CSB-DM007B1

Instrumental Activities of Daily Living (IADL) is an indicator of whether a community-dwelling elderly can live independently. IADL decline was reported to be associated with aging and depression.

The present study aimed to investigate whether the association between IADL decline and depressive symptoms differs with aging, using two age groups of community-dwelling Japanese elderly in their 70s and 80s.We conducted longitudinal analysis among participants in their 70s and 80s at the baseline from Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians (SONIC) study. IADL was assessed by The Tokyo Metropolitan Institute of Gerontology (TMIG) index of competence.

CSB Rabbit Polyclonal Antibody

ES5167-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against CSB from Human. This antibody is tested and validated for IHC, WB, ELISA

CSB Rabbit Polyclonal Antibody

ES5167-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against CSB from Human. This antibody is tested and validated for IHC, WB, ELISA

Cronobacter Selective Broth (CSB)

M1786I-100G 1 unit
EUR 12.35
Description: Cronobacter Selective Broth (CSB)

Cronobacter Selective Broth (CSB)

M1786I-500G 1 unit
EUR 32.87
Description: Cronobacter Selective Broth (CSB)

CSB/COD Thermoreactor RD126 - EACH

WAT2040 EACH
EUR 1405.35

CSB; Cytokine Stabilization Buffer ELISA

CT373 5 ml
EUR 114

CSB Antibody / Cockayne Syndrome B / ERCC6

R32528 100 ug
EUR 356.15
Description: DNA excision repair protein ERCC-6 (also CS-B protein) is a protein that in humans is encoded by the ERCC6 gene. This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Alternative splicing occurs between a splice site from exon 5 of this gene to the 3' splice site upstream of the open reading frame (ORF) of the adjacent gene, piggyback-derived-3, which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene.

D630003M21Rik (Myc-DDK-tagged) - Mouse RIKEN cDNA D630003M21 gene (D630003M21Rik), transcript variant 2

MR214796 10 µg Ask for price

D630003M21Rik (Myc-DDK-tagged) - Mouse RIKEN cDNA D630003M21 gene (D630003M21Rik), transcript variant 1

MR214801 10 µg Ask for price

D630003M21Rik (GFP-tagged) - Mouse RIKEN cDNA D630003M21 gene (D630003M21Rik) transcript variant 2, (10ug)

MG214796 10 µg Ask for price

D630003M21Rik (GFP-tagged) - Mouse RIKEN cDNA D630003M21 gene (D630003M21Rik) transcript variant 1, (10ug)

MG214801 10 µg Ask for price

D630003M21Rik (untagged) - Mouse RIKEN cDNA D630003M21 gene (D630003M21Rik), transcript variant 2, (10ug)

MC223600 10 µg Ask for price

D630003M21Rik (untagged) - Mouse RIKEN cDNA D630003M21 gene (D630003M21Rik), transcript variant 1, (10ug)

MC223899 10 µg Ask for price

Lenti ORF clone of D630003M21Rik (Myc-DDK-tagged) - Mouse RIKEN cDNA D630003M21 gene (D630003M21Rik), transcript variant 2

MR214796L3 10 µg Ask for price

Lenti ORF clone of D630003M21Rik (mGFP-tagged) - Mouse RIKEN cDNA D630003M21 gene (D630003M21Rik), transcript variant 2

MR214796L4 10 µg Ask for price

Lenti ORF clone of D630003M21Rik (Myc-DDK-tagged) - Mouse RIKEN cDNA D630003M21 gene (D630003M21Rik), transcript variant 1

MR214801L3 10 µg Ask for price

Lenti ORF clone of D630003M21Rik (mGFP-tagged) - Mouse RIKEN cDNA D630003M21 gene (D630003M21Rik), transcript variant 1

MR214801L4 10 µg Ask for price

Lenti ORF particles, D630003M21Rik (GFP-tagged) - Mouse RIKEN cDNA D630003M21 gene (D630003M21Rik), transcript variant 2, 200ul, >10^7 TU/mL

MR214796L4V 200 µl Ask for price

Lenti ORF particles, D630003M21Rik (GFP-tagged) - Mouse RIKEN cDNA D630003M21 gene (D630003M21Rik), transcript variant 1, 200ul, >10^7 TU/mL

MR214801L4V 200 µl Ask for price

Lenti ORF particles, D630003M21Rik (Myc-DDK-tagged) - Mouse RIKEN cDNA D630003M21 gene (D630003M21Rik), transcript variant 2, 200ul, >10^7 TU/mL

MR214796L3V 200 µl Ask for price

Lenti ORF particles, D630003M21Rik (Myc-DDK-tagged) - Mouse RIKEN cDNA D630003M21 gene (D630003M21Rik), transcript variant 1, 200ul, >10^7 TU/mL

MR214801L3V 200 µl Ask for price

D230010M03Rik (GFP-tagged) - Mouse RIKEN cDNA D230010M03 gene (cDNA clone MGC:106582 IMAGE:5716740)

MG205273 10 µg Ask for price

Dialysis Tubing No. 4 (DM003)

LA393-1MT 1 unit
EUR 7.6
Description: Dialysis Tubing No. 4 (DM003)

DM21

T39743-10mg 10mg Ask for price
Description: DM21

DM21

T39743-1g 1g Ask for price
Description: DM21

DM21

T39743-1mg 1mg Ask for price
Description: DM21

DM21

T39743-50mg 50mg Ask for price
Description: DM21

DM21

T39743-5mg 5mg Ask for price
Description: DM21

DM-01

T62403-10mg 10mg Ask for price
Description: DM-01

DM-01

T62403-1g 1g Ask for price
Description: DM-01

DM-01

T62403-1mg 1mg Ask for price
Description: DM-01

DM-01

T62403-50mg 50mg Ask for price
Description: DM-01

DM-01

T62403-5mg 5mg Ask for price
Description: DM-01

D630003M21Rik ORF Vector (Mouse) (pORF)

ORF042552 1.0 ug DNA
EUR 607.2

D630003M21Rik ORF Vector (Mouse) (pORF)

ORF042553 1.0 ug DNA
EUR 607.2

D630003M21Rik 3'UTR GFP Stable Cell Line

TU154800 1.0 ml Ask for price

anti-CSB

YF-PA23663 50 ul
EUR 400.8
Description: Mouse polyclonal to CSB

D630003M21Rik Protein Vector (Mouse) (pPM-C-HA)

PV170208 500 ng
EUR 1278

D630003M21Rik Protein Vector (Mouse) (pPM-C-HA)

PV170212 500 ng
EUR 1278

D630003M21Rik Protein Vector (Mouse) (pPB-C-His)

PV170206 500 ng
EUR 1278

D630003M21Rik Protein Vector (Mouse) (pPB-N-His)

PV170207 500 ng
EUR 1278

D630003M21Rik Protein Vector (Mouse) (pPM-C-His)

PV170209 500 ng
EUR 1278

D630003M21Rik Protein Vector (Mouse) (pPB-C-His)

PV170210 500 ng
EUR 1278

D630003M21Rik Protein Vector (Mouse) (pPB-N-His)

PV170211 500 ng
EUR 1278

D630003M21Rik Protein Vector (Mouse) (pPM-C-His)

PV170213 500 ng
EUR 1278

D630003M21Rik 3'UTR Luciferase Stable Cell Line

TU104800 1.0 ml Ask for price

D630003M21Rik sgRNA CRISPR Lentivector set (Mouse)

K3278701 3 x 1.0 ug
EUR 406.8

D630003M21Rik sgRNA CRISPR Lentivector (Mouse) (Target 1)

K3278702 1.0 ug DNA
EUR 184.8

D630003M21Rik sgRNA CRISPR Lentivector (Mouse) (Target 2)

K3278703 1.0 ug DNA
EUR 184.8

D630003M21Rik sgRNA CRISPR Lentivector (Mouse) (Target 3)

K3278704 1.0 ug DNA
EUR 184.8

D830039M14Rik (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each

SR404713 2 nmol Ask for price

D730002M21Rik (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each

SR400796 2 nmol Ask for price

D930028M14Rik (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each

SR401044 2 nmol Ask for price

D630003M21Rik (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each

SR422084 2 nmol Ask for price

D630003M21Rik sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K3278705 3 x 1.0 ug
EUR 451.2

D630003M21Rik sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K3278706 1.0 ug DNA
EUR 200.4

D630003M21Rik sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K3278707 1.0 ug DNA
EUR 200.4

D630003M21Rik sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K3278708 1.0 ug DNA
EUR 200.4

D630003M21Rik - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector

TL506824 5 µg/vial Ask for price

Anti-CS1 antibody(DM10), Rabbit mAb

29622 100ug
EUR 1009

Anti-CS1 antibody(DM11),Rabbit mAb

29623 100ug
EUR 1009

Anti-CS1 antibody (DM10) , Rabbit mAb

E33D100010 10 μl
EUR 225
Description: Available in various conjugation types.

Anti-CS1 antibody (DM11) ,Rabbit mAb

E33D100011 10 μl
EUR 225
Description: Available in various conjugation types.

LPS from Escherichia coli K12, D31m4 (Re)

302 5mg
EUR 200

Anti-CD22 antibody(DM12),Rabbit mAb

29624 100ug
EUR 1009

Anti-CD22 antibody(DM13),Rabbit mAb

29625 100ug
EUR 1009

Anti-CD22 antibody(DM14),Rabbit mAb

29626 100ug
EUR 1009

Anti-BCMA antibody(DM16), Rabbit mAb

29631 100ug
EUR 1009

Anti-CD38 antibody(DM28), Rabbit mAb

29636 100ug
EUR 1009

Anti-CD38 antibody(DM29), Rabbit mAb

29637 100ug
EUR 1009

Anti-CD38 antibody(DM30), Rabbit mAb

29638 100ug
EUR 1009

Anti-CD22 antibody (DM12) , Rabbit mAb

E33D100012 10 μl
EUR 225
Description: Available in various conjugation types.

Anti-CD22 antibody (DM13) , Rabbit mAb

E33D100013 10 μl
EUR 225
Description: Available in various conjugation types.

Anti-CD22 antibody (DM14) , Rabbit mAb

E33D100014 10 μl
EUR 225
Description: Available in various conjugation types.

Diphosphoryl Lipid A (E. coli K12 D31m4)

AV-7040-1 1 mg
EUR 634.8

Diphosphoryl Lipid A (E. coli K12 D31m4)

AV-7040-5 5 mg
EUR 2535.6

D630003M21Rik - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector

TR506824 5 µg/vial Ask for price

Anti-CD123 antibody(DM31), Rabbit mAb

29640 100ug
EUR 1009

Anti-CD123 antibody(DM33), Rabbit mAb

29641 100ug
EUR 1009

Anti-CD123 antibody(DM34), Rabbit mAb

29642 100ug
EUR 1009

Anti-BCMA bispecific antibody(DM16)

29633 100ug
EUR 1009

Anti-SARS-CoV-2 RBD antibody(DM35), Rabbit mAb

29639 100ug
EUR 829

Anti-CSB antibody

STJ92493 200 µl
EUR 236.4
Description: Rabbit polyclonal to CSB.

Anti-SARS-CoV-2 Spike antibody(DM39), Rabbit mAb

29646 100ug
EUR 829

Anti-SARS-CoV-2 Spike antibody(DM40), Rabbit mAb

29647 100ug
EUR 829

Anti-SARS-CoV-2 Spike antibody(DM41), Rabbit mAb

29648 100ug
EUR 829

D630003M21Rik - Mouse shRNA lentiviral particles (4 unique 29mer target-specific shRNA, 1 scramble control), 0.5 ml each, >10^7 TU/ml.

TL506824V 500 ul each Ask for price

D230010M03Rik - Mouse shRNA lentiviral particles (4 unique 29mer target-specific shRNA, 1 scramble control), 0.5 ml each, >10^7 TU/ml.

TL507344V 500 ul each Ask for price

Anti-SIRPα(DM8) antibody, Rabbit mAb

29620 100ug
EUR 1009

Anti-SARS-CoV-2 Nucleocapsid antibody(DM36), Rabbit mAb

29643 100ug
EUR 829

Anti-SARS-CoV-2 Nucleocapsid antibody(DM37), Rabbit mAb

29644 100ug
EUR 829

Anti-SARS-CoV-2 Nucleocapsid antibody(DM38), Rabbit mAb

29645 100ug
EUR 829

Dystrophia myotonica kinase B15 (Dm15) polyclonal antibody

ABP-PAB-10617 100 ug Ask for price

DM-3

ABC-TC0212 1 vial Ask for price
Description: Established from a pleural biopsy of a 62-year-old man with malignant mesothelioma.

DM1

ADC-P-033 unit Ask for price

DM4

ADC-P-034 unit Ask for price

DM4

HY-12454 100mg
EUR 3531.6

DM3

T11058-10mg 10mg Ask for price
Description: DM3

DM3

T11058-1g 1g Ask for price
Description: DM3

DM3

T11058-1mg 1mg Ask for price
Description: DM3

DM3

T11058-50mg 50mg Ask for price
Description: DM3

DM3

T11058-5mg 5mg Ask for price
Description: DM3

DM4

T15141-10mg 10mg Ask for price
Description: DM4

DM4

T15141-1g 1g Ask for price
Description: DM4

DM4

T15141-1mg 1mg Ask for price
Description: DM4

DM4

T15141-50mg 50mg Ask for price
Description: DM4

DM4

T15141-5mg 5mg Ask for price
Description: DM4

CSB-PA644917LA01BO(2019年开始买这个,换个lot)

43478 100μg
EUR 390

Anti-CSB/ERCC6 Antibody

PB10060 100ug/vial
EUR 352.8

DM4-d6

D198091 25mg
EUR 12800

17-DMAG

20-abx076602
  • Ask for price
  • Ask for price
  • 1 mg
  • 5 mg

DM1-SMe

407263 1.0mg
EUR 90

DM1 ADC EIA Kit

DEIABL311 96T Ask for price
Description: This test kit is intended for use in the quantitative determination of antibody-DM1-conjugate level in test sample. It is useful for preclinical and clinical pharmacology study of DM1 Antibody Drug Conjugate (ADC). - Samples from tissue/cell culture a

D8-MMAE

ADC-P-008 unit Ask for price

DM3-SMe

HY-130081 100mg
EUR 5760

DM4-SMe

HY-130082 45mg
EUR 3504

D8-MMAE

HY-15162A 5mg
EUR 4192.8

D8-MMAF

HY-15579S 10mg
EUR 7828.8

D8-MMAD

HY-15581S 10mM/1mL
EUR 6718.8

17-DMAG

SIH-114-5MG 5 mg
EUR 404
Description: Hsp90 inhibitor

17-DMAG

SIH-114A 1 mg
EUR 123
Description: Hsp90 inhibitor

DM3-SMe

T11057-10mg 10mg Ask for price
Description: DM3-SMe

DM3-SMe

T11057-1g 1g Ask for price
Description: DM3-SMe

DM3-SMe

T11057-1mg 1mg Ask for price
Description: DM3-SMe

DM3-SMe

T11057-50mg 50mg Ask for price
Description: DM3-SMe

DM3-SMe

T11057-5mg 5mg Ask for price
Description: DM3-SMe

DM4-SMe

T11059-10mg 10mg Ask for price
Description: DM4-SMe

DM4-SMe

T11059-1g 1g Ask for price
Description: DM4-SMe

DM4-SMe

T11059-1mg 1mg Ask for price
Description: DM4-SMe

DM4-SMe

T11059-50mg 50mg Ask for price
Description: DM4-SMe

DM4-SMe

T11059-5mg 5mg Ask for price
Description: DM4-SMe

D8-MMAD

T10947-10mg 10mg Ask for price
Description: D8-MMAD

D8-MMAD

T10947-1g 1g Ask for price
Description: D8-MMAD

D8-MMAD

T10947-1mg 1mg Ask for price
Description: D8-MMAD

D8-MMAD

T10947-50mg 50mg Ask for price
Description: D8-MMAD

D8-MMAD

T10947-5mg 5mg Ask for price
Description: D8-MMAD

D8-MMAF

T10949-10mg 10mg Ask for price
Description: D8-MMAF

D8-MMAF

T10949-1g 1g Ask for price
Description: D8-MMAF

D8-MMAF

T10949-1mg 1mg Ask for price
Description: D8-MMAF

D8-MMAF

T10949-50mg 50mg Ask for price
Description: D8-MMAF

D8-MMAF

T10949-5mg 5mg Ask for price
Description: D8-MMAF

DM1-MCC

T24007-10mg 10mg Ask for price
Description: DM1-MCC

DM1-MCC

T24007-1g 1g Ask for price
Description: DM1-MCC

DM1-MCC

T24007-1mg 1mg Ask for price
Description: DM1-MCC

DM1-MCC

T24007-50mg 50mg Ask for price
Description: DM1-MCC

DM1-MCC

T24007-5mg 5mg Ask for price
Description: DM1-MCC

DM1-SMe

T21408-10mg 10mg Ask for price
Description: DM1-SMe

DM1-SMe

T21408-1g 1g Ask for price
Description: DM1-SMe

DM1-SMe

T21408-1mg 1mg Ask for price
Description: DM1-SMe

DM1-SMe

T21408-50mg 50mg Ask for price
Description: DM1-SMe

DM1-SMe

T21408-5mg 5mg Ask for price
Description: DM1-SMe

DM1-SMCC

407202 2.0mg
EUR 150

DM4-SPDP

HY-126493 50mg
EUR 12726

DM4-SMCC

HY-126494 50mg
EUR 11143.2

DM4-SMCC

T17833-10mg 10mg Ask for price
Description: DM4-SMCC

DM4-SMCC

T17833-1g 1g Ask for price
Description: DM4-SMCC

DM4-SMCC

T17833-1mg 1mg Ask for price
Description: DM4-SMCC

DM4-SMCC

T17833-50mg 50mg Ask for price
Description: DM4-SMCC

DM4-SMCC

T17833-5mg 5mg Ask for price
Description: DM4-SMCC

DM4-SPDP

T17834-10mg 10mg Ask for price
Description: DM4-SPDP

DM4-SPDP

T17834-1g 1g Ask for price
Description: DM4-SPDP

DM4-SPDP

T17834-1mg 1mg Ask for price
Description: DM4-SPDP

DM4-SPDP

T17834-50mg 50mg Ask for price
Description: DM4-SPDP

DM4-SPDP

T17834-5mg 5mg Ask for price
Description: DM4-SPDP

DM4 hydrate

464823 5.0mg
EUR 260

17-DMAP-GA

ADC-P-084 unit Ask for price

S-methyl DM1

T12805-10mg 10mg Ask for price
Description: S-methyl DM1

S-methyl DM1

T12805-1g 1g Ask for price
Description: S-methyl DM1

S-methyl DM1

T12805-1mg 1mg Ask for price
Description: S-methyl DM1

S-methyl DM1

T12805-50mg 50mg Ask for price
Description: S-methyl DM1

S-methyl DM1

T12805-5mg 5mg Ask for price
Description: S-methyl DM1

2,4-D-methyl

T20394-10mg 10mg Ask for price
Description: 2,4-D-methyl

2,4-D-methyl

T20394-1g 1g Ask for price
Description: 2,4-D-methyl

2,4-D-methyl

T20394-1mg 1mg Ask for price
Description: 2,4-D-methyl

2,4-D-methyl

T20394-50mg 50mg Ask for price
Description: 2,4-D-methyl

2,4-D-methyl

T20394-5mg 5mg Ask for price
Description: 2,4-D-methyl

17-DMAP-GA

T39158-10mg 10mg Ask for price
Description: 17-DMAP-GA

17-DMAP-GA

T39158-1g 1g Ask for price
Description: 17-DMAP-GA

17-DMAP-GA

T39158-1mg 1mg Ask for price
Description: 17-DMAP-GA

17-DMAP-GA

T39158-50mg 50mg Ask for price
Description: 17-DMAP-GA

17-DMAP-GA

T39158-5mg 5mg Ask for price
Description: 17-DMAP-GA

His-[D-2-ME-Trp]-Ala

HY-P1460 10mM/1mL
EUR 590.4

Fmoc-3,3-dmP-OH (S)

F209340 2.5g
EUR 7600
Description: 1982344-79-5

His-[D-2-ME-Trp]-Ala

TP1426-10mg 10mg Ask for price
Description: His-[D-2-ME-Trp]-Ala

His-[D-2-ME-Trp]-Ala

TP1426-1g 1g Ask for price
Description: His-[D-2-ME-Trp]-Ala

His-[D-2-ME-Trp]-Ala

TP1426-1mg 1mg Ask for price
Description: His-[D-2-ME-Trp]-Ala

His-[D-2-ME-Trp]-Ala

TP1426-50mg 50mg Ask for price
Description: His-[D-2-ME-Trp]-Ala

His-[D-2-ME-Trp]-Ala

TP1426-5mg 5mg Ask for price
Description: His-[D-2-ME-Trp]-Ala

4-Nitrophenyl 3,6-di-O-(α-D-mannopyranosyl)-α-D-mannopyranoside

GC6978-10 10
EUR 820.3

4-Nitrophenyl 3,6-di-O-(α-D-mannopyranosyl)-α-D-mannopyranoside

GC6978-2 2
EUR 298.3

4-Nitrophenyl 3,6-di-O-(α-D-mannopyranosyl)-α-D-mannopyranoside

GC6978-25 25
EUR 1659.2

4-Nitrophenyl 3,6-di-O-(α-D-mannopyranosyl)-α-D-mannopyranoside

GC6978-5 5
EUR 550.1

2-Azidoethyl 3,6-di-O-(α-D-mannopyranosyl)-α-D-mannopyranoside

GC2770-1 1
EUR 289

2-Azidoethyl 3,6-di-O-(α-D-mannopyranosyl)-α-D-mannopyranoside

GC2770-10 10
EUR 1454.2

2-Azidoethyl 3,6-di-O-(α-D-mannopyranosyl)-α-D-mannopyranoside

GC2770-2 2
EUR 428.8

2-Azidoethyl 3,6-di-O-(α-D-mannopyranosyl)-α-D-mannopyranoside

GC2770-5 5
EUR 838.9

4-Aminophenyl 3,6-di-O-(α-D-mannopyranosyl)-α-D-mannopyranoside

GC1550-1 1
EUR 279.6

4-Aminophenyl 3,6-di-O-(α-D-mannopyranosyl)-α-D-mannopyranoside

GC1550-10 10
EUR 1099.9

4-Aminophenyl 3,6-di-O-(α-D-mannopyranosyl)-α-D-mannopyranoside

GC1550-2 2
EUR 400.9

4-Aminophenyl 3,6-di-O-(α-D-mannopyranosyl)-α-D-mannopyranoside

GC1550-25 25
EUR 2125.3

As a main predictor, depressive symptoms were measured by the five-item version of the Geriatrics Depression Scale (GDS-5). As possible confounders, we considered cognitive function, body mass index, solitary living, education, economic status, medical history of stroke and heart disease, hypertension, dyslipidemia, diabetes, and sex. We obtained odds ratios (ORs) of IADL decline for having depressive symptoms in each age group (70s/80s) and tested interactions between depressive symptoms and age groups in relation to IADL decline in 3 years by logistic regression. Additionally, to confirm age group differences, we conducted multiple group analysis.There were 559 participants in their 70s and 519 in their 80s. Compared to participants without depressive symptoms, those with depressive symptoms had higher OR of IADL decline in 70s (OR [95% CI] = 2.33 [1.13, 4.78]), but not in 80s (OR [95% CI] = 0.85 [0.46, 1.53]). There were significant interactions between depressive symptoms and age groups in relation to IADL decline (p-value = 0.03). Multiple group analyses showed differences between the age groups by Akaike information criterion (AIC), and ORs (95%CI) decline for depressive symptoms was 2.33 (1.14, 4.77) in 70s and 0.85 (0.47, 1.54) in 80s.The association of depressive symptoms and IADL decline during the 3 years was significantly different between the 70s and 80s age groups, and significant association was found only in people in their 70s. Detecting depressive symptoms may be a key for preventing IADL decline in people in their 70s and not for those in their 80s.