Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors.

Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors.

Cells from organisms with renewable tissues can completely withdraw from the cell cycle in response to various stress, together with dysfunctional telomeres, DNA harm, sturdy mitogenic alerts, and disrupted chromatin. This response, termed mobile senescence, is managed by the p53 and RB tumor suppressor proteins and constitutes a potent anticancer mechanism.

Nonetheless, senescent cells purchase phenotypic modifications which will contribute to ageing and sure age-related ailments, together with late-life most cancers. Thus, the senescence response could also be antagonistically pleiotropic, selling early-life survival by curbing the event of most cancers however ultimately limiting longevity as dysfunctional senescent cells accumulate.

Numerous research reveal hyperlinks between persistent stress and indices of poor well being, together with danger components for heart problems and poorer immune operate. Nevertheless, the precise mechanisms of how stress will get “underneath the pores and skin” stay elusive. We investigated the speculation that stress impacts well being by modulating the speed of mobile ageing.

Here we offer proof that psychological stress–both perceived stress and chronicity of stress–is considerably related to larger oxidative stress, decrease telomerase exercise, and shorter telomere size, that are recognized determinants of cell senescence and longevity, in peripheral blood mononuclear cells from wholesome premenopausal girls. Women with the very best ranges of perceived stress have telomeres shorter on common by the equal of no less than one decade of further ageing in comparison with low stress girls. These findings have implications for understanding how, on the mobile degree, stress might promote earlier onset of age-related ailments.

The Caenorhabditis elegans transcription issue HSF-1, which regulates the heat-shock response, additionally influences ageing. Reducing hsf-1 exercise accelerates tissue ageing and shortens life-span, and we present that hsf-1 overexpression extends lifespan. We discover that HSF-1, just like the transcription issue DAF-16, is required for daf-2-insulin/IGF-1 receptor mutations to increase life-span.

Our findings counsel it is because HSF-1 and DAF-16 collectively activate expression of particular genes, together with genes encoding small heat-shock proteins, which in flip promote longevity. The small heat-shock proteins additionally delay the onset of polyglutamine-expansion protein aggregation, suggesting that these proteins couple the conventional ageing course of to such a age-related illness.

The SIR2/3/four advanced and SIR2 alone promote longevity in Saccharomyces cerevisiae by two completely different mechanisms.

 

The SIR genes are determinants of life span in yeast mom cells. Here we present that life span regulation by the Sir proteins is unbiased of their position in nonhomologous finish becoming a member of. The quick life span of a sir3 or sir4 mutant is as a result of simultaneous expression of a and alpha mating-type data, which not directly causes a rise in rDNA recombination and possible will increase the manufacturing of extrachromosomal rDNA circles.
The quick life span of a sir2 mutant additionally reveals a direct failure to repress recombination generated by the Fob1p-mediated replication block within the rDNA. Sir2p is a limiting element in selling yeast longevity, and rising the gene dosage extends the life span in wild-type cells. A attainable position of the conserved SIR2 in mammalian ageing is mentioned.
Calorie restriction extends life-span in all kinds of organisms. Although it has been steered that calorie restriction may match by lowering the degrees of reactive oxygen species produced throughout respiration, the mechanism by which this routine slows ageing is unsure. Here, we mimicked calorie restriction in yeast by physiological or genetic means and confirmed a considerable extension in life-span. This extension was not noticed in strains mutant for SIR2 (which encodes the silencing protein Sir2p) or NPT1 (a gene in a pathway within the synthesis of NAD, the oxidized type of nicotinamide adenine dinucleotide). These findings counsel that the elevated longevity induced by calorie restriction requires the activation of Sir2p by NAD.
The Drosophila melanogaster gene chico encodes an insulin receptor substrate that features in an insulin/insulin-like development issue (IGF) signaling pathway. In the nematode Caenorhabditis elegans, insulin/IGF signaling regulates grownup longevity. We discovered that mutation of chico extends fruit fly median life-span by as much as 48% in homozygotes and 36% in heterozygotes. Extension of life-span was not a results of impaired oogenesis in chico females, nor was it persistently correlated with elevated stress resistance. The dwarf phenotype of chico homozygotes was additionally pointless for extension of life-span. The position of insulin/IGF signaling in regulating animal ageing is due to this fact evolutionarily conserved.
Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors.

Autophagy and ageing.

 

To decide the position of reactive oxygen species in mammalian longevity, we generated transgenic mice that overexpress human catalase localized to the peroxisome, the nucleus, or mitochondria (MCAT). Median and most life spans had been maximally elevated (averages of 5 months and 5.5 months, respectively) in MCAT animals. Cardiac pathology and cataract improvement had been delayed, oxidative harm was diminished, H2O2 manufacturing and H2O2-induced aconitase inactivation had been attenuated, and the event of mitochondrial deletions was diminished. These outcomes help the free radical concept of ageing and reinforce the significance of mitochondria as a supply of those radicals.

Genetic inhibition of autophagy induces degenerative modifications in mammalian tissues that resemble these related to ageing, and regular and pathological ageing are sometimes related to a diminished autophagic potential. Pharmacological or genetic manipulations that improve life span in mannequin organisms typically stimulate autophagy, and its inhibition compromises the longevity-promoting results of caloric restriction, Sirtuin 1 activation, inhibition of insulin/insulin development issue signaling, or the administration of rapamycin, resveratrol, or spermidine.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
DLR-LASS2-Hu-48T 48T
EUR 664.8
Description: A sandwich quantitative ELISA assay kit for detection of Human Longevity Assurance Homolog 2 (LASS2) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
DLR-LASS2-Hu-96T 96T
EUR 870
Description: A sandwich quantitative ELISA assay kit for detection of Human Longevity Assurance Homolog 2 (LASS2) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKU05672-48T 48T
EUR 610.82

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKU05672-5x96T 5x96T
EUR 4144.85

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKU05672-96T 96T
EUR 872.6

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKN46783-48T 48T
EUR 416.29

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKN46783-5x96T 5x96T
EUR 2824.83

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EKN46783-96T 96T
EUR 594.7

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
DL-LASS2-Hu 96T
EUR 481
Description: tissue homogenates, cell lysates or other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
EK15188 96Т
EUR 768

Human Longevity Assurance Homolog 2 (CERS2) ELISA Kit
abx388232-96tests 96 tests
EUR 1093.2

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
20-abx152171
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RD-LASS2-Hu-48T 48T
EUR 493.5
Description: tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RD-LASS2-Hu-48Tests 48 Tests
EUR 675.6

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RD-LASS2-Hu-96T 96T
EUR 705
Description: tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RD-LASS2-Hu-96Tests 96 Tests
EUR 939.6

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
SEP312Hu-10x96wellstestplate 10x96-wells test plate
EUR 6227.58
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
SEP312Hu-1x48wellstestplate 1x48-wells test plate
EUR 618.04
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
SEP312Hu-1x96wellstestplate 1x96-wells test plate
EUR 831.48
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
SEP312Hu-5x96wellstestplate 5x96-wells test plate
EUR 3381.66
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 2 (LASS2) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
4-SEP312Hu
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  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Longevity Assurance Homolog 2 (LASS2) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RDR-LASS2-Hu-48T 48T
EUR 518.18
Description: tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RDR-LASS2-Hu-48Tests 48 Tests
EUR 706.8

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RDR-LASS2-Hu-96T 96T
EUR 740.25
Description: tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 2 (LASS2) ELISA Kit
RDR-LASS2-Hu-96Tests 96 Tests
EUR 984

Human LASS6(Longevity Assurance Homolog 6) ELISA Kit
ELK7613-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human LASS6. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human LASS6. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human LASS6, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human LASS6 in the samples is then determined by comparing the OD of the samples to the standard curve.

Human LASS6(Longevity Assurance Homolog 6) ELISA Kit
ELK7613-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human LASS6. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human LASS6. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human LASS6, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human LASS6 in the samples is then determined by comparing the OD of the samples to the standard curve.

ELISA kit for Human LASS2 (Longevity Assurance Homolog 2)
ELK7214 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Longevity Assurance Homolog 2 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Human LAG1 longevity assurance homolog 2 (LASS2) ELISA Kit
EK10151 96Т
EUR 799

Human LAG1 longevity assurance homolog 2 (LASS2) ELISA Kit
AE35962HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 2 (LASS2) ELISA Kit
AE35962HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
EKU09363-48T 48T
EUR 610.82

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
EKU09363-5x96T 5x96T
EUR 4144.85

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
EKU09363-96T 96T
EUR 872.6

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
EKN50474-48T 48T
EUR 380.31

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
EKN50474-5x96T 5x96T
EUR 2580.68

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
EKN50474-96T 96T
EUR 543.3

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
20-abx258682
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
SER156Hu-10x96wellstestplate 10x96-wells test plate
EUR 6227.58
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 6 (LASS6) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
SER156Hu-1x48wellstestplate 1x48-wells test plate
EUR 618.04
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 6 (LASS6) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
SER156Hu-1x96wellstestplate 1x96-wells test plate
EUR 831.48
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 6 (LASS6) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
SER156Hu-5x96wellstestplate 5x96-wells test plate
EUR 3381.66
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Longevity Assurance Homolog 6 (LASS6) in Tissue homogenates, cell lysates and other biological fluids.

Human Longevity Assurance Homolog 6 (LASS6) ELISA Kit
4-SER156Hu
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  • Ask for price
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Longevity Assurance Homolog 6 (LASS6) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E02A0057-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E02A0057-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E02A0057-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E07A0057-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E07A0057-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E07A0057-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E08A0057-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E08A0057-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E08A0057-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

ELISA kit for Human LAG1 longevity assurance homolog 2 (LASS2)
KTE61853-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 2 (LASS2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human LAG1 longevity assurance homolog 2 (LASS2)
KTE61853-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 2 (LASS2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human LAG1 longevity assurance homolog 2 (LASS2)
KTE61853-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 2 (LASS2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Longevity Assurance Homolog 2 (LASS2) Antibody
20-abx173382
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  • 1 mg
  • 200 ug

Longevity Assurance Homolog 2 (LASS2) Antibody
20-abx177383
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  • 1 mg
  • 200 ug

Longevity Assurance Homolog 2 (LASS2) Antibody
abx234705-100ug 100 ug
EUR 661.2

Goat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E06A0057-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E06A0057-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E06A0057-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

ELISA kit for Human LASS6 (Longevity Assurance Homolog 6)
ELK7613 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Longevity Assurance Homolog 6 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E01A0057-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E01A0057-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E03A0057-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E03A0057-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E03A0057-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human LAG1 longevity assurance homolog 6 (LASS6) ELISA Kit
EK10150 96Т
EUR 799

Human LAG1 longevity assurance homolog 6 (LASS6) ELISA Kit
AE35956HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 6 (LASS6) ELISA Kit
AE35956HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 4 (LASS4) ELISA Kit
AE35958HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 4 (LASS4) ELISA Kit
AE35958HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 1 (LASS1) ELISA Kit
AE35965HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human LAG1 longevity assurance homolog 1 (LASS1) ELISA Kit
AE35965HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

Mouse LAG1 longevity assurance homolog 1 (LASS1) ELISA Kit
RK12828 96T
EUR 280

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA Kit
NSL1442Hu 96 wells
EUR 468

Human LAG1 longevity assurance homolog 1 (LASS1) ELISA Kit
RK10479 96T
EUR 280

Human Longevity Assurance Homolog 2 (LASS2) CLIA Kit
20-abx496121
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rabbit LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E04A0057-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E04A0057-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E04A0057-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E09A0057-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E09A0057-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E09A0057-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Bovine LAG1 longevity assurance homolog 3(LASS3) ELISA Kit
NSL1118Bo 96 T
EUR 528

Canine LAG1 longevity assurance homolog 3(LASS3) ELISA Kit
NSL1145Ca 1240 wells
EUR 528

Rat LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A8819 96T
EUR 700
Description: ELISA

Goat LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A43740 96T
EUR 700
Description: ELISA

Human LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A0054 96T
EUR 700
Description: ELISA

Sheep LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A96033 96T
EUR 700
Description: ELISA

Mouse LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A17561 96T
EUR 700
Description: ELISA

Canine LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A61175 96T
EUR 700
Description: ELISA

Rabbit LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A26308 96T
EUR 700
Description: ELISA

Bovine LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A78604 96T
EUR 700
Description: ELISA

Monkey LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A69887 96T
EUR 700
Description: ELISA

ELISA kit for Human LAG1 longevity assurance homolog 6 (LASS6)
KTE61852-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 6 (LASS6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human LAG1 longevity assurance homolog 6 (LASS6)
KTE61852-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 6 (LASS6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human LAG1 longevity assurance homolog 6 (LASS6)
KTE61852-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Human LAG1 longevity assurance homolog 6 (LASS6) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Porcine LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A52457 96T
EUR 700
Description: ELISA

Chicken LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A87330 96T
EUR 700
Description: ELISA

Guinea pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E05A0057-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E05A0057-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig LAG1 longevity assurance homolog 3 (LASS3) ELISA kit
E05A0057-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig LAG1 longevity assurance homolog 3 (LASS3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Longevity Assurance Homolog 2 (LASS2) Protein
20-abx654210
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

LAG1 Longevity Assurance Homolog 2 (LASS2) Antibody
abx019124-100ug 100 ug
EUR 410.4

Longevity Assurance Homolog 6 (LASS6) Antibody
abx029719-400ul 400 ul
EUR 627.6

Longevity Assurance Homolog 6 (LASS6) Antibody
abx029719-80l 80 µl
EUR 343.2

Human Longevity Assurance Homolog 6 (LASS6) CLIA Kit
20-abx496220
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Guinea Pig LAG1 longevity assurance homolog 3 (LASS3) ELISA
E01A35022 96T
EUR 700
Description: ELISA

Longevity Assurance Homolog 2 (LASS2) Magnetic Luminex Assay Kit
LKU602152-96T 96T
EUR 1062.6

LAG1 Longevity Assurance Homolog 3 (LASS3) Antibody
abx430427-200ul 200 ul
EUR 460.8

LAG1 Longevity Assurance Homolog 4 (LASS4) Antibody
20-abx008040
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  • 100 ul
  • 200 ul
  • 30 ul

LAG1 Longevity Assurance Homolog 4 (LASS4) Antibody
20-abx013801
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  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

LAG1 Longevity Assurance Homolog 4 (LASS4) Antibody
abx013801-100l 100 µl
EUR 43.75

Longevity Assurance Homolog 6 (LASS6) Magnetic Luminex Assay Kit
LKU602157-96T 96T
EUR 1062.6

Longevity Assurance Gene 1 Protein Homolog 1 (LASS1) Antibody
abx432242-200ul 200 ul
EUR 460.8

Longevity Assurance Gene 1 Protein Homolog 1 (LASS1) Antibody
abx432242-100g 100 µg
EUR 387.5

Cers2 (GFP-tagged) - Mouse longevity assurance homolog 2 (S. cerevisiae) (Lass2)
MG205931 10 µg Ask for price

Cers6 (GFP-tagged) - Mouse longevity assurance homolog 6 (S. cerevisiae) (Lass6)
MG205998 10 µg Ask for price

Cers4 (GFP-tagged) - Mouse longevity assurance homolog 4 (S. cerevisiae) (Lass4)
MG206130 10 µg Ask for price

Cers5 (GFP-tagged) - Mouse longevity assurance homolog 5 (S. cerevisiae) (Lass5)
MG206528 10 µg Ask for price

LASS2 (untagged)-Human LAG1 longevity assurance homolog 2 (S. cerevisiae) (LASS2), transcript variant 3
SC110410 10 µg Ask for price

Lass5 (GFP-tagged) - Mouse longevity assurance homolog 5 (S. cerevisiae) (cDNA clone MGC:57962 IMAGE:6419704)
MG206047 10 µg Ask for price

Lass5 (Myc-DDK-tagged) - Mouse longevity assurance homolog 5 (S. cerevisiae) (cDNA clone MGC:57962 IMAGE:6419704)
MR206047 10 µg Ask for price

LASS3 (untagged)-Human LAG1 longevity assurance homolog 3 (S. cerevisiae) (cDNA clone MGC:26920 IMAGE:4837657), complete cds
SC122492 10 µg Ask for price

Lenti ORF clone of Lass5 (mGFP-tagged) - Mouse longevity assurance homolog 5 (S. cerevisiae) (cDNA clone MGC:57962 IMAGE:6419704)
MR206047L4 10 µg Ask for price

Lenti ORF clone of Lass5 (Myc-DDK-tagged) - Mouse longevity assurance homolog 5 (S. cerevisiae) (cDNA clone MGC:57962 IMAGE:6419704)
MR206047L3 10 µg Ask for price

Lenti ORF particles, Lass5 (GFP-tagged) - Mouse longevity assurance homolog 5 (S. cerevisiae) (cDNA clone MGC:57962 IMAGE:6419704), 200ul, >10^7
MR206047L4V 200 µl Ask for price

Lenti ORF particles, Lass5 (Myc-DDK-tagged) - Mouse longevity assurance homolog 5 (S. cerevisiae) (cDNA clone MGC:57962 IMAGE:6419704), 200ul, >1
MR206047L3V 200 µl Ask for price

Assurance Grade Water Blank for ICP 2 L - 2L
PLBLK-H2O-2L 2L
EUR 147.15

Assurance Grade Water Blank for ICP 500mL
PLBLK-HCL 500ML
EUR 58.29

Assurance Grade Water Blank for ICP 1 L - 1L
PLBLK-H2O-1L 1L
EUR 117.45

Assurance Grade Water Blank for ICP 4 L - 4L
PLBLK-H2O-4L 4L
EUR 170.1

Assurance Grade Water Blank for ICP 500mL - 500ML
PLBLK-H2O 500ML
EUR 98.55

Here, we talk about the possible trigger and impact relationship between perturbed autophagy and ageing, in addition to attainable molecular mechanisms which will mediate the anti-ageing results of autophagy.

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