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  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

LAG1 Longevity Assurance Homolog 2 (LASS2) Antibody
abx019124-100ug 100 ug
EUR 410.4

LAG1 Longevity Assurance Homolog 4 (LASS4) Antibody
abx013801-100l 100 µl
EUR 43.75

Human Longevity Assurance Homolog 2 ELISA Kit
IHULASS2KT each
EUR 799
Description: Human Longevity Assurance Homolog 2 ELISA Kit

Human LASS2(Longevity Assurance Homolog 2) ELISA Kit
ELK7214-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human LASS2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human LASS2. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human LASS2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human LASS2 in the samples is then determined by comparing the OD of the samples to the standard curve.

Human LASS2(Longevity Assurance Homolog 2) ELISA Kit
ELK7214-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human LASS2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human LASS2. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human LASS2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human LASS2 in the samples is then determined by comparing the OD of the samples to the standard curve.

Human LASS6(Longevity Assurance Homolog 6) ELISA Kit
ELK7613-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human LASS6. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human LASS6. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human LASS6, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human LASS6 in the samples is then determined by comparing the OD of the samples to the standard curve.

Human LASS6(Longevity Assurance Homolog 6) ELISA Kit
ELK7613-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human LASS6. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human LASS6. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human LASS6, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human LASS6 in the samples is then determined by comparing the OD of the samples to the standard curve.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
DLR-LASS2-Hu 96T
EUR 505
Description: tissue homogenates, cell lysates or other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
DLR-LASS2-Hu-48T 48T
EUR 664.8
Description: A sandwich quantitative ELISA assay kit for detection of Human Longevity Assurance Homolog 2 (LASS2) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
DLR-LASS2-Hu-96T 96T
EUR 870
Description: A sandwich quantitative ELISA assay kit for detection of Human Longevity Assurance Homolog 2 (LASS2) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
EKU09363-48T 48T
EUR 610.82

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
EKU09363-5x96T 5x96T
EUR 4144.85

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
EKU09363-96T 96T
EUR 872.6

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
EKN50474-48T 48T
EUR 380.31

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
EKN50474-5x96T 5x96T
EUR 2580.68

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
EKN50474-96T 96T
EUR 543.3

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKU05672-48T 48T
EUR 610.82

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKU05672-5x96T 5x96T
EUR 4144.85

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKU05672-96T 96T
EUR 872.6

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKN46783-48T 48T
EUR 416.29

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKN46783-5x96T 5x96T
EUR 2824.83

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKN46783-96T 96T
EUR 594.7

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
DL-LASS2-Hu 96T
EUR 481
Description: tissue homogenates, cell lysates or other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EK15188 96Т
EUR 768

Human Longevity Assurance Homolog 2 (CERS2) ELISA Kit
abx388232-96tests 96 tests
EUR 1093.2

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
20-abx258682
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
20-abx152171
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RD-LASS2-Hu-48T 48T
EUR 493.5
Description: tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RD-LASS2-Hu-48Tests 48 Tests
EUR 675.6

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RD-LASS2-Hu-96T 96T
EUR 705
Description: tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RD-LASS2-Hu-96Tests 96 Tests
EUR 939.6

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
SER156Hu-10x96wellstestplate 10x96-wells test plate
EUR 6227.58
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 6 (LASS6) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
SER156Hu-1x48wellstestplate 1x48-wells test plate
EUR 618.04
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 6 (LASS6) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
SER156Hu-1x96wellstestplate 1x96-wells test plate
EUR 831.48
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 6 (LASS6) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
SER156Hu-5x96wellstestplate 5x96-wells test plate
EUR 3381.66
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 6 (LASS6) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
4-SER156Hu
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  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Longevity Assurance Homolog 6 (LASS6) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
SEP312Hu-10x96wellstestplate 10x96-wells test plate
EUR 6227.58
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
SEP312Hu-1x48wellstestplate 1x48-wells test plate
EUR 618.04
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
SEP312Hu-1x96wellstestplate 1x96-wells test plate
EUR 831.48
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
SEP312Hu-5x96wellstestplate 5x96-wells test plate
EUR 3381.66
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
4-SEP312Hu
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  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Longevity Assurance Homolog 2 (LASS2) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RDR-LASS2-Hu-48T 48T
EUR 518.18
Description: tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RDR-LASS2-Hu-48Tests 48 Tests
EUR 706.8

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RDR-LASS2-Hu-96T 96T
EUR 740.25
Description: tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RDR-LASS2-Hu-96Tests 96 Tests
EUR 984

ELISA kit for Human LASS2 (Longevity Assurance Homolog 2)
ELK7214 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Longevity Assurance Homolog 2 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Human LASS6 (Longevity Assurance Homolog 6)
ELK7613 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Longevity Assurance Homolog 6 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

LASS2 (untagged)-Human LAG1 longevity assurance homolog 2 (S. cerevisiae) (LASS2), transcript variant 3
SC110410 10 µg Ask for price

Longevity Assurance Homolog 2 (LASS2) Antibody
20-abx173382
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  • 1 mg
  • 200 ug

Longevity Assurance Homolog 2 (LASS2) Antibody
20-abx177383
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  • 1 mg
  • 200 ug

Longevity Assurance Homolog 2 (LASS2) Antibody
abx234705-100ug 100 ug
EUR 661.2

Longevity Assurance Homolog 6 (LASS6) Antibody
abx029719-400ul 400 ul
EUR 627.6

Longevity Assurance Homolog 6 (LASS6) Antibody
abx029719-80l 80 µl
EUR 343.2

Human Longevity Assurance Homolog 2 (LASS2) CLIA Kit
20-abx496121
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Longevity Assurance Homolog 6 (LASS6) CLIA Kit
20-abx496220
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

LASS3 (untagged)-Human LAG1 longevity assurance homolog 3 (S. cerevisiae) (cDNA clone MGC:26920 IMAGE:4837657), complete cds
SC122492 10 µg Ask for price

Human Longevity Assurance Homolog 2 (LASS2) Protein
20-abx654210
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Longevity Assurance Homolog 2 (LASS2) Magnetic Luminex Assay Kit
LKU602152-96T 96T
EUR 1062.6

Longevity Assurance Homolog 6 (LASS6) Magnetic Luminex Assay Kit
LKU602157-96T 96T
EUR 1062.6

Longevity Assurance Gene 1 Protein Homolog 1 (LASS1) Antibody
abx432242-200ul 200 ul
EUR 460.8

Longevity Assurance Gene 1 Protein Homolog 1 (LASS1) Antibody
abx432242-100g 100 µg
EUR 387.5

Cers2 (GFP-tagged) - Mouse longevity assurance homolog 2 (S. cerevisiae) (Lass2)
MG205931 10 µg Ask for price

Cers6 (GFP-tagged) - Mouse longevity assurance homolog 6 (S. cerevisiae) (Lass6)
MG205998 10 µg Ask for price

Cers4 (GFP-tagged) - Mouse longevity assurance homolog 4 (S. cerevisiae) (Lass4)
MG206130 10 µg Ask for price

Cers5 (GFP-tagged) - Mouse longevity assurance homolog 5 (S. cerevisiae) (Lass5)
MG206528 10 µg Ask for price

Lass5 (GFP-tagged) - Mouse longevity assurance homolog 5 (S. cerevisiae) (cDNA clone MGC:57962 IMAGE:6419704)
MG206047 10 µg Ask for price

Lass5 (Myc-DDK-tagged) - Mouse longevity assurance homolog 5 (S. cerevisiae) (cDNA clone MGC:57962 IMAGE:6419704)
MR206047 10 µg Ask for price

Lenti ORF clone of Lass5 (mGFP-tagged) - Mouse longevity assurance homolog 5 (S. cerevisiae) (cDNA clone MGC:57962 IMAGE:6419704)
MR206047L4 10 µg Ask for price

Lenti ORF clone of Lass5 (Myc-DDK-tagged) - Mouse longevity assurance homolog 5 (S. cerevisiae) (cDNA clone MGC:57962 IMAGE:6419704)
MR206047L3 10 µg Ask for price

Lenti ORF particles, Lass5 (GFP-tagged) - Mouse longevity assurance homolog 5 (S. cerevisiae) (cDNA clone MGC:57962 IMAGE:6419704), 200ul, >10^7
MR206047L4V 200 µl Ask for price

Lenti ORF particles, Lass5 (Myc-DDK-tagged) - Mouse longevity assurance homolog 5 (S. cerevisiae) (cDNA clone MGC:57962 IMAGE:6419704), 200ul, >1
MR206047L3V 200 µl Ask for price

Porcine B7 Homolog 3 ELISA kit
E01A54073 96T
EUR 700
Description: ELISA

Porcine Slit Homolog 3 ELISA kit
E01A60407 96T
EUR 700
Description: ELISA

Porcine Chromobox Homolog 3 ELISA kit
E01A54681 96T
EUR 700
Description: ELISA

Porcine Snail Homolog ELISA kit
E01A60353 96T
EUR 700
Description: ELISA

Porcine Slit Homolog 2 ELISA kit
E01A60109 96T
EUR 700
Description: ELISA

Porcine Frizzied homolog 8 ELISA kit
E01A56882 96T
EUR 700
Description: ELISA

Porcine BET1 homolog(BET1) ELISA kit
E01A54236 96T
EUR 700
Description: ELISA

Porcine Protein δ Homolog 1 ELISA kit
E01A56578 96T
EUR 700
Description: ELISA

Porcine Slit2(Slit Homolog 2) ELISA Kit
EP0151 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Pig;Sensitivity: 0.188 ng/ml

Slit2 ELISA Kit| Porcine Slit Homolog 2 ELISA Kit
EF016691 96 Tests
EUR 826.8

Porcine Achaete scute homolog 3(ASCL3) ELISA kit
E01A52821 96T
EUR 700
Description: ELISA

Porcine Crumbs protein homolog 3(CRB3) ELISA kit
E01A55903 96T
EUR 700
Description: ELISA

Porcine BUD13 homolog(BUD13) ELISA kit
E01A54306 96T
EUR 700
Description: ELISA

Porcine Yorkie homolog(YAP1) ELISA kit
E01A61068 96T
EUR 700
Description: ELISA

Porcine Protein canopy homolog 3(CNPY3) ELISA kit
E01A59549 96T
EUR 700
Description: ELISA

Porcine Protein canopy homolog 3, CNPY3 ELISA KIT
ELI-10589p 96 Tests
EUR 1113.6

Porcine Achaete scute homolog 1 ELISA kit
E01A52463 96T
EUR 700
Description: ELISA

Porcine Hedgehog Homolog, Sonic ELISA kit
E01A60103 96T
EUR 700
Description: ELISA

Porcine Smoothened homolog(SMO) ELISA kit
E01A60297 96T
EUR 700
Description: ELISA

Porcine Protein pellino homolog 1 ELISA kit
E01A59344 96T
EUR 700
Description: ELISA

Porcine Mothers against decapentaplegic homolog 3 ELISA kit
E01A60111 96T
EUR 700
Description: ELISA

Porcine Hedgehog Homolog, Indian ELISA kit
E01A57627 96T
EUR 700
Description: ELISA

Porcine Protein dachsous homolog 2 ELISA kit
E01A56597 96T
EUR 700
Description: ELISA

Porcine Slit Homolog 2(Slit2) ELISA Kit
NSL0150Po 96T
EUR 528

Porcine Anterior Gradient Homolog 2 ELISA kit
E01A52571 96T
EUR 700
Description: ELISA

Porcine Adrenocortical Dysplasia Homolog ELISA kit
E01A52654 96T
EUR 700
Description: ELISA

Porcine Crumbs homolog 1(CRB1) ELISA kit
E01A55901 96T
EUR 700
Description: ELISA

Porcine Crumbs homolog 2(CRB2) ELISA kit
E01A55902 96T
EUR 700
Description: ELISA

Porcine Protein unc-13 homolog D ELISA kit
E01A58482 96T
EUR 700
Description: ELISA

Porcine Enhancer of zeste homolog 2 ELISA kit
E01A56642 96T
EUR 700
Description: ELISA

Porcine Teashirt homolog 2, TSHZ2 ELISA KIT
ELI-40365p 96 Tests
EUR 1113.6

Porcine Protein Muted homolog(MUTED) ELISA kit
E01A59564 96T
EUR 700
Description: ELISA

Porcine Protein Muted homolog, MUTED ELISA KIT
ELI-36857p 96 Tests
EUR 1113.6

Assurance Grade Water Blank for ICP 500mL
PLBLK-HCL 500ML
EUR 58.29

Porcine seminal plasma protein homolog 1 ELISA kit
E01A54290 96T
EUR 700
Description: ELISA

The function of environmental elements (comparable to air air pollution and noise publicity) as essential determinants of the growing old course of are being more and more acknowledged. Here, we critically assessment current findings in regards to the pathomechanisms underlying the growing old course of and their correlates in cardiovascular and neurological illness, centered on oxidative stress and irritation, in addition to the affect of outstanding environmental pollution, particularly air air pollution and visitors noise publicity.